Reflex and Spontaneous Movements in Pediatric Patients with Brain Death
Conclusion It is essential for physicians who perform pediatric brain death examinations to recognize the frequency and characteristics of reflex and spontaneous movements, and this article may help in the accurate and prompt diagnosis of brain death. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 28, 2022 Category: Neurology Authors: Kim, Juhyeon Kwon, Oh-Young Kim, Do-Hyung Yang, Tae-Won Kim, Minhwa Lee, Jeongrim Cho, Wonhyun Yeom, Jung Sook Kim, Young-Soo Tags: Original Article Source Type: research
Benign Acute Childhood Myositis: Our Experience on Clinical Evaluation
Conclusion BACM shows to have in most of the cases a favorable evolution, a spontaneous remission of symptoms, and a good prognosis. However, the disorder generates parental distress for the acute presentation and the striking muscle dysfunction. It is worthy a rapid and early diagnosis to avoid unnecessary diagnostic investigations and a careful follow-up necessary to exclude persistence of symptoms or creatine kinase elevation. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 28, 2022 Category: Neurology Authors: D'Amico, Silvia Gangi, Gloria Barbagallo, Massimo Palermo, Toni Finocchiaro, Maria Carla Distefano, Antonella Falsaperla, Raffaele Marino, Silvia Greco, Filippo Smilari, Pierluigi Pavone, Piero Tags: Original Article Source Type: research
Factors Associated with Nontraumatic Spontaneous Subdural Hematomas in Pediatric Patients
Conclusion This study suggests that, in pediatric patients with subdural hematoma with an amount of bleeding requiring surgical management, any underlying comorbidities should be investigated regardless of the presence of a history of trauma. While investigating systemic diseases, special attention should be paid to the presence of arachnoid cysts or disruption in cerebrospinal fluid dynamics along with a history of hematologic diseases. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 28, 2022 Category: Neurology Authors: Ayd ın, Serdar Onur Etli, Mustafa Umut K öylü, Reha Can Varol, Ey üp Yalt ırık, Cumhur Kaan Ramazano ğlu, Ali Fatih Tags: Original Article Source Type: research
No Differences in Cerebral Immunohistochemical Markers following Remote Ischemic Postconditioning in Newborn Piglets with Hypoxia –Ischemia
Conclusion RIPC did not influence brain expression of markers related to edema, apoptosis, or angiogenesis in newborn piglets at 72 hours after HI. These results support previous findings of limited neuroprotective effect by this RIPC protocol. Our results may have been affected by the time of assessment, use of fentanyl as anesthetic, or limitations related to our immunohistochemical methods. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 28, 2022 Category: Neurology Authors: Andersen, Hannah B. Andersen, Mads Bennedsgaard, Kristine Kerrn-Jespersen, Sigrid Kyng, Kasper J. Holm, Ida E. Henriksen, Tine B. Tags: Original Article Source Type: research
The Impact of “Fear of Falling” on Physical Performance, Balance, and Ambulation in Duchenne Muscular Dystrophy
Conclusion Ambulatory children with better performance scores had lower levels of FOF despite their history of serious falls and injuries. FOF tends to increase as the symptoms of the disease progresses. Investigating the history of falls and FOF from the earliest period will guide to take precautions and make necessary interventions on time in treatment programs. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 28, 2022 Category: Neurology Authors: Alemdaro ğlu-Gürbüz, İpek İpek, Canan Bulut, Numan Karaduman, Ay şe Y ılmaz, Öznur Tags: Original Article Source Type: research
Developmental Regression, Hypertension, and Pink Extremities in Childhood Mercury Poisoning
Neuropediatrics DOI: 10.1055/a-1788-7340 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - August 28, 2022 Category: Neurology Authors: Ursitti, Fabiana Marano, Marco Locatelli, Carlo A. Ronchi, Anna Valeriani, Massimiliano Vigevano, Federico Fusco, Lucia Tags: Letter to the Editor Source Type: research
Mechanical thrombectomy for acute stroke in a two-month-old patient and review of the literature in infancy
CONCLUSION: MT seems effective and safe in infants similarly to other pediatric ages. In children under two years of age, the presence of comorbidities requiring MCS devices is the main factor underlying poor prognosis. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract (Source: Neuropediatrics)
Source: Neuropediatrics - August 18, 2022 Category: Neurology Authors: Rodr íguez-López, Alberto Gimeno, Isabel Vila, Sara Seoane, Andrea Ballenilla, Federico Ramos, Ana Hilario, Amaya N úñez Enamorado, Noemí Camacho-Salas, Ana Sim ón de las Heras, Rogelio Tags: Short Communications Source Type: research
Mechanical Thrombectomy for Acute Stroke in a 2-Month-Old Patient and Review of the Literature in Infancy
Neuropediatrics DOI: 10.1055/s-0042-1750735Mechanical thrombectomy (MT) in pediatric stroke is supported by studies in adults, but there is controversy regarding younger patients. The main growth of intracranial vessels occurs up to 2 years when there can be more difficulties in MT.Description of the MT performed in a 2-month-old patient—the youngest infant published to date. We also review the literature on MT for stroke in infants.A 2-month-old patient presented with an awakening stroke secondary to an occlusion of the M1 segment of the left middle cerebral artery. A successful MT was performed with an aspiration devic...
