Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
CONCLUSION: This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated SARS-CoV-2 vaccination and serves as the basis for future research to improve the immunogenicity of inactivated vaccines.PMID:38085470 | DOI:10.1007/s12519-023-00764-0 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 12, 2023 Category: Pediatrics Authors: Jaime S Rosa Duque Samuel M S Cheng Carolyn A Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H W Wong Leo C H Tsang Sara Chaothai Tsz Chun Kwan John K C Li Karl C K Chan Leo L H Luk Jenson C Source Type: research
Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
CONCLUSION: This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated SARS-CoV-2 vaccination and serves as the basis for future research to improve the immunogenicity of inactivated vaccines.PMID:38085470 | DOI:10.1007/s12519-023-00764-0 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 12, 2023 Category: Pediatrics Authors: Jaime S Rosa Duque Samuel M S Cheng Carolyn A Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H W Wong Leo C H Tsang Sara Chaothai Tsz Chun Kwan John K C Li Karl C K Chan Leo L H Luk Jenson C Source Type: research
Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
CONCLUSION: This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated SARS-CoV-2 vaccination and serves as the basis for future research to improve the immunogenicity of inactivated vaccines.PMID:38085470 | DOI:10.1007/s12519-023-00764-0 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 12, 2023 Category: Pediatrics Authors: Jaime S Rosa Duque Samuel M S Cheng Carolyn A Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H W Wong Leo C H Tsang Sara Chaothai Tsz Chun Kwan John K C Li Karl C K Chan Leo L H Luk Jenson C Source Type: research
Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
CONCLUSION: This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated SARS-CoV-2 vaccination and serves as the basis for future research to improve the immunogenicity of inactivated vaccines.PMID:38085470 | DOI:10.1007/s12519-023-00764-0 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 12, 2023 Category: Pediatrics Authors: Jaime S Rosa Duque Samuel M S Cheng Carolyn A Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H W Wong Leo C H Tsang Sara Chaothai Tsz Chun Kwan John K C Li Karl C K Chan Leo L H Luk Jenson C Source Type: research
Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
CONCLUSION: This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated SARS-CoV-2 vaccination and serves as the basis for future research to improve the immunogenicity of inactivated vaccines.PMID:38085470 | DOI:10.1007/s12519-023-00764-0 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 12, 2023 Category: Pediatrics Authors: Jaime S Rosa Duque Samuel M S Cheng Carolyn A Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H W Wong Leo C H Tsang Sara Chaothai Tsz Chun Kwan John K C Li Karl C K Chan Leo L H Luk Jenson C Source Type: research
Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
CONCLUSION: This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated SARS-CoV-2 vaccination and serves as the basis for future research to improve the immunogenicity of inactivated vaccines.PMID:38085470 | DOI:10.1007/s12519-023-00764-0 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 12, 2023 Category: Pediatrics Authors: Jaime S Rosa Duque Samuel M S Cheng Carolyn A Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H W Wong Leo C H Tsang Sara Chaothai Tsz Chun Kwan John K C Li Karl C K Chan Leo L H Luk Jenson C Source Type: research
Perioperative complication incidence and risk factors for retroperitoneal neuroblastoma in children: analysis of 571 patients
CONCLUSIONS: Despite the high incidence of perioperative complications, the associated mortality rate was quite low. Perioperative complications of retroperitoneal neuroblastoma were associated with IDRFs, INRGSS, retroperitoneal lymph node metastasis and vascular encasement. Patients with high-risk factors should receive more serious attention during surgery but should not discourage the determination to pursue total resection of neuroblastoma. Video Abstract (MP4 94289 KB).PMID:38070095 | DOI:10.1007/s12519-023-00773-z (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Min He Jia-Bin Cai Xuan Wu Yin-Bing Tang Jin-Yan Wang Jun-Qin Mao Ji-Jun Chen Li-Feng Zhang Zhong-Hai Guan Jie-Ni Xiong Wan-Xin Peng Jin-Hu Wang Ting Tao Source Type: research
Variable phenotypes and outcomes associated with the MMACHC c.482G & gt; A mutation: follow-up in a large CblC disease cohort
CONCLUSIONS: The c.482G > A variant in MMACHC is associated with late-onset and milder phenotypes of CblC disease. Patients with this mutation tend to have a relatively better response to hydroxocobalamin, better metabolic control, and more favorable neurological outcomes. NBS and other appropriate pre-symptomatic treatments seem to be helpful in early diagnosis, resulting in favorable clinical outcomes. Video Abstract (MP4 136794 kb).PMID:38070096 | DOI:10.1007/s12519-023-00770-2 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Sheng-Nan Wu Hui-Shu E Yue Yu Shi-Ying Ling Li-Li Liang Wen-Juan Qiu Hui-Wen Zhang Rui-Xue Shuai Hai-Yan Wei Chi-Ju Yang Peng Xu Xi-Gui Chen Hui Zou Ji-Zhen Feng Ting-Ting Niu Hai-Li Hu Kai-Chuang Zhang De-Yun Lu Zhu-Wen Gong Xia Zhan Wen-Jun Ji Xue-Fan G Source Type: research
