Differentiation between Anterior and Posterior Roots Using Compound Muscle Action Potential in Intradural Extramedullary Spinal Tumor Surgery
This study aims to determine the cutoff values for the compound muscle action potential (CMAP) stimulus in anatomically identified anterior (motor nerve) and posterior roots (sensory nerve) during cervical intradural extramedullary tumor surgery. The connection between CMAP data from nerve roots and postoperative neurological symptoms in thoracolumbar tumors was compared with data from cervical lesions. The participants of the study included 22 patients with intradural extramedullary spinal tumors (116 nerve roots). The lowest stimulation intensity to the nerve root at which muscle contraction occurs was defined as the min...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Naoyuki Harada Yuki Sakaeyama Yutaka Fuchinoue Mitsuyoshi Abe Sayaka Terazono Chie Matsuura Shuhei Kubota Masataka Mikai Nobuo Sugo Kunio Sugiyama Kosuke Kondo Masaaki Nemoto Source Type: research
Platelet-derived Growth Factor Activates Pericytes in the Microvessels of Chronic Subdural Hematoma Outer Membranes
This study examined the pericyte expressions in CSDH outer membranes obtained during trepanation surgery. Eight samples of CSDH outer membranes and 35 samples of CSDH fluid were included. NG2, N-cadherin, VE-cadherin, Tie-2, endothelial nitric oxide synthase (eNOS), platelet-derived growth factor (PDGF) receptor-β (PDGFR-β), a well-known marker of pericytes, phosphorylated PDGFR-β at Tyr751, and β-actin expressions, were examined using western blot analysis. PDGFR-β, N-cadherin, and Tie-2 expression levels were also examined using immunohistochemistry. The concentrations of PDGF-BB in CSDH fluid samples were measured ...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Mao Yokota Koji Osuka Yusuke Ohmichi Mika Ohmichi Chiharu Suzuki Masahiro Aoyama Kenichiro Iwami Satoru Honma Shigeru Miyachi Source Type: research
Differentiation between Anterior and Posterior Roots Using Compound Muscle Action Potential in Intradural Extramedullary Spinal Tumor Surgery
This study aims to determine the cutoff values for the compound muscle action potential (CMAP) stimulus in anatomically identified anterior (motor nerve) and posterior roots (sensory nerve) during cervical intradural extramedullary tumor surgery. The connection between CMAP data from nerve roots and postoperative neurological symptoms in thoracolumbar tumors was compared with data from cervical lesions. The participants of the study included 22 patients with intradural extramedullary spinal tumors (116 nerve roots). The lowest stimulation intensity to the nerve root at which muscle contraction occurs was defined as the min...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Naoyuki Harada Yuki Sakaeyama Yutaka Fuchinoue Mitsuyoshi Abe Sayaka Terazono Chie Matsuura Shuhei Kubota Masataka Mikai Nobuo Sugo Kunio Sugiyama Kosuke Kondo Masaaki Nemoto Source Type: research
Platelet-derived Growth Factor Activates Pericytes in the Microvessels of Chronic Subdural Hematoma Outer Membranes
This study examined the pericyte expressions in CSDH outer membranes obtained during trepanation surgery. Eight samples of CSDH outer membranes and 35 samples of CSDH fluid were included. NG2, N-cadherin, VE-cadherin, Tie-2, endothelial nitric oxide synthase (eNOS), platelet-derived growth factor (PDGF) receptor-β (PDGFR-β), a well-known marker of pericytes, phosphorylated PDGFR-β at Tyr751, and β-actin expressions, were examined using western blot analysis. PDGFR-β, N-cadherin, and Tie-2 expression levels were also examined using immunohistochemistry. The concentrations of PDGF-BB in CSDH fluid samples were measured ...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Mao Yokota Koji Osuka Yusuke Ohmichi Mika Ohmichi Chiharu Suzuki Masahiro Aoyama Kenichiro Iwami Satoru Honma Shigeru Miyachi Source Type: research
Differentiation between Anterior and Posterior Roots Using Compound Muscle Action Potential in Intradural Extramedullary Spinal Tumor Surgery
This study aims to determine the cutoff values for the compound muscle action potential (CMAP) stimulus in anatomically identified anterior (motor nerve) and posterior roots (sensory nerve) during cervical intradural extramedullary tumor surgery. The connection between CMAP data from nerve roots and postoperative neurological symptoms in thoracolumbar tumors was compared with data from cervical lesions. The participants of the study included 22 patients with intradural extramedullary spinal tumors (116 nerve roots). The lowest stimulation intensity to the nerve root at which muscle contraction occurs was defined as the min...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Naoyuki Harada Yuki Sakaeyama Yutaka Fuchinoue Mitsuyoshi Abe Sayaka Terazono Chie Matsuura Shuhei Kubota Masataka Mikai Nobuo Sugo Kunio Sugiyama Kosuke Kondo Masaaki Nemoto Source Type: research