Source: Neuropediatrics - July 24, 2022 Category: Neurology Authors: Rodr íguez-López, Alberto Gimeno, Isabel Vila, Sara Seoane, Andrea Ballenilla, Federico Ramos, Ana Hilario, Amaya N úñez, Noemí Camacho, Ana Sim ón, Rogelio Tags: Short Communication Source Type: research
The Effect of Nusinersen Therapy on Laboratory Parameters of Patients with Spinal Muscular Atrophy
Conclusion Our results support the safety and efficacy of nusinersen. However, changes in Cr levels according to the clinical type and treatment suggested that serum Cr could be a candidate marker for treatment follow-up. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 24, 2022 Category: Neurology Authors: Sar ıkaya Uzan, Gamze Paket çi, Cem G ünay, Çağatay Edem, P ınar Özsoy, Özlem H ız Kurul, Semra Yi ş, Uluç Tags: Original Article Source Type: research
Seroprevalence of MOG and AQP4 Antibodies and Outcomes in an Indian Cohort of Pediatric Acquired Demyelinating Syndromes
This study aimed to determine the seropositivity of myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) and aquaporin-4 antibodies (AQP4-Ab) and outcomes in children with acquired demyelinating syndromes (ADSs). Children (6 months–15 years) with suspected ADS were enrolled and tested for MOG-Ab and AQP4-Ab prospectively over 18 months at a tertiary care hospital in North India. Children with proven nonimmune-mediated neurological disorders were enrolled as controls. Of 79 children with suspected ADS, 66 were enrolled. Among the enrolled children with ADS, acute demyelinating encephalomyelitis (ADEM) (25) was the most...
Source: Neuropediatrics - July 24, 2022 Category: Neurology Authors: Sankhyan, Naveen Rawat, Amit Vyas, Sameer Sahu, Jitendra Kumar Bhagwat, Chandana Madaan, Priyanka Saini, Lokesh Saini, Arushi Gahlot Suthar, Renu Sukhija, Jaspreet Jayashree, Murlidharan Tags: Original Article Source Type: research
Reflex and Spontaneous Movements in Pediatric Patients with Brain Death
Conclusion It is essential for physicians who perform pediatric brain death examinations to recognize the frequency and characteristics of reflex and spontaneous movements, and this article may help in the accurate and prompt diagnosis of brain death. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 24, 2022 Category: Neurology Authors: Kim, Juhyeon Kwon, Oh-Young Kim, Do-Hyung Yang, Tae-Won Kim, Minhwa Lee, Jeongrim Cho, Wonhyun Yeom, Jung Sook Kim, Young-Soo Tags: Original Article Source Type: research
ASXL3 De Novo Variant-Related Neurodevelopmental Disorder Presenting as Dystonic Cerebral Palsy
We report, here, a female individual with a de novo pathogenic c.1210C > T, p.Gln404* nonsense variant in ASXL3, identified within the frame of an ongoing research project applying trio whole-exome sequencing to the diagnosis of dystonic cerebral palsy. The patient presented with a mixture of infantile-onset limb/trunk dystonic postures and secondarily evolving distal spastic contractures, in addition to more typical features of ASXL3-related diseases such as severe feeding issues, intellectual disability, speech impairment, and facial dysmorphic abnormalities. Our case study confirms a role for ASXL3 pathogenic var...
Source: Neuropediatrics - July 21, 2022 Category: Neurology Authors: Švantnerová, Jana Min ár, Michal Radov á, Silvia Koln íková, Miriam Vlkovi č, Peter Zech, Michael Tags: Short Communication Source Type: research
Expanding the Landscape of Spinocerebellar Ataxia Type 5
This study aims to describe clinical, radiological, and genetic data of a child presenting with SCA5, caused by a heterozygous likely pathogenic missense variant in SPTBN2 (NM_006946.3: c.1052G > C, p.Arg351Pro). According to databases and a review of the literature, this is one of few cases of SCA5 from Latin America. Expanding the landscape of SCA5 is relevant to the differential diagnosis of ataxic cerebral palsy and the autosomal recessive cerebellar ataxias. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text ...
Source: Neuropediatrics - July 21, 2022 Category: Neurology Authors: Benevides, Maria Luiza Fran ça Jr, Marcondes Tags: Short Communication Source Type: research
Reply to "Comment: Another Piece of the Puzzle of Anomalous Connectivity in Joubert's Syndrome"
Neuropediatrics DOI: 10.1055/s-0042-1748908 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - July 21, 2022 Category: Neurology Authors: Meoded, Avner Kukreja, Marcia Orman, Gunes Boltshauser, Eugen Huisman, Thierry A G M Tags: Reply to Letter to the Editor Source Type: research
Is Botox Right for Me: When to Assess the Efficacy of the Botox Injection for Chronic Migraine in Pediatric Population
Neuropediatrics DOI: 10.1055/a-1832-9168Botulinum toxin type A (BoNT-A) has shown to be a safe and effective treatment for children with chronic migraines. Our study was to assess the efficacy of the Onabotulinum toxin type A at different intervals after initiation of therapy. We conducted a retrospective and prospective analysis of 34 patients at a children's hospital where children received four rounds of the BoNT-A therapy for the treatment of chronic migraine. Among the 34 patients, 25 patients (age range: 13–21 years), who responded to the BoNT-A therapy, were included in the analysis. Patients received standard 31 ...
Source: Neuropediatrics - July 21, 2022 Category: Neurology Authors: Goenka, Ajay Yu, Sarah G. George, Monica C. Chikkannaiah, Mahesh MacDonald, Sarah Stolfi, Adrienne Kumar, Gogi Tags: Original Article Source Type: research
