Statistical Analysis of the Factors that Affect Postoperative Length of Hospital Stay after Unruptured Intracranial Aneurysm Treatment in Japan: A 20-year Nationwide Multicenter Study
In this study, we aim to clarify the factors that affect the LOS of patients treated for UIAs using the Inpatient Clinico-Occupational Database of the Rosai Hospital Group (ICOD-R). This was a nationwide-multicenter study based on ICOD-R data from 2000 to 2019. Patients diagnosed with UIAs who were treated with clipping or coiling were included in the study. Multivariate analysis was performed to identify the factors affecting LOS. LOS was also compared between groups classified by surgical procedure or treatment period. We identified 3294 patients on the database who underwent clipping or coiling of UIAs during the study ...
Source: Neurologia Medico-Chirurgica - February 14, 2024 Category: Neurosurgery Authors: Yuhei Hoshikuma Takeshi Shimizu Shingo Toyota Tomoaki Murakami Takamune Achiha Motohide Takahara Kazuhiro Touhara Tatsuya Hagioka Maki Kobayashi Haruhiko Kishima Source Type: research
Factors Associated with Early and Late Seizure Related to Aneurysmal Subarachnoid Hemorrhage
We examined factors associated with aSAH-related early and late seizures. Among 297 patients who had aSAH and underwent direct or endovascular surgery, 25 had early seizures and 20 had late seizures. Patients who did not experience any seizures in at least 2-years of follow-up (n = 81) were used as the control group. Early seizures were associated with older age and acute severe nonneurological infection, whereas late seizures were associated with intraparenchymal lesion volume >10 mL and shunt placement. In patients with late seizures, consistency was frequently observed between electroencephalogram and the presence of...
Source: Neurologia Medico-Chirurgica - January 31, 2024 Category: Neurosurgery Authors: Shota Nakashima Hiroki Nishibayashi Rie Yako Masamichi Ishii Naotsugu Toki Masaki Tomobuchi Toshihito Nakai Hiromi Yamoto Yoko Nakanishi Naoyuki Nakao Source Type: research
The Usefulness of Surgical Titanium Microclips for Mucosal Repair in the Frontal Sinus Using ORBEYE: A Technical Note
We report a new technique for mucosal repair in the frontal sinus using surgical titanium microclips. Six consecutive patients who underwent bifrontal craniotomy with frontal sinus exposure and mucosal injury underwent mucosal repair using surgical titanium microclips between April 2019 and August 2022. In all cases, the frontal sinus mucosa was peeled from the inner walls of the frontal sinus to ensure sufficient mucosal margin for clipping using ORBEYE. The repair was accomplished with the microclips in all cases. We also sealed the mucosal wound using fibrin glue and sufficiently filled the frontal sinus with bone debri...
Source: Neurologia Medico-Chirurgica - January 31, 2024 Category: Neurosurgery Authors: Motohide Takahara Tomoaki Murakami Shingo Toyota Shuki Okuhara Kazuhiro Touhara Yuhei Hoshikuma Shuhei Yamada Takamune Achiha Maki Kobayashi Haruhiko Kishima Source Type: research
Long-term Outcomes of Combined Revascularization Surgery for Moyamoya Disease in the Elderly: A Single Institute Experience
Neurol Med Chir (Tokyo). 2024 Jan 24. doi: 10.2176/jns-nmc.2023-0219. Online ahead of print.ABSTRACTThe opportunity to treat older patients with Moyamoya disease (MMD) is increasing. However, the surgical outcomes after combined direct and indirect revascularization for elderly patients with MMD are not fully understood, especially for those ≥60 years old. This retrospective study examined 232 consecutive hemispheres of 165 adults with MMD who underwent combined revascularization. Clinical features and surgical outcomes were compared between the elderly (≥60 years) and nonelderly group (<60 years). Thirteen (5.6%, 6...
Source: Neurologia Medico-Chirurgica - January 24, 2024 Category: Neurosurgery Authors: Kota Kurisu Masaki Ito Haruto Uchino Taku Sugiyama Miki Fujimura Source Type: research
Is Phantom Limb Awareness Necessary for the Treatment of Phantom Limb Pain?
Neurol Med Chir (Tokyo). 2024 Jan 24. doi: 10.2176/jns-nmc.2023-0206. Online ahead of print.ABSTRACTPhantom limb pain is attributed to abnormal sensorimotor cortical representations. Various feedback treatments have been applied to induce the reorganization of the sensorimotor cortical representations to reduce pain. We developed a training protocol using a brain-computer interface (BCI) to induce plastic changes in the sensorimotor cortical representation of phantom hand movements and demonstrated that BCI training effectively reduces phantom limb pain. By comparing the induced cortical representation and pain, the mechan...
