Dynamic Pressure Stimulation Upregulates Collagen II and Aggrecan in Nucleus Pulposus Cells Through Calcium Signaling
Conclusion.
The results link mechanotransduction to the downstream ECM protein synthesis and suggest slow exercises that correspond with spontaneous calcium oscillations in NP cells can be effective to stimulate ECM synthesis in IVD. (Source: Spine)
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Biomechanics Source Type: research
Biomechanical Effects of Thoracolumbosacral Orthosis Design Features on 3D Correction in Adolescent Idiopathic Scoliosis: A Comprehensive Multicenter Study
Conclusions.
The corrective features of various scoliosis braces were objectively compared in a systematic approach with minimal biases and variability in test parameters, providing a better biomechanical understanding of individual passive mechanisms’ contribution to 3D correction. (Source: Spine)
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Biomechanics Source Type: research
The Impact of Spinopelvic Parameters on Hip Degeneration After Spinal Fusion
Conclusion.
The PI, SS, and PI-LL were associated with the progression of hip joint narrowing after spinal fusion, especially after fusion of four or more levels. Surgeons need to be aware of the risk of increased hip joint narrowing in patients with a large PI, SS, and PI-LL after fusion surgery. (Source: Spine)
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Clinical Case Series Source Type: research
The Antepsoas (ATP) Surgical Corridor for Lumbar and Lumbosacral Arthrodesis: A Radiographic, Anatomic, and Surgical Investigation
Study Design.
Retrospective review of prospectively collected data.
Objective.
To investigate the size of prepsoas surgical corridors, developed between the iliopsoas and prespinal vessels, at all disk levels between L1 and S1 granted by left and right lateral antepsoas (ATP) approaches. Secondary aims include evaluation of presurgery radiographic prepsoas windows between L1 and S1 with respect to the intraoperative findings.
Summary of Background Data.
The ATP technique is an evolving alternative to the transpsoas and direct anterior exposures for lumbar fusion. However, the vascular morphometric data of...
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Anatomy Source Type: research
Clinical Indicators of Surgical Outcomes After Laminoplasty for Patients With Cervical Ossification of the Posterior Longitudinal Ligament: A Prospective Multicenter Study
This study aims to evaluate patient-reported outcomes using the Japanese Orthopedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ) and clarify clinical factors that affect the therapeutic effects for patients with cervical ossification of the posterior longitudinal ligament (OPLL).
Summary of Background Data.
Although previous studies identified factors that affected the surgical outcomes, their assessment was mainly based on the Japanese Orthopedic Association score, which only includes neurological function. Investigating this pathology through multiple functions and quality of life (QOL) is pi...
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Cervical Spine Source Type: research
Proposal for a Treatment-oriented Classification System for Congenital Kyphosis in Children
Conclusion.
The proposed classification system provides clear descriptions and surgical options for various types of pediatric congenital kyphotic deformities. The reliability study confirmed that the classification system is both simple and consistent, although further research may be needed to validate the system. (Source: Spine)
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Deformity Source Type: research
3D Radiological Outcomes and Quality of Life of Patients With Moderate Idiopathic Scoliosis Treated With Anterior Vertebral Growth Modulation Versus Bracing: Two-Year Follow-up
Conclusion.
Even though these two cohorts are not fully comparable, bracing seems to control progression for a significant portion of patients with moderate scoliosis curves, while AVBGM significantly corrected and maintained 3D deformity parameters at 2-year follow-up. (Source: Spine)
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Deformity Source Type: research
The Outcome Horizon Is Optimistic After Infection: Commentary on “Clinical Outcomes at 1 Year Follow-up for Patients With Surgical Site Infection After Spinal Fusion”
No abstract available (Source: Spine)
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Commentary Source Type: research
Clinical Outcomes at One-year Follow-up for Patients With Surgical Site Infection After Spinal Fusion
Study Design.
Retrospective case-control study.
Objective.
To compare health-related quality of life outcomes at one-year follow-up between patients who did and did not develop surgical site infection (SSI) after thoracolumbar spinal fusion.
Summary of Background Data.
