Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury
In this study, we performed 24 hours intratracheal lipopolysaccharide (LPS) instillation or PBS control as an in vivo ALI model in eight-week-old conditional Edn2 knockout mice (Edn2-iKO), with Edn2-floxed mice as controls. Bronchoalveolar lavage (BAL) fluid and tissue were collected after exsanguination and analyzed for its cellular, molecular, functional, and histological inflammatory phenotypes. We found that Edn2-iKO mice displayed a reduced pro-neutrophilic inflammatory phenotype even after acute LPS treatment, shown by the reduction in the overall protein concentration and neutrophil count in bronchoalveolar lavage f...
Source: Kobe J Med Sci - November 9, 2023 Category: General Medicine Authors: Ahmad Musthafa Gusty Rizky Teguh Ryanto Ratoe Suraya Tatsuya Nagano Yoko Suzuki Tetsuya Hara Ken-Ichi Hirata Noriaki Emoto Source Type: research

Corrigendum: Influences of Orogastric and Nasogastric Tubes on Sucking Pressure during Bottle Feeding in Immature Infants
Kobe J Med Sci. 2023 Sep 25;69(1):S1.ABSTRACTThis corrects the article in Kobe J Med Sci. 2023 May 31; 69(1): E25-E32.PMID:37743504 | PMC:PMC10544758 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - September 24, 2023 Category: General Medicine Authors: Takeshi Komatsu Tatsuya Furukawa Daisuke Kobayashi Sota Iwatani Seiji Yoshimoto Toshihiko Yamashita Yumi Endo Sayaka Katsunuma Masahide Otsu Ken-Ichi Nibu Source Type: research