Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state
RNA. 2023 Sep 20:rna.079625.123. doi: 10.1261/rna.079625.123. Online ahead of print.ABSTRACTTrypanosoma brucei occupies distinct niches throughout its life cycle, within both the mammalian and tsetse fly hosts. The immunological and biochemical complexity and variability of each of these environments require a reshaping of the protein landscape of the parasite both to evade surveillance and face changing metabolic demands. In kinetoplastid protozoa, including T. brucei, post-transcriptional control mechanisms are the primary means of gene regulation, and these are often mediated by RNA-binding proteins. DRBD18 is a T. bruc...
Source: RNA - September 20, 2023 Category: Genetics & Stem Cells Authors: Martin Ciganda Jose Sotelo-Silveira Ashutosh P Dubey Parul Pandey Joseph T Smith Shichen Shen Jun Qu Pablo Smircich Laurie K Read Source Type: research

Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state
RNA. 2023 Sep 20:rna.079625.123. doi: 10.1261/rna.079625.123. Online ahead of print.ABSTRACTTrypanosoma brucei occupies distinct niches throughout its life cycle, within both the mammalian and tsetse fly hosts. The immunological and biochemical complexity and variability of each of these environments require a reshaping of the protein landscape of the parasite both to evade surveillance and face changing metabolic demands. In kinetoplastid protozoa, including T. brucei, post-transcriptional control mechanisms are the primary means of gene regulation, and these are often mediated by RNA-binding proteins. DRBD18 is a T. bruc...
Source: RNA - September 20, 2023 Category: Genetics & Stem Cells Authors: Martin Ciganda Jose Sotelo-Silveira Ashutosh P Dubey Parul Pandey Joseph T Smith Shichen Shen Jun Qu Pablo Smircich Laurie K Read Source Type: research

Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state
RNA. 2023 Sep 20:rna.079625.123. doi: 10.1261/rna.079625.123. Online ahead of print.ABSTRACTTrypanosoma brucei occupies distinct niches throughout its life cycle, within both the mammalian and tsetse fly hosts. The immunological and biochemical complexity and variability of each of these environments require a reshaping of the protein landscape of the parasite both to evade surveillance and face changing metabolic demands. In kinetoplastid protozoa, including T. brucei, post-transcriptional control mechanisms are the primary means of gene regulation, and these are often mediated by RNA-binding proteins. DRBD18 is a T. bruc...
Source: RNA - September 20, 2023 Category: Genetics & Stem Cells Authors: Martin Ciganda Jose Sotelo-Silveira Ashutosh P Dubey Parul Pandey Joseph T Smith Shichen Shen Jun Qu Pablo Smircich Laurie K Read Source Type: research

Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state
RNA. 2023 Sep 20:rna.079625.123. doi: 10.1261/rna.079625.123. Online ahead of print.ABSTRACTTrypanosoma brucei occupies distinct niches throughout its life cycle, within both the mammalian and tsetse fly hosts. The immunological and biochemical complexity and variability of each of these environments require a reshaping of the protein landscape of the parasite both to evade surveillance and face changing metabolic demands. In kinetoplastid protozoa, including T. brucei, post-transcriptional control mechanisms are the primary means of gene regulation, and these are often mediated by RNA-binding proteins. DRBD18 is a T. bruc...
Source: RNA - September 20, 2023 Category: Genetics & Stem Cells Authors: Martin Ciganda Jose Sotelo-Silveira Ashutosh P Dubey Parul Pandey Joseph T Smith Shichen Shen Jun Qu Pablo Smircich Laurie K Read Source Type: research

Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state
RNA. 2023 Sep 20:rna.079625.123. doi: 10.1261/rna.079625.123. Online ahead of print.ABSTRACTTrypanosoma brucei occupies distinct niches throughout its life cycle, within both the mammalian and tsetse fly hosts. The immunological and biochemical complexity and variability of each of these environments require a reshaping of the protein landscape of the parasite both to evade surveillance and face changing metabolic demands. In kinetoplastid protozoa, including T. brucei, post-transcriptional control mechanisms are the primary means of gene regulation, and these are often mediated by RNA-binding proteins. DRBD18 is a T. bruc...
Source: RNA - September 20, 2023 Category: Genetics & Stem Cells Authors: Martin Ciganda Jose Sotelo-Silveira Ashutosh P Dubey Parul Pandey Joseph T Smith Shichen Shen Jun Qu Pablo Smircich Laurie K Read Source Type: research