A cultural evolutionary model of the interaction between parental beliefs and behaviors, with applications to vaccine hesitancy
Theor Popul Biol. 2023 May 5:S0040-5809(23)00025-4. doi: 10.1016/j.tpb.2023.04.003. Online ahead of print.ABSTRACTHealth perceptions and health-related behaviors can change at the population level as cultures evolve. In the last decade, despite the proven efficacy of vaccines, the developed world has seen a resurgence of vaccine-preventable diseases (VPDs) such as measles, pertussis, and polio. Vaccine hesitancy, an individual attitude influenced by historical, political, and socio-cultural forces, is believed to be a primary factor responsible for decreasing vaccine coverage, thereby increasing the risk and occurrence of ...
Source: Theoretical Population Biology - May 7, 2023 Category: Biology Authors: Kerri-Ann Anderson Nicole Creanza Source Type: research

A cultural evolutionary model of the interaction between parental beliefs and behaviors, with applications to vaccine hesitancy
Theor Popul Biol. 2023 May 5:S0040-5809(23)00025-4. doi: 10.1016/j.tpb.2023.04.003. Online ahead of print.ABSTRACTHealth perceptions and health-related behaviors can change at the population level as cultures evolve. In the last decade, despite the proven efficacy of vaccines, the developed world has seen a resurgence of vaccine-preventable diseases (VPDs) such as measles, pertussis, and polio. Vaccine hesitancy, an individual attitude influenced by historical, political, and socio-cultural forces, is believed to be a primary factor responsible for decreasing vaccine coverage, thereby increasing the risk and occurrence of ...
Source: Theoretical Population Biology - May 7, 2023 Category: Biology Authors: Kerri-Ann Anderson Nicole Creanza Source Type: research

A cultural evolutionary model of the interaction between parental beliefs and behaviors, with applications to vaccine hesitancy
Theor Popul Biol. 2023 May 5:S0040-5809(23)00025-4. doi: 10.1016/j.tpb.2023.04.003. Online ahead of print.ABSTRACTHealth perceptions and health-related behaviors can change at the population level as cultures evolve. In the last decade, despite the proven efficacy of vaccines, the developed world has seen a resurgence of vaccine-preventable diseases (VPDs) such as measles, pertussis, and polio. Vaccine hesitancy, an individual attitude influenced by historical, political, and socio-cultural forces, is believed to be a primary factor responsible for decreasing vaccine coverage, thereby increasing the risk and occurrence of ...
Source: Theoretical Population Biology - May 7, 2023 Category: Biology Authors: Kerri-Ann Anderson Nicole Creanza Source Type: research

Waiting times in a branching process model of colorectal cancer initiation
Theor Popul Biol. 2023 Apr 24:S0040-5809(23)00023-0. doi: 10.1016/j.tpb.2023.04.001. Online ahead of print.ABSTRACTWe study a multi-stage model for the development of colorectal cancer from initially healthy tissue. The model incorporates a complex sequence of driver gene alterations, some of which result in immediate growth advantage, while others have initially neutral effects. We derive analytic estimates for the sizes of premalignant subpopulations, and use these results to compute the waiting times to premalignant and malignant genotypes. This work contributes to the quantitative understanding of colorectal tumor evol...
Source: Theoretical Population Biology - April 26, 2023 Category: Biology Authors: Ruibo Zhang Obinna A Ukogu Ivana Bozic Source Type: research

Waiting times in a branching process model of colorectal cancer initiation
Theor Popul Biol. 2023 Apr 24:S0040-5809(23)00023-0. doi: 10.1016/j.tpb.2023.04.001. Online ahead of print.ABSTRACTWe study a multi-stage model for the development of colorectal cancer from initially healthy tissue. The model incorporates a complex sequence of driver gene alterations, some of which result in immediate growth advantage, while others have initially neutral effects. We derive analytic estimates for the sizes of premalignant subpopulations, and use these results to compute the waiting times to premalignant and malignant genotypes. This work contributes to the quantitative understanding of colorectal tumor evol...
Source: Theoretical Population Biology - April 26, 2023 Category: Biology Authors: Ruibo Zhang Obinna A Ukogu Ivana Bozic Source Type: research