An updated systematic review of neuroprotective agents in the treatment of spinal cord injury
We examined the effects of 15 substances/drugs: methylprednisolone, tirilazad mesylate, erythropoietin, nimodipine, naloxone, Sygen, Rho protein antagonist, granulocyte colony-stimulating factor, autologous macrophages, autologous bone marrow cells, vitamin D, progesterone, riluzole, minocycline, and blood alcohol concentration. Notable improvements in neurological outcomes were observed with progesterone plus vitamin D and granulocyte colony-stimulating factor. In contrast, results for methylprednisolone, erythropoietin, Sygen, Rho Protein, and Riluzole were inconclusive, primarily due to insufficient sample size or outda...
Source: Neurosurgical Review - March 28, 2024 Category: Neurosurgery Source Type: research
Letter to the editor: permanent deterioration of fine motor skills after the resection of tumors in the supplementary motor area
(Source: Neurosurgical Review)
Source: Neurosurgical Review - March 28, 2024 Category: Neurosurgery Source Type: research
Performance of intraoperative neurocognitive tests during awake surgery for patients with diffuse low-grade glioma
AbstractDespite great advancements and the diffusion of awake surgery for brain tumors, the literature shows that the tests applied during the procedure are heterogeneous and non-standardized. This prospective, observational, descriptive study collected data on intraoperative brain mapping and the performance of multiple neurocognitive tests in 51 awake surgeries for diffuse low-grade glioma. Frequency of use and rate of intraoperative findings of different neurocognitive tests were analyzed. Patients mean age at the time of surgery was 35.1 (20 –57) years. We performed 26 (51.0%) surgeries on the left hemisphere (LH) an...
Source: Neurosurgical Review - March 27, 2024 Category: Neurosurgery Source Type: research
Fostering neurosurgery research in low- and middle-income countries: the role of international collaboration
(Source: Neurosurgical Review)
Source: Neurosurgical Review - March 26, 2024 Category: Neurosurgery Source Type: research
Upfront stereotactic radiosurgery versus adjuvant radiosurgery for parasagittal and parafalcine meningiomas: a systematic review and meta-analysis
AbstractParafalcine and parasagittal (PFPS) are common locations for meningiomas. Surgical resection for these tumors, the first-line treatment, poses challenges due to their proximity to critical structures. This systematic review investigates the use of stereotactic radiosurgery (SRS) as a treatment for PFPS meningiomas, aiming to elucidate its safety and efficacy. The review adhered to PRISMA guidelines. Searches were conducted on MEDLINE, Embase, and Cochrane. Inclusion criteria involved studies on SRS for PFPS meningiomas, reporting procedure outcomes and complications. Tumors were presumed or confirmed to be WHO grad...
Source: Neurosurgical Review - March 22, 2024 Category: Neurosurgery Source Type: research
Crucial trials in neurosurgery: a must-know for every neurosurgeon
(Source: Neurosurgical Review)
Source: Neurosurgical Review - March 21, 2024 Category: Neurosurgery Source Type: research
Revolutionizing brain interventions: the multifaceted potential of histotripsy
In conclusion, histotripsy offers diverse potential in the field of brain interventions, encompassing applications ranging from tumor treatment to the management of intracerebral hemorrhage. While challenges such as accurate monitoring and differentiation of treatme nt effects persist, ongoing research efforts and technological advancements continue to expand the role of histotripsy in both neurology and neurosurgery. (Source: Neurosurgical Review)
Source: Neurosurgical Review - March 21, 2024 Category: Neurosurgery Source Type: research
Is there a truly significant reduction in blood loss comparing robot-assisted versus fluoroscopy-assisted pedicle screw implantation in scoliosis surgery?
(Source: Neurosurgical Review)
Source: Neurosurgical Review - March 21, 2024 Category: Neurosurgery Source Type: research
Efficacy and safety of low profile stents in Y-stent assisted coil embolization of wide-necked bifurcation aneurysms: a systematic review and meta-analysis
AbstractLow-profile stents may provide significant advantages in Y-stent-assisted coiling due to their miniaturized design and capability to be delivered through a 0.0165-inch microcatheter. We aim to investigate the safety and efficacy of using these newer versions of stents in Y-stent-assisted coiling for the treatment of wide-necked bifurcation aneurysms. We conducted a systematic review of the PubMed, Embase, Cochrane Library, and Web of Science databases up to September 2023, following the PRISMA guidelines. Eligible studies included ≥ 5 patients with intracranial wide-necked bifurcation aneurysms treated with ...
