Use of sensitivity-enhanced nuclear magnetic resonance spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe in identifying human sperm intracellular metabolites

CONCLUSIONS: Sensitivity-enhanced NMR spectroscopy equipped with a 1.7-mm cryogenically cooled micro-coil probe is a potential tool for identifying intracellular metabolites when sperm number is low.IMPLICATIONS: Use of sensitivity-enhanced NMR spectroscopy opens up the opportunity to test for endogenous metabolites in samples with a limited number of spermatozoa, to understand the patho-physiology of infertility.PMID:37643634 | DOI:10.1071/RD22246

Source: Reproduction, Fertility, and Development - August 29, 2023 Category: Reproduction Medicine Authors: Aswathi Cheredath Shubhashree Uppangala Ameya Jijo R Vani Lakshmi G A Nagana Gowda Guruprasad Kalthur Satish Kumar Adiga Source Type: research