PLoS Biology: Archived Table of Contents 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Harnessing online digital data in biodiversity monitoring
by Andrea Soriano-Redondo, Ricardo A. Correia, Vijay Barve, Thomas M. Brooks, Stuart H. M. Butchart, Ivan Jari ć, Ritwik Kulkarni, Richard J. Ladle, Ana Sofia Vaz, Enrico Di Minin
Online digital data from media platforms have the potential to complement biodiversity monitoring efforts. We propose a strategy for integrating these data into current biodiversity datasets in light of the Kunming-Montreal Global Biodiversity Framework.
Online digital data from traditional and social media platforms has the potential to complement biodiversity monitoring efforts. In this Perspective, the authors propose a strategy for integra...
Source: PLoS Biology: Archived Table of Contents - February 15, 2024 Category: Biology Authors: Andrea Soriano-Redondo Source Type: research
Original speech and its echo are segregated and separately processed in the human brain
by Jiaxin Gao, Honghua Chen, Mingxuan Fang, Nai Ding
Speech recognition crucially relies on slow temporal modulations ( (Source: PLoS Biology: Archived Table of Contents)
Source: PLoS Biology: Archived Table of Contents - February 15, 2024 Category: Biology Authors: Jiaxin Gao Source Type: research
Correction: Plasmids manipulate bacterial behaviour through translational regulatory crosstalk
by Catriona M. A. Thompson, James P. J. Hall, Govind Chandra, Carlo Martins, Gerhard Saalbach, Supakan Panturat, Susannah M. Bird, Samuel Ford, Richard H. Little, Ainelen Piazza, Ellie Harrison, Robert W. Jackson, Michael A. Brockhurst, Jacob G. Malone (Source: PLoS Biology: Archived Table of Contents)
Source: PLoS Biology: Archived Table of Contents - February 15, 2024 Category: Biology Authors: Catriona M. A. Thompson Source Type: research
Correction: Nonsense mutation suppression is enhanced by targeting different stages of the protein synthesis process
by Amnon Wittenstein, Michal Caspi, Ido Rippin, Orna Elroy-Stein, Hagit Eldar-Finkelman, Sven Thoms, Rina Rosin-Arbesfeld (Source: PLoS Biology: Archived Table of Contents)
Source: PLoS Biology: Archived Table of Contents - February 14, 2024 Category: Biology Authors: Amnon Wittenstein Source Type: research
The type IV pilus chemoreceptor PilJ controls chemotaxis of one bacterial species towards another
by Kaitlin D. Yarrington, Tyler N. Shendruk, Dominique H. Limoli
Bacteria live in social communities, where the ability to sense and respond to interspecies and environmental signals is critical for survival. We previously showed the pathogenPseudomonas aeruginosa detects secreted peptides from bacterial competitors and navigates through interspecies signal gradients using pilus-based motility. Yet, it was unknown whetherP.aeruginosa utilizes a designated chemosensory system for this behavior. Here, we performed a systematic genetic analysis of a putative pilus chemosensory system, followed by high-speed live-imaging and ...
Source: PLoS Biology: Archived Table of Contents - February 13, 2024 Category: Biology Authors: Kaitlin D. Yarrington Source Type: research
Correction: Data-driven analyses of motor impairments in animal models of neurological disorders
by Hardeep Ryait, Edgar Bermudez-Contreras, Matthew Harvey, Jamshid Faraji, Behroo Mirza Agha, Andrea Gomez-Palacio Schjetnan, Aaron Gruber, Jon Doan, Majid Mohajerani, Gerlinde A. S. Metz, Ian Q. Whishaw, Artur Luczak (Source: PLoS Biology: Archived Table of Contents)
Source: PLoS Biology: Archived Table of Contents - February 8, 2024 Category: Biology Authors: Hardeep Ryait Source Type: research
Dynamics of bacterial recombination in the human gut microbiome
by Zhiru Liu, Benjamin H. Good
Horizontal gene transfer (HGT) is a ubiquitous force in microbial evolution. Previous work has shown that the human gut is a hotspot for gene transfer between species, but the more subtle exchange of variation within species —also known as recombination—remains poorly characterized in this ecosystem. Here, we show that the genetic structure of the human gut microbiome provides an opportunity to measure recent recombination events from sequenced fecal samples, enabling quantitative comparisons across diverse commensa l species that inhabit a common environment. By analyzing recent recombi...
Source: PLoS Biology: Archived Table of Contents - February 8, 2024 Category: Biology Authors: Zhiru Liu Source Type: research
The principle of uncertainty in biology: Will machine learning/artificial intelligence lead to the end of mechanistic studies?
by Victor de Lorenzo
Molecular Biology has long tried to discover mechanisms, considering that unless we understand the principles, we cannot develop applications. Now machine learning and artificial intelligence enable direct leaps to application without understanding the principles. Will this herald a decline in mechanistic studies?
Molecular Biology has long tried to discover mechanisms, considering that unless we understand the principles, we cannot develop applications. Now machine learning and artificial intelligence enable direct leaps to application without understanding the principles. Will this herald a decline...
