Adverse renal effects of check-point inhibitors (ICI) in cancer patients: Recommendations of the Onco-nephrology Working Group of the Spanish Society of Nephrology
Nefrologia (Engl Ed). 2023 Sep-Oct;43(5):622-635. doi: 10.1016/j.nefroe.2023.11.001. Epub 2023 Nov 23.ABSTRACTThe most widely used approach in the immunotherapy treatment of cancer is the administration of monoclonal antibodies directed against regulatory molecules of immune control that inhibit the activation of T cells, the so-called check point inhibitors (ICI). ICI nephrotoxicity epidemiology and pathology; its diagnosis with or without kidney biopsy; the type and duration of treatment; the possibility of rechallenging after kidney damage; and its indication in patients with cancer and renal transplantation are certain...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - November 24, 2023 Category: Urology & Nephrology Authors: Fabiola Alonso Ángel L M Martín de Francisco Pilar Au ñón Clara Garc ía-Carro Patricia Garc ía Eduardo Guti érrez Manuel Mc ía Luis F Quintana Borja Quiroga Mar ía José Soler Isidro Torregrosa Onconephrology Group of the Spanish Society of Nephr Source Type: research