Mirtazapin als Add-on zu herk ömmlichen Antidepressiva bei Therapieresistenz ist nicht wirksam.
Mirtazapin als Add-on zu herkömmlichen Antidepressiva bei Therapieresistenz ist nicht wirksam. Praxis (Bern 1994). 2019;108(4):287-288 Authors: Steurer J PMID: 30890088 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 22, 2019 Category: General Medicine Authors: Steurer J Tags: Praxis (Bern 1994) Source Type: research

[CME Sonography 85/Answer: Hypertension and Abnormal Kidney Left].
PMID: 30890089 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 22, 2019 Category: General Medicine Authors: Tuma J Tags: Praxis (Bern 1994) Source Type: research

[IT Outsourcing and Medical Secrecy].
Abstract IT Outsourcing and Medical Secrecy Abstract. When medical practices outsource IT work, the requirements of data protection laws and professional secrecy in particular must be taken into account. In terms of data protection laws, outsourcing to third parties requires, among other things, that an agreement is concluded, and that the outsourcing provider only processes the data in the way that the doctor himself is permitted to do. Furthermore, outsourcing must not be prohibited by a legal or contractual obligation to maintain secrecy, such as medical professional secrecy. Professional secrecy has been widel...
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Widmer M, Egli P Tags: Praxis (Bern 1994) Source Type: research

[Division of Physicians' Day-To-Day Work - Basic Principles of Legal Requirements for Interdisciplinary and Interprofessional Medical Cooperation].
Abstract Division of Physicians' Day-To-Day Work - Basic Principles of Legal Requirements for Interdisciplinary and Interprofessional Medical Cooperation Abstract. Insofar as a personal medical performance is not indicated as a result of an explicit special statutory conditional task or a strictly personal specialist activity is required due to compliance with the boundaries of the specialist area, tasks outside the medical core area may be transferred to appropriately qualified medical or non-medical specialists. Furthermore, the patients shall be informed about the transfer of tasks and such transfer must be avo...
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Olah M Tags: Praxis (Bern 1994) Source Type: research

[CME-Rheumatology 18/Answer: General Symptoms and Pleural Effusion in Rheumatoid Arthritis].
PMID: 30838952 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Gratzl S, Tamborrini G Tags: Praxis (Bern 1994) Source Type: research

[Federal Supreme Court Decisions in Medical Law (2000-2017) - Overview and Selected Case Reports].
UJ Abstract Federal Supreme Court Decisions in Medical Law (2000-2017) - Overview and Selected Case Reports Abstract. Within the framework of an empirical and casuistic analysis of Federal Court decisions in medical law between 2000 and 2017, the goal was to describe tendencies and patterns of Federal Court decisions in medical law. Among other things, our results show that specialists in internal medicine, psychiatry, gynecology, obstetrics and surgery are more frequently involved in federal court proceedings. By contrast, pathologists, forensic specialists or (diagnostic) radiologists are rarely represented. Th...
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Vokinger KN, Mühlematter UJ Tags: Praxis (Bern 1994) Source Type: research

[So That My Will May Be Done - Implementation of the Patient's Will by Means of Advance Care Planning].
r B Abstract So That My Will May Be Done - Implementation of the Patient's Will by Means of Advance Care Planning Abstract. The current developments regarding ACP in Switzerland are an important step towards overcoming the existing deficits and weaknesses of 'traditional' living wills. As global research has shown, the wishes and treatment preferences of patients who, due to their inability to judge, are no longer able to express themselves about medical treatment options, can actually be respected and implemented in this way. PMID: 30838954 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Dörr B Tags: Praxis (Bern 1994) Source Type: research

[CME: Evaluation of Hypokalemia].
Abstract CME: Evaluation of Hypokalemia Abstract. Hypokalemia is a common electrolyte abnormality in clinical practice. While often asymptomatic, it can be associated with severe adverse outcomes. The etiology is often obvious or can be established based on clinical history. In other cases, a systematic approach and knowledge of the physiologic and pathophysiologic key players are necessary. Pathophysiologically, inadequate intake, extra- to intracellular shift and potassium loss (renal, gastrointestinal, sweat) or a combination thereof can contribute to hypokalemia. In this article we discuss the differential dia...
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Diebold M, Kistler AD Tags: Praxis (Bern 1994) Source Type: research

