Corrigendum: Influences of Orogastric and Nasogastric Tubes on Sucking Pressure during Bottle Feeding in Immature Infants
Kobe J Med Sci. 2023 Sep 25;69(1):S1.ABSTRACTThis corrects the article Kobe J Med Sci. 2023 May 31; 69(1): E25-E32.PMID:37743504 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 24, 2023 Category: General Medicine Authors: Kobe J Med Sci Staff Source Type: research

Current Status and Problems of Newborn Infection Management at a Regional Hospital in Japan
CONCLUSIONS: There were no asymptomatic cases of CRP >2 mg/dL, and no cases of severe sepsis in normal neonatal deliveries. CRP levels were elevated in the AFT group, where culture was positive, but few antibiotics were administered. In the C/S group, antibiotics were administered if respiratory symptoms occurred unless the CRP level was high. Further, all patients in PROM group who received antibiotics had any symptoms, suggesting that routine blood tests may not be necessary.PMID:37661631 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Takeshi Ninchoji Masayo Okuno Tomoko Kihara Shigeki Takekida Jun Maruyama Source Type: research

Transcription Factor JunB Suppresses Hepatitis C Virus Replication
Kobe J Med Sci. 2023 Aug 31;69(3):E86-E95.ABSTRACTWe previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK is known to have numerous target genes, including JunB, a member of activator protein-1 transcription factor family. However, the roles of JunB in the HCV life cycle and HCV-associated pathogenesis remain unclear. To clarify a physiological role of JunB in HCV infe...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Adi Ariffianto Lin Deng Saki Harada Yujiao Liang Chieko Matsui Takayuki Abe Ikuo Shoji Source Type: research

A Case of a Highly Obese Covid-19 Patient with Severe Hypoxemia and Subcutaneous Mediastinal Emphysema Who Was Rescued by Early Introduction of ECMO
Kobe J Med Sci. 2023 Jul 27;69(2):E49-E51.ABSTRACTWe conducted the treatment of a highly obese patient with severe Covid-19 pneumonia who had a history of asthma. When she arrived at the hospital, she was already intubated and had mediastinal emphysema and severe hypoxemia. Because the patient's condition did not improve with mechanical ventilation, we introduced extracorporeal membrane oxygenation (ECMO) immediately after admission. The patient improved with early induction of ECMO and prone positioning. In the management of patients with severe Covid-19 pneumonia, early introduction of ECMO should be considered if oxygen...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Shuhei Takahashi Norihiko Obata Shohei Makino Nana Furushima Taichi Nishimura Satoshi Mizobuchi Source Type: research

Long-term Survival after Treatment of Synchronous Isolated Right External Iliac Lymph Node Metastasis from Ascending Colon Cancer: A Case Report
CONCLUSIONS: Surgical resection and adjuvant chemotherapy may be an effective treatment strategy for synchronous isolated right external iliac lymph node metastases from ascending colon cancer.PMID:37661703 | PMC:PMC10501760 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Yuki Okazoe Satoshi Omiya Takahiro Nakajima Atsuhiko Kishi Masahiro Kido Satoshi Suzuki Tsunenori Fujita Masakazu Ohno Source Type: research

Association between Factor XIII Activity and Clinical Course in Pediatric Patients with Immunoglobulin A Vasculitis
CONCLUSIONS: Factor XIII activity was negatively correlated with the duration of hospitalization, total glucocorticoid dose, and duration of glucocorticoid administration. Factor XIII activity is not only associated with abdominal symptoms but also may be a marker to predict the overall trajectory of acute-phase treatment in pediatric patients with immunoglobulin A vasculitis.PMID:37661704 | PMC:PMC10501757 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Hajime Tanaka Tsukasa Tanaka Oshi Tokuda Hiroko Yamamoto Natsuki Matsunoshita Kanae Takenaka Kenta Tominaga Keiichiro Kawasaki Source Type: research

Gender Disparities in First Authorship at Three Medical Universities in an Area Affected by the Great East Japan Earthquake
Kobe J Med Sci. 2023 Aug 31;69(2):E64-E78.ABSTRACTThe Great East Japan Earthquake that occurred on March 11, 2011, was one of the largest natural disasters in modern times. Publication in medical journals is important aspects of the academic promotion process, and is thus important for all scientists. However, little is known about whether and how substantial natural disasters affect gender disparities in academic productivity in disaster-affected areas. We hypothesized that the Great East Japan Earthquake widened the existing disparities in scientific publishing between male and female researchers. To test this hypothesis...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Yuko Ono Masafumi Saito Kenju Shimomura Kazuaki Shinohara Naoto Yamada Yudai Iwasaki Shigeaki Inoue Joji Kotani Source Type: research

Current Status and Problems of Newborn Infection Management at a Regional Hospital in Japan
CONCLUSIONS: There were no asymptomatic cases of CRP >2 mg/dL, and no cases of severe sepsis in normal neonatal deliveries. CRP levels were elevated in the AFT group, where culture was positive, but few antibiotics were administered. In the C/S group, antibiotics were administered if respiratory symptoms occurred unless the CRP level was high. Further, all patients in PROM group who received antibiotics had any symptoms, suggesting that routine blood tests may not be necessary.PMID:37661631 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Takeshi Ninchoji Masayo Okuno Tomoko Kihara Shigeki Takekida Jun Maruyama Source Type: research

