Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia
This study aimed to determine the... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 22, 2022 Category: Endocrinology Authors: Xiaoxiao Han, Lin Hao, Zhenduo Shi, Ying Li, Liang Wang, Zhenbei Li, Qiang Zhang, Fangfang Hu, Yijuan Cao, Kun Pang and Zuobin Zhu Tags: Research Source Type: research

Protective effect of melatonin on alleviating early oxidative stress induced by DOX in mice spermatogenesis and sperm quality maintaining
Doxorubicin (DOX) is an effective chemotherapy drug, but its clinical use has adverse effects on male reproduction. However, there are few studies about the specific biological processes related to male reprod... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 18, 2022 Category: Endocrinology Authors: Teng Zi, YaNan Liu, YuSheng Zhang, ZeLin Wang, ZhiXin Wang, Song Zhan, Zhu Peng, Ning Li, XueXia Liu and FuJun Liu Tags: Research Source Type: research

Diverse actions of sirtuin-1 on ovulatory genes and cell death pathways in human granulosa cells
Human granulosa-lutein cells (hGLCs) amply express sirtuin-1 (SIRT1), a NAD  + -dependent deacetylase that is associated with various cellular functions. SIRT1 was shown to elevate cAMP on its own and additivel... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 15, 2022 Category: Endocrinology Authors: Jackson Sapuleni, Magdalena Szymanska and Rina Meidan Tags: Research Source Type: research

IGF2 reduces meiotic defects in oocytes from obese mice and improves embryonic developmental competency
Maternal obesity is a global issue that has devastating effects across the reproductive spectrum such as meiotic defects in oocytes, consequently worsening pregnancy outcomes. Different studies have shown that... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 14, 2022 Category: Endocrinology Authors: Yanling Wan, Tahir Muhammad, Tao Huang, Yue Lv, Qianqian Sha, Shuang Yang, Gang Lu, Wai-yee Chan, Jinlong Ma and Hongbin Liu Tags: Research Source Type: research

16 years follow-up evaluation of immediate vs delayed vs. combined hormonal therapy on fertility of patients with cryptorchidism: results of a longitudinal cohort study
To investigate in a longitudinal cohort study, the best treatment to preserve fertility in cryptorchid subjects. Patients treated with immediate hormonal vs. delayed vs. combined (hormone plus surgery) therapy... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 14, 2022 Category: Endocrinology Authors: Riccardo Bartoletti, Antonio Luigi Pastore, Filippo Menchini Fabris, Tommaso Di Vico, Riccardo Morganti, Andrea Mogorovich, Girolamo Morelli, Diego Peroni, Yazan Al Salhi and Alessandro Zucchi Tags: Research Source Type: research

A loss-of-function variant in SSFA2 causes male infertility with globozoospermia and failed oocyte activation
Globozoospermia (OMIM: 102530) is a rare type of teratozoospermia ( (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 14, 2022 Category: Endocrinology Authors: Gelin Huang, Xueguang Zhang, Guanping Yao, Lin Huang, Sixian Wu, Xiaoliang Li, Juncen Guo, Yuting Wen, Yan Wang, Lijun Shang, Na Li and Wenming Xu Tags: Correspondence Source Type: research

The expression of IGFBP-5 in the reproductive axis and effect on the onset of puberty in female rats
Insulin-like growth factor-binding protein-5 (IGFBP-5) has recently been shown to alter the reproductive capacity by regulating insulin-like growth factor (IGF) bioavailability or IGF-independent effects. The ... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 12, 2022 Category: Endocrinology Authors: Zhiqiu Yao, Maosen Lin, Tao Lin, Xinbao Gong, Pin Qin, Hailing Li, Tiezhu Kang, Jing Ye, Yanyun Zhu, Qiwen Hong, Ya Liu, Yunsheng Li, Juhua Wang and Fugui Fang Tags: Research Source Type: research

