Reference values of serum total IgE in Uppsala - comparison over four decades
CONCLUSION: The calculated ULN values were similar between the cohorts. We conclude that the total IgE reference values shown for Uppsala subjects from 1974 are still valid and suitable also for the ImmunoCAP Total IgE assay. The 100 kU/L threshold for total IgE had a low sensitivity but high specificity for atopy, asthma, and allergy.PMID:38084204 | PMC:PMC10710850 | DOI:10.48101/ujms.v128.9892 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Robert Mov érare Eilif Persson Andrei Malinovschi Christer Janson Source Type: research

Recreational use of nitrous oxide causes seizure, pneumothorax, pneumomediastinum, and pneumopericardium: nitrous oxide and its harm, a case report
Ups J Med Sci. 2023 Dec 8;128. doi: 10.48101/ujms.v128.10281. eCollection 2023.ABSTRACTNitrous oxide, commonly known as 'laughing gas', has become a popular recreational drug. Whippets, small canisters containing gas in pressurized form, can be easily obtained from a food store. However, inhaling nitrous oxide from these canisters, which contain a 100% concentration, can lead to hypoxia, resulting in seizures or even death. Inhalation of nitrous oxide rarely causes pneumothorax, pneumomediastinum, and pneumopericardium. This case study highlights the potential dangers of recreational abuse of nitrous oxide.PMID:38084205 | ...
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Lee Ti Davidson Source Type: research

Vitamin D status in longstanding type 1 diabetes and controls. Association with upper extremity impairments
CONCLUSION: In patients with type 1 diabetes and a duration of 20 years or more, vitamin D level is not lower than in nondiabetic controls and is not associated with UEIs.PMID:38084202 | PMC:PMC10710851 | DOI:10.48101/ujms.v128.9888 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Hans J Arnqvist Per Leanderson Anna Sp ångeus Source Type: research

A light at the end of the tunnel - from mutation identification to a potential treatment for Alzheimer's disease
Ups J Med Sci. 2023 Nov 28;128. doi: 10.48101/ujms.v128.10316. eCollection 2023.ABSTRACTRecent advances have driven the development of immunotherapies that act by either promoting or suppressing a patient's immune system to treat inflammation, autoimmune disease, cardiovascular disease, infectious diseases, and several cancers. In addition, research conducted over the past 25 years has identified therapeutic targets and indicated that immunotherapy could be used to treat Alzheimer's disease (AD). Despite a number of setbacks, this approach has now led to the development of the first disease-modifying treatments for this de...
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Lars Lannfelt Source Type: research

Reference values of serum total IgE in Uppsala - comparison over four decades
CONCLUSION: The calculated ULN values were similar between the cohorts. We conclude that the total IgE reference values shown for Uppsala subjects from 1974 are still valid and suitable also for the ImmunoCAP Total IgE assay. The 100 kU/L threshold for total IgE had a low sensitivity but high specificity for atopy, asthma, and allergy.PMID:38084204 | PMC:PMC10710850 | DOI:10.48101/ujms.v128.9892 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Robert Mov érare Eilif Persson Andrei Malinovschi Christer Janson Source Type: research

Recreational use of nitrous oxide causes seizure, pneumothorax, pneumomediastinum, and pneumopericardium: nitrous oxide and its harm, a case report
Ups J Med Sci. 2023 Dec 8;128. doi: 10.48101/ujms.v128.10281. eCollection 2023.ABSTRACTNitrous oxide, commonly known as 'laughing gas', has become a popular recreational drug. Whippets, small canisters containing gas in pressurized form, can be easily obtained from a food store. However, inhaling nitrous oxide from these canisters, which contain a 100% concentration, can lead to hypoxia, resulting in seizures or even death. Inhalation of nitrous oxide rarely causes pneumothorax, pneumomediastinum, and pneumopericardium. This case study highlights the potential dangers of recreational abuse of nitrous oxide.PMID:38084205 | ...
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Lee Ti Davidson Source Type: research

Vitamin D status in longstanding type 1 diabetes and controls. Association with upper extremity impairments
CONCLUSION: In patients with type 1 diabetes and a duration of 20 years or more, vitamin D level is not lower than in nondiabetic controls and is not associated with UEIs.PMID:38084202 | PMC:PMC10710851 | DOI:10.48101/ujms.v128.9888 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Hans J Arnqvist Per Leanderson Anna Sp ångeus Source Type: research

A light at the end of the tunnel - from mutation identification to a potential treatment for Alzheimer's disease
Ups J Med Sci. 2023 Nov 28;128. doi: 10.48101/ujms.v128.10316. eCollection 2023.ABSTRACTRecent advances have driven the development of immunotherapies that act by either promoting or suppressing a patient's immune system to treat inflammation, autoimmune disease, cardiovascular disease, infectious diseases, and several cancers. In addition, research conducted over the past 25 years has identified therapeutic targets and indicated that immunotherapy could be used to treat Alzheimer's disease (AD). Despite a number of setbacks, this approach has now led to the development of the first disease-modifying treatments for this de...
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Lars Lannfelt Source Type: research