Regulatory Challenges to Swiss Biobanks: A Qualitative Study.
JV PMID: 30838956 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Dörr B, Zeh RM, Rodriguez Torres LM, Stoyanov JV Tags: Praxis (Bern 1994) Source Type: research

[The Role of the Medical Profession in Euthanasia, Particularly in the Prescription of Sodium Pentobarbital].
TX Abstract The Role of the Medical Profession in Euthanasia, Particularly in the Prescription of Sodium Pentobarbital Abstract. The delivery of sodium pentobarbital as part of assisted suicide requires a doctor's prescription. This prescription must meet the legal and professional requirements as well as the corresponding ethical guidelines. Current legal practice restrictively permits suicide assistance in this form, especially in the case of patients who are willing to die and whose death is foreseeable. The new guidelines of the SAMS (2018) extend the possibility to patients who suffer intolerably due to dise...
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Gächter T, Truong TX Tags: Praxis (Bern 1994) Source Type: research

[CME Answers: Depression in Primary Care, Praxis No. 2].
PMID: 30838958 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Checcucci M, Brunner E Tags: Praxis (Bern 1994) Source Type: research

Grenzen ärztlicher Zuständigkeit: Verzahnungen von Medizin und Recht.
Grenzen ärztlicher Zuständigkeit: Verzahnungen von Medizin und Recht. Praxis (Bern 1994). 2019;108(3):173 Authors: Gächter T PMID: 30838959 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Gächter T Tags: Praxis (Bern 1994) Source Type: research

Aspirin ® 100 mg bei über 70-Jährigen ohne Indikation eher schädlich als nützlich.
Aspirin® 100 mg bei über 70-Jährigen ohne Indikation eher schädlich als nützlich. Praxis (Bern 1994). 2019;108(3):225-226 Authors: Steurer J PMID: 30838960 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Steurer J Tags: Praxis (Bern 1994) Source Type: research

[Individualized Medicine, Electronic Patient File and Further Use of Health Data].
Abstract Individualized Medicine, Electronic Patient File and Further Use of Health Data Abstract. The present article is dedicated to the two subject areas 'individualized medicine' and 'electronic patient file'. Both individualised medicine and the electronic patient file generate numerous different health data. The article focuses on the value of health data for human research and discusses the further use of the data according to the Human Research Act. At present, the Human Research Act does not provide for the possibility of making data from the electronic patient file accessible for research. However, effor...
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Baur I Tags: Praxis (Bern 1994) Source Type: research

[CME Sonography 85: Hypertension and Abnormal Kidney Left].
PMID: 30838962 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Tuma J Tags: Praxis (Bern 1994) Source Type: research

Postherpetische Neuralgie im Thoraxbereich: gepulste Radiofrequenztherapie ist wirksam.
PMID: 30838963 [PubMed - in process] (Source: Praxis)
Source: Praxis - March 8, 2019 Category: General Medicine Authors: Steurer J Tags: Praxis (Bern 1994) Source Type: research

[Sleep Disturbances in General Practitioners' Offices: From Screening to Initial Therapy - Update 2019].
Abstract Sleep Disturbances in General Practitioners' Offices: From Screening to Initial Therapy - Update 2019 Abstract. The field of sleep medicine has established internationally as an interdisciplinary specialization. Due to prevailing evidence, sleep disturbances are listed in a separate chapter in the new ICD 11 classification system. With the International Classification of Sleep Disorders (ICSD-3rd version) a standalone classification system exists. In Switzerland, one third of the population suffers from sleep disturbances. Even differential diagnosis is hard to establish. The current article aims at pract...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Acker JG, Cordi MJ Tags: Praxis (Bern 1994) Source Type: research