Regulatory roles of alternative splicing at Ezh2 gene in mouse oocytes
Enhancer of zeste homologue 2 (EZH2), the core member of polycomb repressive complex 2 (PRC2), has multiple splicing modes and performs various physiological functions. However, function and mechanism of alte... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 5, 2022 Category: Endocrinology Authors: Shi-meng Guo, Xing-ping Liu, Qing Tian, Cai-feng Fei, Yi-ran Zhang, Zhi-ming Li, Ying Yin, Ximiao He and Li-quan Zhou Tags: Research Source Type: research

Basal and dynamic relationships between serum anti-M üllerian hormone and gonadotropins in patients with functional hypothalamic amenorrhea, with or without polycystic ovarian morphology
To evaluate in women with functional hypothalamic amenorrhea (FHA), whether there is a difference between patients with and without polycystic ovarian morphology (PCOM) concerning the response to a gonadotropi... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 4, 2022 Category: Endocrinology Authors: Marlene Hager, Johannes Ott, Julian Marschalek, Marie-Louise Marschalek, Clemens Kinsky, Rodrig Marculescu and Didier Dewailly Tags: Research Source Type: research

Myostatin: a multifunctional role in human female reproduction and fertility – a short review
Myostatin (MSTN) is member of the transforming growth factor β (TGF-β) superfamily and was originally identified in the musculoskeletal system as a negative regulator of skeletal muscle growth. The functional ... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 2, 2022 Category: Endocrinology Authors: Sijia Wang, Lanlan Fang, Luping Cong, Jacqueline Pui Wah Chung, Tin Chiu Li and David Yiu Leung Chan Tags: Review Source Type: research

Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis
Follicle-stimulating hormone signaling is essential for the initiation and early stages of spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli cells. As the only type of ... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - July 2, 2022 Category: Endocrinology Authors: Jia-Ming Wang, Zhen-Fang Li, Wan-Xi Yang and Fu-Qing Tan Tags: Review Source Type: research

The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis
Ovulation is regulated by extracellular signal-regulated kinase-1 (ERK-1) and ERK-2 signaling mechanisms, and ERK-1/2 kinases modulates the function of most of the LH-regulated genes. Defective ERK kinase sign... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - June 29, 2022 Category: Endocrinology Authors: Gurhan Guney, Mine Islimye Ta şkın, Nazli Sener, Ezgi Tolu, Yavuz Dodurga, Levent Elmas, Orkun Cetin and Cengiz Sarigul Tags: Research Source Type: research

Endometrial thickness is an independent risk factor of hypertensive disorders of pregnancy: a retrospective study of 13,458 patients in frozen-thawed embryo transfers
Hypertensive disorders of pregnancy (HDP) are an important cause of maternal and fetal mortality, and its potential risk factors are still being explored. Endometrial thickness (EMT), as one of the important m... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - June 28, 2022 Category: Endocrinology Authors: Meng Zhang, Jing Li, Xiao Fu, Yiting Zhang, Tao Zhang, Bingjie Wu, Xinyue Han and Shanshan Gao Tags: Research Source Type: research

Do oral combined contraceptive pills modify body image and sexual function?
The effect of hormonal contraceptives on sexual function and body image is still controversial. Existing studies have not come to definite conclusions on the association between hormonal contraceptive use and ... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - June 28, 2022 Category: Endocrinology Authors: Krzysztof Nowosielski Tags: Research Source Type: research

Dose –response association between maternal pre-pregnancy bodyweight and gestational diabetes mellitus following ART treatment: a population-based cohort study
The impact of maternal pre-pregnancy bodyweight on gestational diabetes mellitus (GDM) following assisted reproductive technology (ART) treatment has been insufficiently investigated. The aim of this study was... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - June 22, 2022 Category: Endocrinology Authors: Yiquan Xiong, Jing Wang, Yana Qi, Chunrong Liu, Mingxi Li, Guanhua Yao, Wei Sun, Yongyao Qian, Lishan Ye, Hui Liu, Qiushi Xu, Kang Zou, Jing Tan and Xin Sun Tags: Research Source Type: research