Platelet-derived Growth Factor Activates Pericytes in the Microvessels of Chronic Subdural Hematoma Outer Membranes
This study examined the pericyte expressions in CSDH outer membranes obtained during trepanation surgery. Eight samples of CSDH outer membranes and 35 samples of CSDH fluid were included. NG2, N-cadherin, VE-cadherin, Tie-2, endothelial nitric oxide synthase (eNOS), platelet-derived growth factor (PDGF) receptor-β (PDGFR-β), a well-known marker of pericytes, phosphorylated PDGFR-β at Tyr751, and β-actin expressions, were examined using western blot analysis. PDGFR-β, N-cadherin, and Tie-2 expression levels were also examined using immunohistochemistry. The concentrations of PDGF-BB in CSDH fluid samples were measured ...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Mao Yokota Koji Osuka Yusuke Ohmichi Mika Ohmichi Chiharu Suzuki Masahiro Aoyama Kenichiro Iwami Satoru Honma Shigeru Miyachi Source Type: research
Differentiation between Anterior and Posterior Roots Using Compound Muscle Action Potential in Intradural Extramedullary Spinal Tumor Surgery
This study aims to determine the cutoff values for the compound muscle action potential (CMAP) stimulus in anatomically identified anterior (motor nerve) and posterior roots (sensory nerve) during cervical intradural extramedullary tumor surgery. The connection between CMAP data from nerve roots and postoperative neurological symptoms in thoracolumbar tumors was compared with data from cervical lesions. The participants of the study included 22 patients with intradural extramedullary spinal tumors (116 nerve roots). The lowest stimulation intensity to the nerve root at which muscle contraction occurs was defined as the min...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Naoyuki Harada Yuki Sakaeyama Yutaka Fuchinoue Mitsuyoshi Abe Sayaka Terazono Chie Matsuura Shuhei Kubota Masataka Mikai Nobuo Sugo Kunio Sugiyama Kosuke Kondo Masaaki Nemoto Source Type: research
Platelet-derived Growth Factor Activates Pericytes in the Microvessels of Chronic Subdural Hematoma Outer Membranes
This study examined the pericyte expressions in CSDH outer membranes obtained during trepanation surgery. Eight samples of CSDH outer membranes and 35 samples of CSDH fluid were included. NG2, N-cadherin, VE-cadherin, Tie-2, endothelial nitric oxide synthase (eNOS), platelet-derived growth factor (PDGF) receptor-β (PDGFR-β), a well-known marker of pericytes, phosphorylated PDGFR-β at Tyr751, and β-actin expressions, were examined using western blot analysis. PDGFR-β, N-cadherin, and Tie-2 expression levels were also examined using immunohistochemistry. The concentrations of PDGF-BB in CSDH fluid samples were measured ...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Mao Yokota Koji Osuka Yusuke Ohmichi Mika Ohmichi Chiharu Suzuki Masahiro Aoyama Kenichiro Iwami Satoru Honma Shigeru Miyachi Source Type: research
Differentiation between Anterior and Posterior Roots Using Compound Muscle Action Potential in Intradural Extramedullary Spinal Tumor Surgery
This study aims to determine the cutoff values for the compound muscle action potential (CMAP) stimulus in anatomically identified anterior (motor nerve) and posterior roots (sensory nerve) during cervical intradural extramedullary tumor surgery. The connection between CMAP data from nerve roots and postoperative neurological symptoms in thoracolumbar tumors was compared with data from cervical lesions. The participants of the study included 22 patients with intradural extramedullary spinal tumors (116 nerve roots). The lowest stimulation intensity to the nerve root at which muscle contraction occurs was defined as the min...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Naoyuki Harada Yuki Sakaeyama Yutaka Fuchinoue Mitsuyoshi Abe Sayaka Terazono Chie Matsuura Shuhei Kubota Masataka Mikai Nobuo Sugo Kunio Sugiyama Kosuke Kondo Masaaki Nemoto Source Type: research
Platelet-derived Growth Factor Activates Pericytes in the Microvessels of Chronic Subdural Hematoma Outer Membranes
This study examined the pericyte expressions in CSDH outer membranes obtained during trepanation surgery. Eight samples of CSDH outer membranes and 35 samples of CSDH fluid were included. NG2, N-cadherin, VE-cadherin, Tie-2, endothelial nitric oxide synthase (eNOS), platelet-derived growth factor (PDGF) receptor-β (PDGFR-β), a well-known marker of pericytes, phosphorylated PDGFR-β at Tyr751, and β-actin expressions, were examined using western blot analysis. PDGFR-β, N-cadherin, and Tie-2 expression levels were also examined using immunohistochemistry. The concentrations of PDGF-BB in CSDH fluid samples were measured ...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Mao Yokota Koji Osuka Yusuke Ohmichi Mika Ohmichi Chiharu Suzuki Masahiro Aoyama Kenichiro Iwami Satoru Honma Shigeru Miyachi Source Type: research