Transcription Factor JunB Suppresses Hepatitis C Virus Replication
Kobe J Med Sci. 2023 Aug 31;69(3):E86-E95.ABSTRACTWe previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK is known to have numerous target genes, including JunB, a member of activator protein-1 transcription factor family. However, the roles of JunB in the HCV life cycle and HCV-associated pathogenesis remain unclear. To clarify a physiological role of JunB in HCV infe...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Adi Ariffianto Lin Deng Saki Harada Yujiao Liang Chieko Matsui Takayuki Abe Ikuo Shoji Source Type: research

A Case of a Highly Obese Covid-19 Patient with Severe Hypoxemia and Subcutaneous Mediastinal Emphysema Who Was Rescued by Early Introduction of ECMO
Kobe J Med Sci. 2023 Jul 27;69(2):E49-E51.ABSTRACTWe conducted the treatment of a highly obese patient with severe Covid-19 pneumonia who had a history of asthma. When she arrived at the hospital, she was already intubated and had mediastinal emphysema and severe hypoxemia. Because the patient's condition did not improve with mechanical ventilation, we introduced extracorporeal membrane oxygenation (ECMO) immediately after admission. The patient improved with early induction of ECMO and prone positioning. In the management of patients with severe Covid-19 pneumonia, early introduction of ECMO should be considered if oxygen...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Shuhei Takahashi Norihiko Obata Shohei Makino Nana Furushima Taichi Nishimura Satoshi Mizobuchi Source Type: research

Long-term Survival after Treatment of Synchronous Isolated Right External Iliac Lymph Node Metastasis from Ascending Colon Cancer: A Case Report
CONCLUSIONS: Surgical resection and adjuvant chemotherapy may be an effective treatment strategy for synchronous isolated right external iliac lymph node metastases from ascending colon cancer.PMID:37661703 | PMC:PMC10501760 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Yuki Okazoe Satoshi Omiya Takahiro Nakajima Atsuhiko Kishi Masahiro Kido Satoshi Suzuki Tsunenori Fujita Masakazu Ohno Source Type: research

Association between Factor XIII Activity and Clinical Course in Pediatric Patients with Immunoglobulin A Vasculitis
CONCLUSIONS: Factor XIII activity was negatively correlated with the duration of hospitalization, total glucocorticoid dose, and duration of glucocorticoid administration. Factor XIII activity is not only associated with abdominal symptoms but also may be a marker to predict the overall trajectory of acute-phase treatment in pediatric patients with immunoglobulin A vasculitis.PMID:37661704 | PMC:PMC10501757 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Hajime Tanaka Tsukasa Tanaka Oshi Tokuda Hiroko Yamamoto Natsuki Matsunoshita Kanae Takenaka Kenta Tominaga Keiichiro Kawasaki Source Type: research

Gender Disparities in First Authorship at Three Medical Universities in an Area Affected by the Great East Japan Earthquake
Kobe J Med Sci. 2023 Aug 31;69(2):E64-E78.ABSTRACTThe Great East Japan Earthquake that occurred on March 11, 2011, was one of the largest natural disasters in modern times. Publication in medical journals is important aspects of the academic promotion process, and is thus important for all scientists. However, little is known about whether and how substantial natural disasters affect gender disparities in academic productivity in disaster-affected areas. We hypothesized that the Great East Japan Earthquake widened the existing disparities in scientific publishing between male and female researchers. To test this hypothesis...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Yuko Ono Masafumi Saito Kenju Shimomura Kazuaki Shinohara Naoto Yamada Yudai Iwasaki Shigeaki Inoue Joji Kotani Source Type: research

Current Status and Problems of Newborn Infection Management at a Regional Hospital in Japan
CONCLUSIONS: There were no asymptomatic cases of CRP >2 mg/dL, and no cases of severe sepsis in normal neonatal deliveries. CRP levels were elevated in the AFT group, where culture was positive, but few antibiotics were administered. In the C/S group, antibiotics were administered if respiratory symptoms occurred unless the CRP level was high. Further, all patients in PROM group who received antibiotics had any symptoms, suggesting that routine blood tests may not be necessary.PMID:37661631 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Takeshi Ninchoji Masayo Okuno Tomoko Kihara Shigeki Takekida Jun Maruyama Source Type: research

Transcription Factor JunB Suppresses Hepatitis C Virus Replication
Kobe J Med Sci. 2023 Aug 31;69(3):E86-E95.ABSTRACTWe previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK is known to have numerous target genes, including JunB, a member of activator protein-1 transcription factor family. However, the roles of JunB in the HCV life cycle and HCV-associated pathogenesis remain unclear. To clarify a physiological role of JunB in HCV infe...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Adi Ariffianto Lin Deng Saki Harada Yujiao Liang Chieko Matsui Takayuki Abe Ikuo Shoji Source Type: research