Source: Neurosurgical Review - March 20, 2024 Category: Neurosurgery Source Type: research
Impact of biologically effective dose on tremor decrease after stereotactic radiosurgical thalamotomy for essential tremor: a retrospective longitudinal analysis
AbstractThis letter to the editor critiques a recent study evaluating the role of biologically effective dose (BED) in stereotactic radiosurgical thalamotomy for essential tremor (ET). The study, conducted retrospectively on 78 ET patients, demonstrates a significant correlation between BED and tremor improvement post-SRS. Moreover, the study suggests adjusting the prescribed dose rather than changing cobalt-60 sources to maintain treatment efficacy while minimizing toxicity. This suggestion aligns with previous research indicating an annual decrease in BED due to cobalt-60 decay. The letter emphasizes the importance of co...
Source: Neurosurgical Review - March 19, 2024 Category: Neurosurgery Source Type: research
Optimizing surgical approaches for anterior communicating artery aneurysms: Development and internal validation of a novel surgical scoring system
ConclusionOur study introduces a new scoring system for ACoA aneurysms, enhancing the use of 3D CTA in daily practice and providing internal validation for the proposed approach. By evaluating objective criteria, this scoring system helps predict surgical risks, prevent complications, and supports personalized evaluation and selection of the surgical approach based on objective criteria. (Source: Neurosurgical Review)
Source: Neurosurgical Review - March 19, 2024 Category: Neurosurgery Source Type: research
Intraoperative ultrasound for surgical resection of high-grade glioma and glioblastoma: a meta-analysis of 732 patients
ConclusionThe use of iUS in surgical resections for HGG and GBM can improve OS and GTR compared to CNN, but it did not affect PFS. These results suggest that iUS reduces mortality associated with HGG and GBM but not the risk of recurrence. These results can provide valuable cost-effective interventions for neurosurgeons in HGG and GBM surgery. (Source: Neurosurgical Review)
Source: Neurosurgical Review - March 18, 2024 Category: Neurosurgery Source Type: research
Letter to the editor: “Management of cerebrospinal‑fluid‑related intracranial abnormalities in frontoethmoidal encephalocele using “Shunt algorithm for frontoethmoidal encephalocele” (SAFE), a retrospective cohort study of published cases”
AbstractThis critique evaluates a recent study on the management of cerebrospinal fluid-related intracranial abnormalities in frontoethmoidal encephalocele, as explored in a retrospective cohort study titled “Shunt Algorithm for Frontoethmoidal Encephalocele (SAFE): A Retrospective Cohort Study of Published Cases.” focusing on their strengths, weaknesses, and suggestions for future research. This highlights the positive impacts of the SAFE algorithm in standardizing treatment protocols, improving pa tient outcomes, and enhancing our understanding of the condition through collaborative data analysis. However, it also ad...
Source: Neurosurgical Review - March 18, 2024 Category: Neurosurgery Source Type: research
Single-cell transcriptome analysis upon ECM-remodeling meningioma cells
This study provides novel insights int o the malignancy of meningiomas. (Source: Neurosurgical Review)
Source: Neurosurgical Review - March 16, 2024 Category: Neurosurgery Source Type: research
Endoscopic resection of third ventricle colloid cysts using an ultrasonic aspirator
We present a series of 11 patients with colloid cysts of the third ventricle. The mean age was 44 years (27–69). All had biventricular hydrocephalus, with a mean cyst diameter of 15 mm (9–20). The lateral ventricle was accessed using the transforaminal approach in seven patients and the transchoroidal approach in three patients. All patients underwent septostomy. The mean endoscopy time was 40 m in (29–68). Complete resection was possible in 10 patients. Median follow-up was 16 months (1–65) with 100% clinical improvement. At the end of follow-up, no patient had recurrence of the lesion. Based on our experience...
Source: Neurosurgical Review - March 16, 2024 Category: Neurosurgery Source Type: research