Differentiation between Anterior and Posterior Roots Using Compound Muscle Action Potential in Intradural Extramedullary Spinal Tumor Surgery
This study aims to determine the cutoff values for the compound muscle action potential (CMAP) stimulus in anatomically identified anterior (motor nerve) and posterior roots (sensory nerve) during cervical intradural extramedullary tumor surgery. The connection between CMAP data from nerve roots and postoperative neurological symptoms in thoracolumbar tumors was compared with data from cervical lesions. The participants of the study included 22 patients with intradural extramedullary spinal tumors (116 nerve roots). The lowest stimulation intensity to the nerve root at which muscle contraction occurs was defined as the min...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Naoyuki Harada Yuki Sakaeyama Yutaka Fuchinoue Mitsuyoshi Abe Sayaka Terazono Chie Matsuura Shuhei Kubota Masataka Mikai Nobuo Sugo Kunio Sugiyama Kosuke Kondo Masaaki Nemoto Source Type: research
Platelet-derived Growth Factor Activates Pericytes in the Microvessels of Chronic Subdural Hematoma Outer Membranes
This study examined the pericyte expressions in CSDH outer membranes obtained during trepanation surgery. Eight samples of CSDH outer membranes and 35 samples of CSDH fluid were included. NG2, N-cadherin, VE-cadherin, Tie-2, endothelial nitric oxide synthase (eNOS), platelet-derived growth factor (PDGF) receptor-β (PDGFR-β), a well-known marker of pericytes, phosphorylated PDGFR-β at Tyr751, and β-actin expressions, were examined using western blot analysis. PDGFR-β, N-cadherin, and Tie-2 expression levels were also examined using immunohistochemistry. The concentrations of PDGF-BB in CSDH fluid samples were measured ...
Source: Neurologia Medico-Chirurgica - November 29, 2023 Category: Neurosurgery Authors: Mao Yokota Koji Osuka Yusuke Ohmichi Mika Ohmichi Chiharu Suzuki Masahiro Aoyama Kenichiro Iwami Satoru Honma Shigeru Miyachi Source Type: research
Effectiveness of Keyhole Clipping of Unruptured Intracranial Aneurysms Detected by "Brain Dock" in Healthy Japanese Adults
In this study, the differences in neurological and radiological outcomes, as well as cognitive and psychological results, between standard clipping and keyhole clipping for these aneurysms detected via brain docking were evaluated. The study included 131 aneurysms detected via "brain dock." Of these, 65 were treated with keyhole clipping surgery (keyhole clipping group), and 66 were treated with standard clipping surgery (standard clipping group). Evaluations at 3 months included the National Institutes of Health Stroke Scale, modified Rankin Scale, Mini-Mental State Examination, Hasegawa's Dementia Scale-revised, Beck Dep...
Source: Neurologia Medico-Chirurgica - November 8, 2023 Category: Neurosurgery Authors: Toru Yoshiura Satoru Takeuchi Terushige Toyooka Arata Tomiyama Kojiro Wada Yasuaki Nakao Takuji Yamamoto Kentaro Mori Source Type: research
Clinical Significance of Stiffness during Endoscopic Surgery for Intracerebral Hemorrhage: A Retrospective Study
This study explored the association between hematoma stiffness and surgical results of endoscopic hematoma removal for intracerebral hemorrhage. It also aimed to clarify factors associated with hematoma stiffness. We classified intracerebral hematoma as either soft or firm stiffness by retrospectively evaluating operative videos by two neurosurgeons. The interobserver reliability of the classification was assessed by calculating the κ values. We investigated the relationship between hematoma stiffness and surgical results. Favorable hematoma removal (FHR) was defined as a residual hematoma volume of ≤15 mL or removal ra...
Source: Neurologia Medico-Chirurgica - November 8, 2023 Category: Neurosurgery Authors: Kengo Kishida Daisuke Maruyama Saki Kotani Nobukuni Murakami Naoya Hashimoto Source Type: research
Effectiveness of Keyhole Clipping of Unruptured Intracranial Aneurysms Detected by "Brain Dock" in Healthy Japanese Adults
In this study, the differences in neurological and radiological outcomes, as well as cognitive and psychological results, between standard clipping and keyhole clipping for these aneurysms detected via brain docking were evaluated. The study included 131 aneurysms detected via "brain dock." Of these, 65 were treated with keyhole clipping surgery (keyhole clipping group), and 66 were treated with standard clipping surgery (standard clipping group). Evaluations at 3 months included the National Institutes of Health Stroke Scale, modified Rankin Scale, Mini-Mental State Examination, Hasegawa's Dementia Scale-revised, Beck Dep...
Source: Neurologia Medico-Chirurgica - November 8, 2023 Category: Neurosurgery Authors: Toru Yoshiura Satoru Takeuchi Terushige Toyooka Arata Tomiyama Kojiro Wada Yasuaki Nakao Takuji Yamamoto Kentaro Mori Source Type: research