[Obstructive Sleep Apnea Syndrome].
KE Abstract Obstructive Sleep Apnea Syndrome Abstract. The obstructive sleep apnea syndrome (OSAS) is a disorder of the control of breathing in which repetitive collapse of the upper airway during sleep leads to frequent apneas/hypopneas with cyclic oxygen desaturation and arousals. Sleep is fragmented and unrefreshing. The affected patients suffer from an increased tendency to fall asleep, impaired concentration and a reduced quality of life. The consequences of OSAS also include an increased risk of accidents caused by falling asleep as well as cardiovascular diseases. The diagnosis of OSAS is based on a typica...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Stöwhas AC, Lichtblau M, Bloch KE Tags: Praxis (Bern 1994) Source Type: research

[CME: Depression in Primary Care].
Abstract CME: Depression in Primary Care Abstract. Depressions belong to the most common illnesses at all and to the five most common illnesses in the primary care. The primary care is the first point of contact for depressive patients and therefore has a key role in the early detection and initial treatment of depressive patients. A depressive disorder presents frequently with diffuse, unspecific and mostly somatic complaints. In the primary care only about half of the depressive disorders are detected. An undetected and untreated depression can have fatal consequences for the patients. Once detected, a depressiv...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Checcucci M, Brunner E Tags: Praxis (Bern 1994) Source Type: research

Viel trinken reduziert die Rezidivh äufigkeit akuter Blasenentzündungen.
Viel trinken reduziert die Rezidivhäufigkeit akuter Blasenentzündungen. Praxis (Bern 1994). 2019 Jan;108(2):161-162 Authors: Steurer J PMID: 30722733 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Steurer J Tags: Praxis (Bern 1994) Source Type: research

[Pharmacotherapy of Sleep-Wake Disorders].
Abstract Pharmacotherapy of Sleep-Wake Disorders Abstract. Sleep is a complex behavior, coordinated by many different brain regions and neurotransmitters. These neurochemical systems can be pharmacologically influenced to modulate wakefulness and sleep. Excessive daytime sleepiness (EDS) is often treated with dopaminergic drugs, which in mild cases range from caffeine via (ar)modafinil to amphetamine derivatives. Tricyclic antidepressants and melatonin-based drugs are also used to promote alertness, but to a lesser extent. The drugs used to promote sleep include GABA-ergic drugs such as benzodiazepines and Z-hypno...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Holst SC, Werth E, Landolt HP Tags: Praxis (Bern 1994) Source Type: research

[CME-Rheumatology 18: General Symptoms and Pleural Effusion in Rheumatoid Arthritis].
PMID: 30722735 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Gratzl S, Tamborrini G Tags: Praxis (Bern 1994) Source Type: research

Amitriptylin in niedriger Dosierung zur Therapie von Patienten mit chronischen lumbalen R ückenschmerzen.
Amitriptylin in niedriger Dosierung zur Therapie von Patienten mit chronischen lumbalen Rückenschmerzen. Praxis (Bern 1994). 2019 Jan;108(2):163-164 Authors: Steurer J PMID: 30722736 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Steurer J Tags: Praxis (Bern 1994) Source Type: research

[Sleep Disorders in Old Age].
l D Abstract Sleep Disorders in Old Age Abstract. Sleep disorders increase with age. Older patients rarely complain about sleep disorders, therefore it is important to ask about sleep problems. Insomnias, sleep-disordered breathing and restless legs syndrome tend to increase with older age. It is important to consider that sleep disorders may be the first symptom of a depression, anxiety disorder or neurodegenerative disorders such as dementias. Many factors can influence sleep in old age: it is important to inquire after sleeping habits including naps during the day, medication and comorbidity. Treatment depends ...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Flügel D Tags: Praxis (Bern 1994) Source Type: research

[Sleep-Disordered Breathing in Childhood].
Abstract Sleep-Disordered Breathing in Childhood Abstract. One out of ten healthy children is a habitual snorer, and one fourth of snoring children suffer from obstructive sleep apnea syndrome (OSAS). While OSAS is widely recognized as a relevant social and health problem due to its negative impact on behavior and neurocognitive development, the medical significance of habitual snoring remains debated. Sleep-disordered breathing remains underestimated and underdiagnosed in childhood, in part due to the variability of clinical manifestations. This is particularly true for children with an underlying syndromal morbi...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Trachsel D, Datta AN Tags: Praxis (Bern 1994) Source Type: research

