**A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection**

Theor Popul Biol. 2021 May 5:S0040-5809(21)00028-9. doi: 10.1016/j.tpb.2021.03.003. Online ahead of print.ABSTRACTIn this article, a biallelic reversible mutation model with linear and quadratic selection is analyzed. The approach reconnects to one proposed by Kimura (1979), who starts from a diffusion model and derives its equilibrium distribution up to a constant. We use a boundary-mutation Moran model, which approximates a general mutation model for small effective mutation rates, and derive its equilibrium distribution for polymorphic and monomorphic variants in small to moderately sized populations. Using this model, ...

**Source: **Theoretical Population Biology - May 8, 2021 **Category: **Biology **Authors: **Claus Vogl Lynette Caitlin Mikula **Source Type: **research

**A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection**

Theor Popul Biol. 2021 May 5:S0040-5809(21)00028-9. doi: 10.1016/j.tpb.2021.03.003. Online ahead of print.ABSTRACTIn this article, a biallelic reversible mutation model with linear and quadratic selection is analyzed. The approach reconnects to one proposed by Kimura (1979), who starts from a diffusion model and derives its equilibrium distribution up to a constant. We use a boundary-mutation Moran model, which approximates a general mutation model for small effective mutation rates, and derive its equilibrium distribution for polymorphic and monomorphic variants in small to moderately sized populations. Using this model, ...

**Source: **Theoretical Population Biology - May 8, 2021 **Category: **Biology **Authors: **Claus Vogl Lynette Caitlin Mikula **Source Type: **research

**A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection**

Theor Popul Biol. 2021 May 5:S0040-5809(21)00028-9. doi: 10.1016/j.tpb.2021.03.003. Online ahead of print.ABSTRACTIn this article, a biallelic reversible mutation model with linear and quadratic selection is analyzed. The approach reconnects to one proposed by Kimura (1979), who starts from a diffusion model and derives its equilibrium distribution up to a constant. We use a boundary-mutation Moran model, which approximates a general mutation model for small effective mutation rates, and derive its equilibrium distribution for polymorphic and monomorphic variants in small to moderately sized populations. Using this model, ...

**Source: **Theoretical Population Biology - May 8, 2021 **Category: **Biology **Authors: **Claus Vogl Lynette Caitlin Mikula **Source Type: **research

**A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection**

Theor Popul Biol. 2021 May 5:S0040-5809(21)00028-9. doi: 10.1016/j.tpb.2021.03.003. Online ahead of print.ABSTRACTIn this article, a biallelic reversible mutation model with linear and quadratic selection is analyzed. The approach reconnects to one proposed by Kimura (1979), who starts from a diffusion model and derives its equilibrium distribution up to a constant. We use a boundary-mutation Moran model, which approximates a general mutation model for small effective mutation rates, and derive its equilibrium distribution for polymorphic and monomorphic variants in small to moderately sized populations. Using this model, ...

**Source: **Theoretical Population Biology - May 8, 2021 **Category: **Biology **Authors: **Claus Vogl Lynette Caitlin Mikula **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**The effect of consanguinity on coalescence times on the X chromosome**

We describe a consanguinity effect on X-chromosomal TMRCA that differs from the autosomal pattern under matrilateral but not under patrilateral first-cousin mating. For matrilateral first cousins, the effect of consanguinity in reducing TMRCA is stronger on the X chromosome than on the autosomes, with an increased effect of parallel-cousin mating compared to cross-cousin mating. The theoretical computations support the utility of the model in understanding patterns of genomic sharing on the X chromosome.PMID:33901539 | DOI:10.1016/j.tpb.2021.03.004 (Source: Theoretical Population Biology)

**Source: **Theoretical Population Biology - April 26, 2021 **Category: **Biology **Authors: **Daniel J Cotter Alissa L Severson Noah A Rosenberg **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-Malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the resource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the ch...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the ressource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the c...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the ressource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the c...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the ressource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the c...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the ressource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the c...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the ressource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the c...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the ressource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the c...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Model of neo-malthusian population anticipating future changes in resources**

Theor Popul Biol. 2021 Mar 29:S0040-5809(21)00019-8. doi: 10.1016/j.tpb.2021.03.002. Online ahead of print.ABSTRACTIn this paper we develop a class of models to study a population and resource dynamical system in which the decision to give birth is based on a rational far-sighted cost-benefit analysis on what the future of the ressource level will be. This leads to consider a system in which a time forward population/resource dynamical system is coupled with a time backward Bellman's equation (which models the choice of having a child). We construct, from a population model with food consumption, an example, to study the c...

**Source: **Theoretical Population Biology - April 1, 2021 **Category: **Biology **Authors: **Philippe Michel **Source Type: **research

**Inference of gene flow in the process of speciation: Efficient maximum-likelihood implementation of a generalised isolation-with-migration model**

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

**Inference of gene flow in the process of speciation: Efficient maximum-likelihood implementation of a generalised isolation-with-migration model**

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

**Inference of gene flow in the process of speciation: Efficient maximum-likelihood implementation of a generalised isolation-with-migration model**

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

Theor Popul Biol. 2021 Mar 15:S0040-5809(21)00018-6. doi: 10.1016/j.tpb.2021.03.001. Online ahead of print.ABSTRACTThe 'isolation with migration' (IM) model has been extensively used in the literature to detect gene flow during the process of speciation. In this model, an ancestral population split into two or more descendant populations which subsequently exchanged migrants at a constant rate until the present. Of course, the assumption of constant gene flow until the present is often over-simplistic in the context of speciation. In this paper, we consider a 'generalised IM' (GIM) model: a two-population IM model in which...

**Source: **Theoretical Population Biology - March 19, 2021 **Category: **Biology **Authors: **Rui J Costa Hilde M Wilkinson-Herbots **Source Type: **research

**Variance and limiting distribution of coalescence times in a diploid model of a consanguineous population**

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research

**Variance and limiting distribution of coalescence times in a diploid model of a consanguineous population**

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research

**Variance and limiting distribution of coalescence times in a diploid model of a consanguineous population**

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research

Theor Popul Biol. 2021 Mar 3:S0040-5809(21)00017-4. doi: 10.1016/j.tpb.2021.02.002. Online ahead of print.ABSTRACTRecent modeling studies interested in runs of homozygosity (ROH) and identity by descent (IBD) have sought to connect these properties of genomic sharing to pairwise coalescence times. Here, we examine a variety of features of pairwise coalescence times in models that consider consanguinity. In particular, we extend a recent diploid analysis of mean coalescence times for lineage pairs within and between individuals in a consanguineous population to derive the variance of coalescence times, studying its dependen...

**Source: **Theoretical Population Biology - March 6, 2021 **Category: **Biology **Authors: **Alissa L Severson Shai Carmi Noah A Rosenberg **Source Type: **research