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Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Classical cadherins in the testis: how are they regulated?
Reprod Fertil Dev. 2023 Sep 18. doi: 10.1071/RD23084. Online ahead of print.ABSTRACTCadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli and germ cells in rodents, CDH1 is primarily detected in undifferentiated spermatogonia. As for CDH3, its expression is mainly fo...
Source: Reproduction, Fertility, and Development - September 17, 2023 Category: Reproduction Medicine Authors: Ha Tuyen Nguyen Luc J Martin Source Type: research

Use of sensitivity-enhanced nuclear magnetic resonance spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe in identifying human sperm intracellular metabolites
CONCLUSIONS: Sensitivity-enhanced NMR spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe is a potential tool for identifying intracellular metabolites when sperm number is low.IMPLICATIONS: Use of sensitivity-enhanced NMR spectroscopy opens up the opportunity to test for endogenous metabolites in samples with a limited number of spermatozoa, to understand the patho-physiology of infertility.PMID:37643634 | DOI:10.1071/RD22246 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - August 29, 2023 Category: Reproduction Medicine Authors: Aswathi Cheredath Shubhashree Uppangala Ameya Jijo R Vani Lakshmi G A Nagana Gowda Guruprasad Kalthur Satish Kumar Adiga Source Type: research

Use of sensitivity-enhanced nuclear magnetic resonance spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe in identifying human sperm intracellular metabolites
CONCLUSIONS: Sensitivity-enhanced NMR spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe is a potential tool for identifying intracellular metabolites when sperm number is low.IMPLICATIONS: Use of sensitivity-enhanced NMR spectroscopy opens up the opportunity to test for endogenous metabolites in samples with a limited number of spermatozoa, to understand the patho-physiology of infertility.PMID:37643634 | DOI:10.1071/RD22246 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - August 29, 2023 Category: Reproduction Medicine Authors: Aswathi Cheredath Shubhashree Uppangala Ameya Jijo R Vani Lakshmi G A Nagana Gowda Guruprasad Kalthur Satish Kumar Adiga Source Type: research

Use of sensitivity-enhanced nuclear magnetic resonance spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe in identifying human sperm intracellular metabolites
CONCLUSIONS: Sensitivity-enhanced NMR spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe is a potential tool for identifying intracellular metabolites when sperm number is low.IMPLICATIONS: Use of sensitivity-enhanced NMR spectroscopy opens up the opportunity to test for endogenous metabolites in samples with a limited number of spermatozoa, to understand the patho-physiology of infertility.PMID:37643634 | DOI:10.1071/RD22246 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - August 29, 2023 Category: Reproduction Medicine Authors: Aswathi Cheredath Shubhashree Uppangala Ameya Jijo R Vani Lakshmi G A Nagana Gowda Guruprasad Kalthur Satish Kumar Adiga Source Type: research

Use of sensitivity-enhanced nuclear magnetic resonance spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe in identifying human sperm intracellular metabolites
CONCLUSIONS: Sensitivity-enhanced NMR spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe is a potential tool for identifying intracellular metabolites when sperm number is low.IMPLICATIONS: Use of sensitivity-enhanced NMR spectroscopy opens up the opportunity to test for endogenous metabolites in samples with a limited number of spermatozoa, to understand the patho-physiology of infertility.PMID:37643634 | DOI:10.1071/RD22246 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - August 29, 2023 Category: Reproduction Medicine Authors: Aswathi Cheredath Shubhashree Uppangala Ameya Jijo R Vani Lakshmi G A Nagana Gowda Guruprasad Kalthur Satish Kumar Adiga Source Type: research