SSI is among the most common healthcare-associated complications. As healthcare systems increasingly emphasize the value of delivered care, there is an increased need to understand the clinical impact of SSIs.
Materials and Methods.
A retrospective 3:1 (control:SSI) propensity-matched case-control study was conducted for adult patien...
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Surgery Source Type: research
Prospective, Randomized, Blinded Clinical Trial Comparing PEEK and Allograft Spacers in Patients Undergoing Anterior Cervical Discectomy and Fusion Surgeries
Conclusion.
Comparable radiographic outcomes were observed for patients undergoing one- to three-level PEEK versus allograft-assisted ACDF surgeries. Although MCID comparisons suggest that allograft and PEEK-treated patients have similar clinical outcomes, testing that incorporates the magnitude of the change suggests that there may be a statistically significant greater magnitude of improvement for the allograft group patients, but further studies with a larger sample size would be helpful to determine if a true effect exists. (Source: Spine)
Source: Spine - July 28, 2022 Category: Orthopaedics Tags: Randomized Trial Source Type: research
Factors Associated with Thickening of the Ligamentum Flavum on Magnetic Resonance Imaging in Patients with Lumbar Spinal Canal Stenosis
Conclusion.
In patients with LSCS, thickening of the LF on MRI appears to represent tissue hypertrophy. The association between the thickness of the LF on MRI and age, disc degeneration, and disc level may indicate simultaneous alterations of spine components along with aging that was cancelled by the effects of haemodialysis. (Source: Spine)
Source: Spine - July 13, 2022 Category: Orthopaedics Tags: Basic Science Source Type: research
Three-dimensional Printing of Biomimetic Titanium Mimicking Trabecular Bone Induces Human Mesenchymal Stem Cell Proliferation: An In-vitro Analysis
Conclusion.
3D-pTi provides a scaffold for bone formation that structurally mimics cancellous bone and improves hMSC adhesion and proliferation compared to 2D-Ti and PEEK. (Source: Spine)
Source: Spine - July 13, 2022 Category: Orthopaedics Tags: Basic Science Source Type: research
Formal Patient Complaints and Malpractice Events Involving Orthopedic Spine Surgeons: A Ten-Year Analysis
Study Design.
Case-control study.
Objective.
To analyze patient complaints, potential risk, and malpractice events involving orthopedic spine surgeons over a 10-year period.
Summary of Background Data.
Unsolicited patient complaints may be associated with risk management and malpractice events.
Methods.
We analyzed patient complaint, potential risk event, and malpractice event data for six orthopedic spine surgeons over a 10-year period. Patient complaints were analyzed and classified according to the Patient Complaint Analysis System. Baseline demographics were recorded for patients with complaint...
Source: Spine - July 13, 2022 Category: Orthopaedics Tags: Clinical Case Series Source Type: research
Transcranial Motor-evoked Potential Alert After Supine-to-Prone Position Change During Thoracic Ossification in Posterior Longitudinal Ligament Surgery: A Prospective Multicenter Study of the Monitoring Committee of the Japanese Society for Spine Surgery and Related Research
Conclusion.
Tc-MEP alert during position change is an important sign of spinal cord injury due to alignment change at the upper thoracic spine. Tc-MEP monitoring before supine-to-prone position change was necessary to prevent spinal cord injury in surgeries for T-OPLL. (Source: Spine)
Source: Spine - July 13, 2022 Category: Orthopaedics Tags: Clinical Case Series Source Type: research
Emergency Department Visits After Outpatient Spine Surgery
This study sought to characterize the incidence and timing of postoperative emergency department (ED) visits after common outpatient spinal surgeries performed at ambulatory surgery centers (ASCs) and at hospital outpatient departments (HOPDs).
Summary of Background Data.
Outpatient spine surgery has markedly grown in popularity over the past decade. The incidence of ED visits after outpatient spine surgery is not well established.
Methods.
This study was a retrospective analysis of a large commercial claims insurance database of patients 65 years old and below. Patients who underwent single-level anterior ce...
Source: Spine - July 13, 2022 Category: Orthopaedics Tags: Health Services Research Source Type: research