Source: Neurologia Medico-Chirurgica - January 24, 2024 Category: Neurosurgery Authors: Huixiang Yang Takufumi Yanagisawa Source Type: research
Characteristics of MicroRNA Expression Depending on the Presence or Absence of Meningioma in Patients with Neurofibromatosis Type 2: A Secondary Analysis
In conclusion, we identified different circulating miRNA expression characteristics depending on the presence or absence of meningioma in patients with NF2.PMID:38267057 | DOI:10.2176/jns-nmc.2023-0200 (Source: Neurologia Medico-Chirurgica)
Source: Neurologia Medico-Chirurgica - January 24, 2024 Category: Neurosurgery Authors: Takeshi Imura Takafumi Mitsuhara Nobutaka Horie Source Type: research
Guidelines for Awake Surgery
Neurol Med Chir (Tokyo). 2024;64(1):1-27. doi: 10.2176/jns-nmc.2023-0111.NO ABSTRACTPMID:38220155 | PMC:PMC10835579 | DOI:10.2176/jns-nmc.2023-0111 (Source: Neurologia Medico-Chirurgica)
Source: Neurologia Medico-Chirurgica - January 14, 2024 Category: Neurosurgery Authors: Guidelines Committee of the Japan Awake Surgery Conference Source Type: research
Utilizing Excitatory and Inhibitory Activity Derived from Interictal Intracranial Electroencephalography as Potential Biomarkers for Epileptogenicity
Neurol Med Chir (Tokyo). 2024 Feb 15;64(2):65-70. doi: 10.2176/jns-nmc.2023-0207. Epub 2024 Jan 15.ABSTRACTEpileptogenic zones (EZs), where epileptic seizures cease after resection, are localized by assessing the seizure-onset zone using ictal electroencephalography (EEG). Owing to the difficulty in capturing unpredictable seizures, biomarkers capable of identifying EZs from interictal EEG are anticipated. Recent studies using intracranial EEG have identified several potential candidate biomarkers for epileptogenicity. High-frequency oscillation (HFO) was initially expected to be a robust biomarker of abnormal excitatory a...
Source: Neurologia Medico-Chirurgica - January 14, 2024 Category: Neurosurgery Authors: Keisuke Nagata Naoto Kunii Seijiro Shimada Nobuhito Saito Source Type: research
Direction-selective Resistance to Cerebrospinal Fluid Flow as the Cause of Syringomyelia
Neurol Med Chir (Tokyo). 2024 Feb 15;64(2):93-99. doi: 10.2176/jns-nmc.2023-0149. Epub 2024 Jan 15.ABSTRACTThe pathophysiology of syringomyelia remains poorly understood. Two prevailing challenges stand out: the need for a comprehensive understanding of its diverse types and the yet-to-be-explained mechanism of cerebrospinal fluid (CSF) retention in the syrinx despite its higher pressure than that in the adjacent subarachnoid space. Expanding on our previous proposal that direction-selective resistance to subarachnoid CSF flow drives syringomyelia genesis, this study uses a computer model to explore this mechanism further....
Source: Neurologia Medico-Chirurgica - January 14, 2024 Category: Neurosurgery Authors: Han Soo Chang Source Type: research
Usefulness of Robotic Stereotactic Assistance (ROSA < sup > ® < /sup > ) Device for Stereoelectroencephalography Electrode Implantation: A Systematic Review and Meta-analysis
Neurol Med Chir (Tokyo). 2024 Feb 15;64(2):71-86. doi: 10.2176/jns-nmc.2023-0119. Epub 2024 Jan 15.ABSTRACTThe aim of this study was to systematically review and meta-analyze the efficiency and safety of using the Robotic Stereotactic Assistance (ROSA®) device (Zimmer Biomet; Warsaw, IN, USA) for stereoelectroencephalography (SEEG) electrode implantation in patients with drug-resistant epilepsy. Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a literature search was carried out. Overall, 855 nonduplicate relevant articles were determined, and 15 of them were selected for analysi...