Reference values of serum total IgE in Uppsala - comparison over four decades
CONCLUSION: The calculated ULN values were similar between the cohorts. We conclude that the total IgE reference values shown for Uppsala subjects from 1974 are still valid and suitable also for the ImmunoCAP Total IgE assay. The 100 kU/L threshold for total IgE had a low sensitivity but high specificity for atopy, asthma, and allergy.PMID:38084204 | PMC:PMC10710850 | DOI:10.48101/ujms.v128.9892 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Robert Mov érare Eilif Persson Andrei Malinovschi Christer Janson Source Type: research

Recreational use of nitrous oxide causes seizure, pneumothorax, pneumomediastinum, and pneumopericardium: nitrous oxide and its harm, a case report
Ups J Med Sci. 2023 Dec 8;128. doi: 10.48101/ujms.v128.10281. eCollection 2023.ABSTRACTNitrous oxide, commonly known as 'laughing gas', has become a popular recreational drug. Whippets, small canisters containing gas in pressurized form, can be easily obtained from a food store. However, inhaling nitrous oxide from these canisters, which contain a 100% concentration, can lead to hypoxia, resulting in seizures or even death. Inhalation of nitrous oxide rarely causes pneumothorax, pneumomediastinum, and pneumopericardium. This case study highlights the potential dangers of recreational abuse of nitrous oxide.PMID:38084205 | ...
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Lee Ti Davidson Source Type: research

Vitamin D status in longstanding type 1 diabetes and controls. Association with upper extremity impairments
CONCLUSION: In patients with type 1 diabetes and a duration of 20 years or more, vitamin D level is not lower than in nondiabetic controls and is not associated with UEIs.PMID:38084202 | PMC:PMC10710851 | DOI:10.48101/ujms.v128.9888 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Hans J Arnqvist Per Leanderson Anna Sp ångeus Source Type: research

A light at the end of the tunnel - from mutation identification to a potential treatment for Alzheimer's disease
Ups J Med Sci. 2023 Nov 28;128. doi: 10.48101/ujms.v128.10316. eCollection 2023.ABSTRACTRecent advances have driven the development of immunotherapies that act by either promoting or suppressing a patient's immune system to treat inflammation, autoimmune disease, cardiovascular disease, infectious diseases, and several cancers. In addition, research conducted over the past 25 years has identified therapeutic targets and indicated that immunotherapy could be used to treat Alzheimer's disease (AD). Despite a number of setbacks, this approach has now led to the development of the first disease-modifying treatments for this de...
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Lars Lannfelt Source Type: research

Reference values of serum total IgE in Uppsala - comparison over four decades
CONCLUSION: The calculated ULN values were similar between the cohorts. We conclude that the total IgE reference values shown for Uppsala subjects from 1974 are still valid and suitable also for the ImmunoCAP Total IgE assay. The 100 kU/L threshold for total IgE had a low sensitivity but high specificity for atopy, asthma, and allergy.PMID:38084204 | PMC:PMC10710850 | DOI:10.48101/ujms.v128.9892 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Robert Mov érare Eilif Persson Andrei Malinovschi Christer Janson Source Type: research

Recreational use of nitrous oxide causes seizure, pneumothorax, pneumomediastinum, and pneumopericardium: nitrous oxide and its harm, a case report
Ups J Med Sci. 2023 Dec 8;128. doi: 10.48101/ujms.v128.10281. eCollection 2023.ABSTRACTNitrous oxide, commonly known as 'laughing gas', has become a popular recreational drug. Whippets, small canisters containing gas in pressurized form, can be easily obtained from a food store. However, inhaling nitrous oxide from these canisters, which contain a 100% concentration, can lead to hypoxia, resulting in seizures or even death. Inhalation of nitrous oxide rarely causes pneumothorax, pneumomediastinum, and pneumopericardium. This case study highlights the potential dangers of recreational abuse of nitrous oxide.PMID:38084205 | ...
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Lee Ti Davidson Source Type: research

Vitamin D status in longstanding type 1 diabetes and controls. Association with upper extremity impairments
CONCLUSION: In patients with type 1 diabetes and a duration of 20 years or more, vitamin D level is not lower than in nondiabetic controls and is not associated with UEIs.PMID:38084202 | PMC:PMC10710851 | DOI:10.48101/ujms.v128.9888 (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - December 12, 2023 Category: General Medicine Authors: Hans J Arnqvist Per Leanderson Anna Sp ångeus Source Type: research