Clinical Features and Outcomes of Streptococcus pneumoniae Meningitis in Children: A Retrospective Analysis of 26 Cases in China
Conclusion Pneumococcal meningitis is associated with a poor prognosis in many children. Poor prognosis might be related to early ineffective antibiotic therapy, a combination of systemic failure, neurological problems, and changed inflammatory response. It is important to rapid initiation of appropriate antibiotic therapy if meningitis is suspected. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Neuropediatrics)
Source: Neuropediatrics - October 13, 2021 Category: Neurology Authors: Wang, Wenhui Han, Hong Du, Lijun Li, Zhaoyang Wu, Yunhong Tags: Original Article Source Type: research
Obstructive Hydrocephalous Presenting with Bobble-Head Doll Syndrome
Neuropediatrics DOI: 10.1055/s-0041-1733775 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 26, 2021 Category: Neurology Authors: Franco, Igor de Assis Vale, Thiago Cardoso Freitas, Leonardo Furtado Barbosa, Andr é Vinícius Soares Arag ão, Marcelo de Melo Rodrigues, Marcelo Masruha Tags: Videos and Images in Neuropediatrics Source Type: research
Ketogenic Diet for KARS-Related Mitochondrial Dysfunction and Progressive Leukodystrophy
We present a 5-year-old male patient with an asymmetrical leukodystrophy who showed overt evidence of mitochondrial dysfunction, including elevation of lactate on brain MR spectroscopy and low oxygen consumption rate in fibroblasts. We diagnosed this patient's condition as KARS-related leukodystrophy with cerebral calcification, congenital deafness, and evidence of mitochondrial dysfunction. We employed a ketogenic diet as well as multiple vitamin supplementation with the intention to alleviate mitochondrial dysfunction. The patient showed alleviation of his psychomotor regression and even partial restoration of his abilit...
Source: Neuropediatrics - August 26, 2021 Category: Neurology Authors: Murofushi, Yuka Hayakawa, Itaru Abe, Yuichi Ohto, Tatsuyuki Murayama, Kei Suzuki, Hisato Takenouchi, Toshiki Kosaki, Kenjiro Kubota, Masaya Tags: Short Communication Source Type: research
PPP2R5D-Related Neurodevelopmental Disorder or Developmental and Epileptic Encephalopathy?: A Novel Phenotypic Description and Review of Published Cases
Conclusion PPP2R5D gene variations should be suspected in children with developmental delay, autistic features, macrocephaly with or without epilepsy in the absence of any clear etiology. Dysmorphic features might provide a diagnostic clue. DEE phenotype may also be the presenting feature and might be an underreported entity. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 26, 2021 Category: Neurology Authors: Madaan, Priyanka Kaur, Amrit Saini, Lokesh Paria, Pradip Vyas, Sameer Sharma, Amit R. Sahu, Jitendra K. Tags: Original Article Source Type: research
Principles and Practice of Child Neurology in Infancy
Neuropediatrics DOI: 10.1055/s-0041-1732366 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 26, 2021 Category: Neurology Authors: Maier, Oliver Tags: Book Review Source Type: research
School-Age Outcome of Fetuses with Isolated Complete Septum Pellucidum Agenesis at Prenatal Magnetic Resonance Imaging
Conclusion Our report may provide information of practical value about the school-age outcome of fetuses detected by prenatal MR imaging to carry isolated complete SPA. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 17, 2021 Category: Neurology Authors: Righini, Andrea Izzo, Giana Doneda, Chiara Scelsa, Barbara Parazzini, Cecilia Tags: Original Article Source Type: research
Extremely Preterm Birth and Its Consequences —The ELGAN Study
Neuropediatrics DOI: 10.1055/s-0041-1732326 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 30, 2021 Category: Neurology Authors: Natalucci, Giancarlo Tags: Book Review Source Type: research
Longitudinally Extensive Transverse Myelitis (LETM) and Myopericarditis in a 7-Month-Old Child with SARs-CoV-2 Infection