Source: Neurologia Medico-Chirurgica - January 14, 2024 Category: Neurosurgery Authors: Anukoon Kaewborisutsakul Mikhail Chernov Suguru Yokosako Yuichi Kubota Source Type: research
Epidemiological Study of Metastatic Brain Tumors in Miyazaki Prefecture: A Regional 10-year Survey in Southern Japan
This study included 425 new cases of MBTs diagnosed in Miyazaki Prefecture from 2007 to 2016. As per our findings, the most frequent primary tumor in Miyazaki Prefecture was found to be in the lung (49.4%), followed by colon/rectum/anus (9.4%) and breast (8.5%). Among patients with MBTs, 59.1% were males, a number closely similar to that of Japan, as shown in the Japanese Brain Tumor Registry (55.5%). The median age at diagnosis was 68 and 63 years in Miyazaki Prefecture and Japan, respectively. Although more patients were symptomatic in Miyazaki Prefecture than in Japan (88.5% vs. 15.5%), fewer patients opted for surgery ...
Source: Neurologia Medico-Chirurgica - January 10, 2024 Category: Neurosurgery Authors: Go Takeishi Shinji Yamashita Fumitaka Matsumoto Kiyotaka Saito Takashi Watanabe Takumi Yoneyama Takuji Hinoura Hajime Ohta Kiyotaka Yokogami Yoshiki Kuroda Hideo Takeshima Miyazaki Brain Tumor Research Group Source Type: research
Information-guided Surgery Centered on Intraoperative Magnetic Resonance Imaging Guarantees Surgical Safety with Low Mortality
In this study, we aimed to verify the safety of brain surgery using intraoperative magnetic resonance imaging (iMRI), based on surgical experience since 2000. Thus, we retrospectively examined 2,018 surgical procedures that utilized iMRI performed in the operating room at Tokyo Women's Medical University Hospital between March 2000 and October 2019. As per our data, glioma constituted the majority of the cases (1,711 cases, 84.8%), followed by cavernous hemangioma (61 cases, 3.0%), metastatic brain tumor (37 cases, 1.8%), and meningioma (31 cases, 1.5%). In total, 1,704 patients who underwent glioma removal were analyzed f...
Source: Neurologia Medico-Chirurgica - January 10, 2024 Category: Neurosurgery Authors: Shunsuke Tsuzuki Yoshihiro Muragaki Masayuki Nitta Taiichi Saito Takashi Maruyama Shunichi Koriyama Manabu Tamura Takakazu Kawamata Source Type: research
Synergistic Interaction of Thyroid Autoantibodies and Ring Finger Protein 213 Variant in Moyamoya Disease
Neurol Med Chir (Tokyo). 2024 Jan 15;64(1):43-49. doi: 10.2176/jns-nmc.2023-0169. Epub 2023 Dec 6.ABSTRACTRecently, thyroid autoantibodies were found to be associated with moyamoya disease (MMD). The ring finger protein 213 (RNF213) p.R4810K variant represents the most important susceptibility genotype of this disease, but its relationship with thyroid autoantibodies remains to be elucidated. Thus, in this study, we aimed to evaluate the clinical relevance of thyroid autoantibodies in each RNF213 genotype in patients with MMD. Included in this study were patients with MMD without a thyroid disease history and in euthyroid ...
Source: Neurologia Medico-Chirurgica - December 6, 2023 Category: Neurosurgery Authors: Thiparpa Thamamongood Shoko Hara Hiroyuki Akagawa Motoki Inaji Yoji Tanaka Tadashi Nariai Taketoshi Maehara Source Type: research
Synergistic Interaction of Thyroid Autoantibodies and Ring Finger Protein 213 Variant in Moyamoya Disease
Neurol Med Chir (Tokyo). 2023 Dec 6. doi: 10.2176/jns-nmc.2023-0169. Online ahead of print.ABSTRACTRecently, thyroid autoantibodies were found to be associated with moyamoya disease (MMD). The ring finger protein 213 (RNF213) p.R4810K variant represents the most important susceptibility genotype of this disease, but its relationship with thyroid autoantibodies remains to be elucidated. Thus, in this study, we aimed to evaluate the clinical relevance of thyroid autoantibodies in each RNF213 genotype in patients with MMD. Included in this study were patients with MMD without a thyroid disease history and in euthyroid status;...
Source: Neurologia Medico-Chirurgica - December 6, 2023 Category: Neurosurgery Authors: Thiparpa Thamamongood Shoko Hara Hiroyuki Akagawa Motoki Inaji Yoji Tanaka Tadashi Nariai Taketoshi Maehara Source Type: research
