Estrogen-sensitive activation of SGK1 induces M2 macrophages with anti-inflammatory properties and a Th2 response at the maternal –fetal interface
Decidual macrophages participate in immune regulation at the maternal –fetal interface. Abnormal M1/M2 polarization of decidual macrophages might predispose immune maladaptation in recurrent pregnancy loss (RPL... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 24, 2023 Category: Endocrinology Authors: Yiyun Lou, Zhujing Fu, Ye Tian, Minhao Hu, Qijing Wang, Yuanyuan Zhou, Ning Wang, Qin Zhang and Fan Jin Tags: Research Source Type: research

How much obesity and diabetes do impair male fertility?
Subfertility in obese and diabetic men during the reproductive age is evident, but the mechanisms by which obesity and diabetes mellitus cause male infertility are not entirely understood. The current study aimed... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 19, 2023 Category: Endocrinology Authors: Shima AbbasiHormozi, Azam Kouhkan, Abdolhossein Shahverdi, Amir Parikar, Azin Shirin and Samira Vesali Tags: Research Source Type: research

Artificial ovaries constructed from biodegradable chitin-based hydrogels with the ability to restore ovarian endocrine function and alleviate osteoporosis in ovariectomized mice
Artificial ovary (AO) is an alternative approach to provide physiological hormone to post-menopausal women. The therapeutic effects of AO constructed using alginate (ALG) hydrogels are limited by their low ang... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 19, 2023 Category: Endocrinology Authors: Du Xiang, Encheng Zhou, Mei Wang, Kan Wang, Shujun Zhou, Qing Ma, Zibiao Zhong, Qifa Ye, Yun Chen, Xiaoli Fan and Yanfeng Wang Tags: Research Source Type: research

Interindividual variation of progesterone elevation post LH rise: implications for natural cycle frozen embryo transfers in the individualized medicine era
The key to optimal timing of frozen embryo transfer (FET ) is to synchronize the embryo with the receptive phase of the endometrium. Secretory transformation of the endometrium is induced by progesterone. In c... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 18, 2023 Category: Endocrinology Authors: Carol Coughlan, Baris Ata, Raquel Del Gallego, Barbara Lawrenz, Laura Melado, Suzan Samir and Human Fatemi Tags: Research Source Type: research

Live birth rates following individualized dosing algorithm of follitropin delta in a long GnRH agonist protocol
To explore the efficacy and safety of individualized follitropin delta dosing, based on serum anti-M üllerian hormone (AMH) concentration and bodyweight, in a long gonadotropin-releasing hormone (GnRH) agonist ... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 16, 2023 Category: Endocrinology Authors: Manuel Fern ández Sánchez, Per Larsson, Marcos Ferrando Serrano, Ernesto Bosch, Juan Antonio García Velasco, Esther Santamaría López and Bernadette Mannaerts Tags: Research Source Type: research

Sohlh1 and Lhx8 are prominent biomarkers to estimate the primordial follicle pool in mice
Efficient evaluation of the primordial follicle pool (PFP) of mammalian models is an essential subject in biomedical research relating to ovarian physiology and pathogenesis. Our recent study has identified a ... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 16, 2023 Category: Endocrinology Authors: Li Liu, Biting Liu, Lian Wang, Caixia Li, Yang Zhou, Jihui Zhu, Jinye Ding, Shupeng Liu and Zhongping Cheng Tags: Research Source Type: research

Analysis of the quality, accuracy, and readability of patient information on polycystic ovarian syndrome (PCOS) on the internet available in English: a cross-sectional study
Online information about PCOS lacks reliability for patients seeking information about the disease. Thus, we aimed to perform an updated analysis of the quality, accuracy, and readability of patient informatio... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 15, 2023 Category: Endocrinology Authors: Helene V ågenes and Shelly Melissa Pranić Tags: Research Source Type: research

Stress and polycystic ovarian morphology in functional hypothalamic amenorrhea: a retrospective cohort study
Women with functional hypothalamic amenorrhea (FHA) reveal polycystic ovarian morphology (PCOM) in up to 50%. If stress sensitivity in women with polycystic ovary syndrome (PCOS) is the reason why PCOS women a... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 11, 2023 Category: Endocrinology Authors: Marlene Hager, Didier Dewailly, Rodrig Marculescu, Stefan Ghobrial, John Preston Parry and Johannes Ott Tags: Research Source Type: research