[A Child's Sleep: A Book with Seven Seals? A Guide to Systematic Problem Identification and Solution].
Abstract A Child's Sleep: A Book with Seven Seals? A Guide to Systematic Problem Identification and Solution Abstract. The sleep of a child can be influenced and sometimes disturbed by many, often development-associated, phenomena. This results not only in a burden for the child, but regularly also for the parents, who in their need for help, often seek the advice of the attending physician. The child- and adolescent-specific questionnaire BEARS, which was developed by J. Owens and K. Mindell, allows the first diagnostic steps and classifications based on the most important symptoms such as bedtime problems, exces...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Datta AN, Trachsel D Tags: Praxis (Bern 1994) Source Type: research

Schlafst örungen im Lebenszyklus.
Schlafstörungen im Lebenszyklus. Praxis (Bern 1994). 2019 Jan;108(2):87-88 Authors: Zumsteg U, Suter PM PMID: 30722740 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Zumsteg U, Suter PM Tags: Praxis (Bern 1994) Source Type: research

[CME Answers: 'Dehydration and Artificial Hydration for Terminally Ill Patients', Praxis No. 1].
PMID: 30722741 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Gund SM, Fehr T, Camartin C Tags: Praxis (Bern 1994) Source Type: research

[Thoughts about Light and Sleep].
Abstract Thoughts about Light and Sleep Abstract. Many aspects of health and disease are mainly determined by the constant change between light and darkness during a solar day. The resulting physiological rhythms correspond to the circadian rhythm, which was one of the most central drivers in the evolution of humans. However, over the last 20-30 years, these natural rhythms of the change of light and darkness are being increasingly ignored by modern societies. It is well known that these rhythms are modulators of many physiological pathways and any desynchronization or misalignment will activate different pathophy...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Suter PM Tags: Praxis (Bern 1994) Source Type: research

[Shift Work and Sleep].
Abstract Shift Work and Sleep Abstract. Shift work and night work are necessary in our society today. In Europe, on average about 20 % of the working population work shifts; in Switzerland it is slightly lower at 14.7 %. The proportion of the working population who regularly work night shifts is much lower: 7 % of the working population in Europe and 5 % in Switzerland. The changed daily routine in night work and shift work leads to disturbances in our biological rhythms, which adapt only slowly to the new conditions. This often leads to a lack of sleep, poor sleep quality, reduced recovery and increased strain on...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Hicklin D, Schwander J Tags: Praxis (Bern 1994) Source Type: research

[CME ECG 62/Answer: An Atypical Right Bundle Branch Block?]
PMID: 30722744 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Werner R, Niederseer D, Saguner AM, Brunckhorst CB Tags: Praxis (Bern 1994) Source Type: research

[CME Dermatology 18/Answer: Fatigue, Periungual Ulcer and Group Erosions of the Lower Abdomen].
PMID: 30621531 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Muggli D, Lautenschlager S Tags: Praxis (Bern 1994) Source Type: research

[The 'Dangerous' ECG].
Abstract The 'Dangerous' ECG Abstract. This review aims to draw the attention of physicians confronted with cardiac emergencies to some specific ECG pathomorphologies in acute coronary syndrome and pulmonary embolism, as well as to malignant arrhythmias in hyperkalemia, drug-induced QTc prolongation, WPW, and arrhythmogenic right ventricular cardiomyopathy. If they are not detected the resultant failure to treat or incorrect treatment can have serious consequences for the patient and the doctor (liability consequences). PMID: 30621532 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Flury G Tags: Praxis (Bern 1994) Source Type: research

Meniskusriss: Physiotherapie ist arthroskopischer Meniskektomie nicht unterlegen.
PMID: 30621533 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Steurer J Tags: Praxis (Bern 1994) Source Type: research