Source: PLoS Biology: Archived Table of Contents - February 8, 2024 Category: Biology Authors: Victor de Lorenzo Source Type: research
How important is EMT for cancer metastasis?
by Toni Celi à-Terrassa, Yibin Kang
Epithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity initially reported in embryonic development, has been increasingly recognized for its importance in cancer progression and metastasis. Despite tremendous progress being made in the past 2 decades in our understanding of the molecular mechanism and functional importance of EMT in cancer, there are several mysteries around EMT that remain unresolved. In this Unsolved Mystery, we focus on the variety of EMT types in metastasis, cooperative and collective EMT behaviors, spatiotemporal characterizatio...
Source: PLoS Biology: Archived Table of Contents - February 7, 2024 Category: Biology Authors: Toni Celi à-Terrassa Source Type: research
Tracing the evolutionary origins of antiviral immunity
by James B. Eaglesham, Philip J. Kranzusch
Animal and bacterial cells use shared mechanisms to defend against viruses. Analyzing 3 families of immune genes, a new study in PLOS Biology illuminates this evolutionary connection and traces the emergence of antiviral signaling across domains of life.
Animal and bacterial cells use shared mechanisms to defend against viruses. This Primer explores a PLOS Biology study which uses analysis of three families of immune genes to illuminate this evolutionary connection and trace the emergence of antiviral signaling across domains of life. (Source: PLoS Biology: Archived Table of Contents)
Source: PLoS Biology: Archived Table of Contents - February 6, 2024 Category: Biology Authors: James B. Eaglesham Source Type: research
Older adults preserve audiovisual integration through enhanced cortical activations, not by recruiting new regions
by Samuel A. Jones, Uta Noppeney
Effective interactions with the environment rely on the integration of multisensory signals: Our brains must efficiently combine signals that share a common source, and segregate those that do not. Healthy ageing can change or impair this process. This functional magnetic resonance imaging study assessed the neural mechanisms underlying age differences in the integration of auditory and visual spatial cues. Participants were presented with synchronous audiovisual signals at various degrees of spatial disparity and indicated their perceived sound location. Behaviourally, older adults were a...
Source: PLoS Biology: Archived Table of Contents - February 6, 2024 Category: Biology Authors: Samuel A. Jones Source Type: research
Oxidative stress changes interactions between 2 bacterial species from competitive to facilitative
In this study, we show with both experiments and a theoretical analysis that varying the concentration of a single compound, linoleic acid (LA), modifies the interaction between 2 bacterial species,Agrobacterium tumefaciens andComamonas testosteroni, from competitive at a low concentration, to facilitative at higher concentrations where LA becomes toxic for one of the 2 species. We demonstrate that the mechanism behind facilitation is that one species is able to reduce reactive oxygen species (ROS) that are produced spontaneously at higher concentrations of LA, allowing for short-term rescue of the species that is sensitiv...
Source: PLoS Biology: Archived Table of Contents - February 5, 2024 Category: Biology Authors: Rita Di Martino Source Type: research
Relation of connectome topology to brain volume across 103 mammalian species
by Maria Grazia Puxeddu, Joshua Faskowitz, Caio Seguin, Yossi Yovel, Yaniv Assaf, Richard Betzel, Olaf Sporns
The brain connectome is an embedded network of anatomically interconnected brain regions, and the study of its topological organization in mammals has become of paramount importance due to its role in scaffolding brain function and behavior. Unlike many other observable networks, brain connections incur material and energetic cost, and their length and density are volumetrically constrained by the skull. Thus, an open question is how differences in brain volume impact connectome topology. We address this issue usi...
Source: PLoS Biology: Archived Table of Contents - February 5, 2024 Category: Biology Authors: Maria Grazia Puxeddu Source Type: research
Intra-lineage microevolution of < i > Wolbachia < /i > leads to the emergence of new cytoplasmic incompatibility patterns
by Alice Namias, Annais Ngaku, Patrick Makoundou, Sandra Unal, Mathieu Sicard, Myl ène Weill
Mosquitoes of theCulex pipiens complex are worldwide vectors of arbovirus, filarial nematodes, and avian malaria agents. In these hosts, the endosymbiotic bacteriaWolbachia induce cytoplasmic incompatibility (CI), i.e., reduced embryo viability in so-called incompatible crosses.Wolbachia infectingCulex pipiens (wPip) cause CI patterns of unparalleled complexity, associated with the amplification and diversification ofcidA andcidB genes, with up to 6 different gene copies described in a singlewPip genome. InwPip, CI is thought to ...
Source: PLoS Biology: Archived Table of Contents - February 5, 2024 Category: Biology Authors: Alice Namias Source Type: research
Cellular arrangement impacts metabolic activity and antibiotic tolerance in < i > Pseudomonas aeruginosa < /i > biofilms
In this study, we examined the microanatomy of biofilms formed by the pathogenic bacteriumPseudomonas aeruginosa and discovered that clonal cells form striations that are packed lengthwise across most of a mature biofilm ’s depth. We identified mutants, including those defective in pilus function and in O-antigen attachment, that show alterations to this lengthwise packing phenotype. Consistent with the notion that cellular arrangement affects access to resources within the biofilm, we found that while the wild ty pe shows even distribution of tested substrates across depth, the mutants show accumulation of substrates at...
Source: PLoS Biology: Archived Table of Contents - February 1, 2024 Category: Biology Authors: Hannah Dayton Source Type: research