PIK3CA mutation in endometriotic epithelial cells promotes viperin-dependent inflammatory response to insulin
Endometrial epithelia are known to harbor cancer driver mutations in the absence of any pathologies, including mutations in PIK3CA. Insulin plays an important role in regulating uterine metabolism during pregn... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 11, 2023 Category: Endocrinology Authors: Mike R. Wilson, Shannon Harkins, Jake J. Reske, Rebecca A. Siwicki, Marie Adams, Victoria L. Bae-Jump, Jose M. Teixeira and Ronald L. Chandler Tags: Research Source Type: research

Advanced glycation end-products and its soluble receptor are not independent predictors of incident dysglycaemia or metabolic syndrome in women with polycystic ovary syndrome: a prospective observational study
To evaluate the association of serum advanced glycation end-products (AGEs) and its soluble receptor of AGE (sRAGE) levels with dysglycaemia and metabolic syndrome in women with polycystic ovary syndrome (PCOS). (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - May 10, 2023 Category: Endocrinology Authors: Yu Wing Tong, Jennifer Ka Yee Ko, Karen Siu Ling Lam, Sidney Tam, Vivian Chi Yan Lee, Pak Chung Ho, Ernest Hung Yu Ng and Raymond Hang Wun Li Tags: Research Source Type: research

Sperm-borne microRNA-34c regulates maternal mRNA degradation and preimplantation embryonic development in mice
Studies have shown that sperm-borne microRNAs (miRNAs) are involved in mammalian preimplantation embryonic development. In humans, spermatozoan miR-34c levels are correlated with in vitro fertilization outcomes, ... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - April 26, 2023 Category: Endocrinology Authors: Long Cui, Li Fang, Lili Zhuang, Biwei Shi, Chao-Po Lin and Yinghui Ye Tags: Research Source Type: research

Human papillomavirus infection in women undergoing in-vitro fertilization: effects on embryo development kinetics and live birth rate
Several studies showed that human papillomavirus (HPV) affects male fertility, but its impact on female fertility and in vitro fertilization (IVF) outcome is not yet clear. (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - April 24, 2023 Category: Endocrinology Authors: Federica Zullo, Valentina Fiano, Anna Gillio-Tos, Sara Leoncini, Ginevra Nesi, Luigia Macr ì, Mario Preti, Alessandro Rolfo, Chiara Benedetto, Alberto Revelli and Laura De Marco Tags: Research Source Type: research

The emerging role of lysine succinylation in ovarian aging
Ovarian aging is a process of decline in its reserve leading to ovary dysfunction and even reduced health quality in offspring. However, aging-related molecular pathways in the ovary remain obscure. Lysine suc... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - April 20, 2023 Category: Endocrinology Authors: Meiling Le, Jia Li, Dalei Zhang, Yuan Yuan, Chong Zhou, Jinxia He, Jian Huang, Liaoliao Hu, Tao Luo and Liping Zheng Tags: Research Source Type: research

Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2
Early embryo implantation is a complex phenomenon characterized by the presence of an implantation-competent blastocyst and a receptive endometrium. Embryo development and endometrial receptivity must be synch... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - April 15, 2023 Category: Endocrinology Authors: Aur élie Hennes, Johanna Devroe, Katrien De Clercq, Martina Ciprietti, Katharina Held, Katrien Luyten, Nele Van Ranst, Nina Maenhoudt, Karen Peeraer, Hugo Vankelecom, Thomas Voets and Joris Vriens Tags: Research Source Type: research

RA-RAR signaling promotes mouse vaginal opening through increasing β-catenin expression and vaginal epithelial cell apoptosis
Retinoic acid (RA) plays important role in the maintenance and differentiation of the M üllerian ducts during the embryonic stage via RA receptors (RARs). However, the function and mechanism of RA-RAR signaling... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - April 11, 2023 Category: Endocrinology Authors: Nana Zheng, Wenbo Zhang, Xiaodan Zhang, Biao Li, Zhanying Wu, Yashuang Weng, Weiyong Wang, Jingjing Miao, Jing Yang, Meijia Zhang and Wei Xia Tags: Research Source Type: research