[An Unusual Hemisphere Syndrome].
Abstract An Unusual Hemisphere Syndrome Abstract. A patient with known hereditary hemorrhagic telangiectasia presents with transient right arm weakness and dizziness. A transient ischemic attack is diagnosed on clinical and risk factors. In the course of the disease, the patient suffers a convulsive event and fever occurs twice without a clear focus on the infection. The initial skull MRI shows a centroparietal lesion on the left with signs of accompanying edema. Due to this unusual concomitant edema, a neoplastic event must also be considered for differential diagnosis. However, the further examinations show no e...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Barandun S, Wyss A, Stucki A Tags: Praxis (Bern 1994) Source Type: research

[Preterm Birth Screening: What Does Really Make Sense?]
Abstract Preterm Birth Screening: What Does Really Make Sense? Abstract. Spontaneous preterm birth is a syndrome triggered by multiple mechanisms. In view of the pathophysiological heterogeneity of preterm birth, a single biomarker cannot show the required high negative and positive predictive values. From a clinical point of view, anamnesis, sonographic measurement of cervical length, and placental alpha-microglobulin-1 (PAMG-1) testing from cervico-vaginal secretion are established. Further prospective, large-scale longitudinal studies must validate the combined use of new biomarkers. PMID: 30621535 [PubMed...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Amylidi-Mohr S, Mueller M Tags: Praxis (Bern 1994) Source Type: research

Chirurgie bei Patienten mit geminderter Immunlage.
PMID: 30621536 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Goede J Tags: Praxis (Bern 1994) Source Type: research

[Drug-Based Therapy of Varicose Veins from the Perspective of Experimental Models].
Abstract Drug-Based Therapy of Varicose Veins from the Perspective of Experimental Models Abstract. Varicose remodeling of the venous wall primarily occurs in the lower extremities and is often associated with venous insufficiency. Although a large part of the western population shows various degrees of varicosis, little is known about the mechanisms driving their formation. In recent years, experimental animal models have spurred the identificatoin of target molecules and cellular mechanisms that control varicose remodeling processes. Thus, the chronic increase in venous wall tension appears to be a crucial deter...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Arnold C, Korff T Tags: Praxis (Bern 1994) Source Type: research

[Immunosuppression, Surgery, Complication?]
Abstract Immunosuppression, Surgery, Complication? Abstract. Surgical conditions sometimes pose major diagnostic and therapeutic challenges for immunosuppressed patients. Especially in patients suffering from diseases with potential septic emergencies or postoperative complications, the indication for elective surgery should be discussed at an early stage. This is best done across disciplines, involving all experts and the patient. PMID: 30621538 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Christen D Tags: Praxis (Bern 1994) Source Type: research

[CME: Dehydration and Artificial Hydration for Terminally Ill Patients].
Abstract CME: Dehydration and Artificial Hydration for Terminally Ill Patients Abstract. Parenteral hydration in dying patients is a controversial therapy and leads to different attitudes in caregivers as well as in relatives. A reduced liquid intake should be understood as part of the natural dying process. An artificial hydration can lead to adverse effects in some situations, but also to a benefit in others. Nevertheless, there are indications that justify artificial hydration and others that rather forbid it. In case of uncertainty about hydration, there is the option for a limited trial of therapy. Subcutaneo...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Gund SM, Fehr T, Camartin C Tags: Praxis (Bern 1994) Source Type: research

CME-Antworten: «Primärer Hyperparathyreoidismus» aus Praxis Nr. 25.
CME-Antworten: «Primärer Hyperparathyreoidismus» aus Praxis Nr. 25. Praxis (Bern 1994). 2019 Jan;108(1):77 Authors: Egger A, Fischli S PMID: 30621540 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Egger A, Fischli S Tags: Praxis (Bern 1994) Source Type: research

«Praxis 2019»: Ausblick.
«Praxis 2019»: Ausblick. Praxis (Bern 1994). 2019 Jan;108(1):7 Authors: Endemann H, Battegay E PMID: 30621541 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Endemann H, Battegay E Tags: Praxis (Bern 1994) Source Type: research

[CME ECG 62: An Atypical Right Bundle Branch Block?]
PMID: 30621542 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Werner R, Niederseer D, Saguner AM, Brunckhorst CB Tags: Praxis (Bern 1994) Source Type: research