Epidemiology of congenital diaphragmatic hernia among 24 million Chinese births: a hospital-based surveillance study
CONCLUSION: The increasing prevalence and high perinatal mortality rate of CDH highlight the need for further etiological, epidemiological, and clinical studies among the Chinese population. Video Abstract.PMID:38070097 | DOI:10.1007/s12519-023-00774-y (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Zhi-Yu Chen Jing Tao Wen-Li Xu Yu-Yang Gao Wen-Yan Li Zhen Liu Jia-Yuan Zhou Li Dai Source Type: research
Adrenocorticotropic hormone combined with magnesium sulfate therapy for infantile epileptic spasms syndrome: a real-world study
CONCLUSION: Our findings support that ACTH combined with MgSO4 is a more effective short-term treatment protocol for patients with IESS than ACTH alone, especially for those patients with short lead times to treatment. Video Abstract (MP4 533623 KB).PMID:38070098 | DOI:10.1007/s12519-023-00771-1 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Wen He Qiu-Hong Wang Jiu-Wei Li Yang-Yang Wang Xiao-Mei Luo Lin Wan Jing Wang Xiu-Yu Shi Wei-Hua Zhang Fang Fang Li-Ping Zou Source Type: research
Perioperative complication incidence and risk factors for retroperitoneal neuroblastoma in children: analysis of 571 patients
CONCLUSIONS: Despite the high incidence of perioperative complications, the associated mortality rate was quite low. Perioperative complications of retroperitoneal neuroblastoma were associated with IDRFs, INRGSS, retroperitoneal lymph node metastasis and vascular encasement. Patients with high-risk factors should receive more serious attention during surgery but should not discourage the determination to pursue total resection of neuroblastoma. Video Abstract (MP4 94289 KB).PMID:38070095 | DOI:10.1007/s12519-023-00773-z (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Min He Jia-Bin Cai Xuan Wu Yin-Bing Tang Jin-Yan Wang Jun-Qin Mao Ji-Jun Chen Li-Feng Zhang Zhong-Hai Guan Jie-Ni Xiong Wan-Xin Peng Jin-Hu Wang Ting Tao Source Type: research
Variable phenotypes and outcomes associated with the MMACHC c.482G & gt; A mutation: follow-up in a large CblC disease cohort
CONCLUSIONS: The c.482G > A variant in MMACHC is associated with late-onset and milder phenotypes of CblC disease. Patients with this mutation tend to have a relatively better response to hydroxocobalamin, better metabolic control, and more favorable neurological outcomes. NBS and other appropriate pre-symptomatic treatments seem to be helpful in early diagnosis, resulting in favorable clinical outcomes. Video Abstract (MP4 136794 kb).PMID:38070096 | DOI:10.1007/s12519-023-00770-2 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Sheng-Nan Wu Hui-Shu E Yue Yu Shi-Ying Ling Li-Li Liang Wen-Juan Qiu Hui-Wen Zhang Rui-Xue Shuai Hai-Yan Wei Chi-Ju Yang Peng Xu Xi-Gui Chen Hui Zou Ji-Zhen Feng Ting-Ting Niu Hai-Li Hu Kai-Chuang Zhang De-Yun Lu Zhu-Wen Gong Xia Zhan Wen-Jun Ji Xue-Fan G Source Type: research
Epidemiology of congenital diaphragmatic hernia among 24 million Chinese births: a hospital-based surveillance study
CONCLUSION: The increasing prevalence and high perinatal mortality rate of CDH highlight the need for further etiological, epidemiological, and clinical studies among the Chinese population. Video Abstract.PMID:38070097 | DOI:10.1007/s12519-023-00774-y (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Zhi-Yu Chen Jing Tao Wen-Li Xu Yu-Yang Gao Wen-Yan Li Zhen Liu Jia-Yuan Zhou Li Dai Source Type: research
Adrenocorticotropic hormone combined with magnesium sulfate therapy for infantile epileptic spasms syndrome: a real-world study
CONCLUSION: Our findings support that ACTH combined with MgSO4 is a more effective short-term treatment protocol for patients with IESS than ACTH alone, especially for those patients with short lead times to treatment. Video Abstract (MP4 533623 KB).PMID:38070098 | DOI:10.1007/s12519-023-00771-1 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Wen He Qiu-Hong Wang Jiu-Wei Li Yang-Yang Wang Xiao-Mei Luo Lin Wan Jing Wang Xiu-Yu Shi Wei-Hua Zhang Fang Fang Li-Ping Zou Source Type: research
Perioperative complication incidence and risk factors for retroperitoneal neuroblastoma in children: analysis of 571 patients
CONCLUSIONS: Despite the high incidence of perioperative complications, the associated mortality rate was quite low. Perioperative complications of retroperitoneal neuroblastoma were associated with IDRFs, INRGSS, retroperitoneal lymph node metastasis and vascular encasement. Patients with high-risk factors should receive more serious attention during surgery but should not discourage the determination to pursue total resection of neuroblastoma. Video Abstract (MP4 94289 KB).PMID:38070095 | DOI:10.1007/s12519-023-00773-z (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - December 9, 2023 Category: Pediatrics Authors: Min He Jia-Bin Cai Xuan Wu Yin-Bing Tang Jin-Yan Wang Jun-Qin Mao Ji-Jun Chen Li-Feng Zhang Zhong-Hai Guan Jie-Ni Xiong Wan-Xin Peng Jin-Hu Wang Ting Tao Source Type: research