Conclusion To the evolving literature of neurological complications of SARs-CoV-2 infection, we add the youngest patient described to date with isolated LETM and concomitant cardiac involvement. Our case suggests that clinicians should be aware of this association, although difficult to recognize in infants. Practitioners are encouraged to consider aggressive first-line immunotherapies with the final aim to prevent permanent disability. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 29, 2021 Category: Neurology Authors: Brisca, Giacomo Sotgiu, Stefano Pirlo, Daniela Tubino, Barbara Siri, Laura Chianucci, Benedetta Carta, Alessandra Rossi, Andrea Mallamaci, Marisa Cataldi, Matteo Mancardi, Maria Margherita Tags: Short Communication Source Type: research
Yield of Brain Magnetic Resonance Imaging in Epilepsy Diagnosis from 1998 to 2020: A Large Retrospective Cohort Study
Conclusion Brain MRI is an important tool in epilepsy diagnosis, mainly in focal seizures and infantile spasms. A repeat MRI is mandatory in intractable focal cases to improve the yield of this test. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 29, 2021 Category: Neurology Authors: Stern, Tomer Kornreich, Liora Goldberg, Hadassa Tags: Original Article Source Type: research
Neurodevelopmental Profile in Children Affected by Ocular Albinism
Conclusion Children with OA may share, in addition to a variable combination of ocular signs and symptoms, a neurodevelopment impairment regarding mostly the cognitive, communicative, and social area, especially those with GPR143 mutation. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 29, 2021 Category: Neurology Authors: Galli, Jessica Loi, Erika Morandi, Alessandra Scaglioni, Vera Rossi, Andrea Molinaro, Anna Pasini, Nadia Semeraro, Francesco Ruberto, Giulio Fazzi, Elisa Tags: Original Article Source Type: research
Clinical and Neuroimaging Features of Peroxisomal Disorders
Neuropediatrics DOI: 10.1055/s-0041-1732312 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 23, 2021 Category: Neurology Authors: Herman, Isabella Calame, Daniel G. Tags: Videos and Images in Neuropediatrics Source Type: research
Characteristics of Pediatric Stroke and Association of Delayed Diagnosis with Mortality in a Mexican Tertiary Care Hospital
Conclusions Pediatric stroke is a rare disease; however, its incidence shows a continuous increase. More awareness toward pediatric stroke is needed. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 14, 2021 Category: Neurology Authors: Garza-Alatorre, Gerardo Carrion-Garcia, Ana Luisa Falcon-Delgado, Alfredo Garza-Davila, Elda Carolina Martinez-Ponce de Leon, Angel R Botello-Hernandez, Edgar Tags: Short Communication Source Type: research
Widening the MRI Findings of PLA2G6-Associated Neurodegeneration
Neuropediatrics DOI: 10.1055/s-0041-1731804 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 13, 2021 Category: Neurology Authors: Vithayathil, Joseph Adang, Laura Alves, C ésar A. P. F. Tags: Videos and Images in Neuropediatrics Source Type: research
Spasmodic Abdominal Pain and Other Gastrointestinal Symptoms in Pontocerebellar Hypoplasia Type 2
Conclusion GI symptoms are common in PCH2. We draw attention to episodes of spasmodic abdominal pain seriously, aggravating the condition of the patients, especially their movement disorder, and discuss the role of IAP. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 12, 2021 Category: Neurology Authors: Janzarik, Wibke G. Kr ägeloh-Mann, Ingeborg Langer, Thorsten van Buiren, Miriam Schaefer, Hans E. Gerner, Patrick Tags: Short Communication Source Type: research
Childhood Stroke: Long-Term Outcomes and Health-Related Quality of Life with a Special Focus on the Development of Epilepsy
Conclusion One important finding in our study is that in the long-term course 39% of patients developed epilepsy after a childhood stroke. It occurred as late as 13 years after the acute episode and affected the QoL especially in cognitively less handicapped patients. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 12, 2021 Category: Neurology Authors: von St ülpnagel, C. Kutschker, Sebastian Sperl, Wolfgang Berweck, Steffen Staudt, Martin Berndt, Markus Kluger, G. Tags: Original Article Source Type: research