Weiterbildung in Hausarztmedizin: Praxisassistenz und Curriculaweiterbildung (Rotationsstellen) in der Schweiz.
h M PMID: 30621543 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Häuptle C, von Erlach M Tags: Praxis (Bern 1994) Source Type: research

[Sexual Dysfunction in Primary Health Care].
CONCLUSION: Despite an inconspicuous anamnesis regarding risk factors of sexual dysfunction, about a quarter of the sample found evidence of sexual dysfunction. An inconspicuous anamnesis in the areas of alcohol/tobacco consumption and depression does not make a targeted questioning about sexual dysfunction superfluous. Particularly for men, acute psychological stress should be a sufficient reason to address the topic of sexuality and to deepen it if necessary. PMID: 30621544 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Gürtler MA, Brunner P, Dürsteler-MacFarland KM, Wiesbeck GA Tags: Praxis (Bern 1994) Source Type: research

Unkomplizierte Appendizitis: Antibiotika anstatt Operation.
PMID: 30621545 [PubMed - in process] (Source: Praxis)
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Steurer J Tags: Praxis (Bern 1994) Source Type: research

[Genetics of Amyotrophic Lateral Sclerosis].
Abstract Genetics of Amyotrophic Lateral Sclerosis Abstract. In recent years, the knowledge of gene mutation that can lead to amyotrophic lateral sclerosis (ALS), frontotemporal dementia, or a FTD-ALS complex has been drastically improvedwith the help of next-generation sequencing (NGS), so that many new genes and their molecular genetic mechanisms and symptoms of the patients could be described. For example it was found that in the same family with the same gene mutation patients with ALS, FTD or another neurodegenerative disease can be found. The knowledge about the genes does not only contribute to the understa...
Source: Praxis - January 1, 2019 Category: General Medicine Authors: Czell D Tags: Praxis (Bern 1994) Source Type: research

[Odd Aspects of Hemochromatosis, a Widespread Disease].
e B Abstract Odd Aspects of Hemochromatosis, a Widespread Disease Abstract. This case series is written to investigate the odd aspects of hemochromatosis, a frequently encountered disease in our latitudes (and even a widespread disease in Ireland). One patient presented with bilateral digital artery occlusion and another one with bilateral rib fractures. Quite often, hemochromatosis comes with a surprise. PMID: 30537891 [PubMed - in process] (Source: Praxis)
Source: Praxis - December 14, 2018 Category: General Medicine Authors: Jäckel K, Knechtle B Tags: Praxis (Bern 1994) Source Type: research

Diagnostik des Karpaltunnelsyndroms: Wert der Sonografie im Vergleich zur elektrophysiologischen Untersuchung.
n E Abstract Diagnosis of Carpal Tunnel Syndrome: Value of Ultrasound Compared to Nerve Conduction Studies Abstract. Carpal tunnel syndrome is the most common compression syndrome of the peripheral nerves. The patient's history with nocturnal brachialgia, daytime brachialgia, nocturnal paraesthesia and daytime paraesthesia (part of the 6-item CTS symptom scale) and a specific clinical exam take part while making a diagnosis. Additional diagnostics include electrophysiological testings. A high-resolution ultrasound examination for the evaluation of the morphology of the median nerve has gained importance in diagnos...
Source: Praxis - November 15, 2018 Category: General Medicine Authors: Schmid P, Badur N, Kluge S, Vögelin E Tags: Praxis (Bern 1994) Source Type: research

[CME: Thyrotoxicosis and Thyroiditis].
Abstract Hyperthyroidism is caused by an increased synthesis of thyroid hormones or release of preformed thyroid hormones due to destruction of thyroid tissue, or there is an exogenous extrathyroidal source. The term thyroiditis describes a heterogeneous group of disorders, which result in destruction of thyroid tissue and release of preformed thyroid hormones. Although a less common condition, a thyroiditis remains an important differential diagnosis for thyrotoxicosis, and a symptomatic therapy is the cornerstone of treatment. Because of the classical triphasic clinical course a 'wait and see strategy' is reason...
Source: Praxis - November 1, 2018 Category: General Medicine Authors: Slahor L Tags: Praxis (Bern 1994) Source Type: research