Screening of heat-killed lactic acid bacteria based on inhibitory activity against oral bacteria and effects of oral administration of heat-killed < em > Ligilactobacillus salivarius < /em > CP3365 on periodontal health in healthy participants: a double-blinded, randomized, placebo-controlled trial
CONCLUSION: HKL CP3365 effectively inhibited oral bacteria growth and was useful for maintaining periodontal health.CLINICAL TRIAL REGISTRATION: [https://www.umin.ac.jp/ctr/index.htm], identifier [UMIN000045656].PMID:37649969 | PMC:PMC10464545 | DOI:10.1080/20002297.2023.2250649 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - August 31, 2023 Category: Microbiology Authors: Shinji Sakata Yukiko Sakamaki Masahiro Yuki Tsutomu Sugaya Tatsuhiko Hirota Source Type: research

Parkinson's disease alters the composition of subgingival microbiome
CONCLUSION: These data demonstrated that Parkinson's disease modifies PD-associated subgingival microbiome.PMID:37649970 | PMC:PMC10464550 | DOI:10.1080/20002297.2023.2250650 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - August 31, 2023 Category: Microbiology Authors: Ekin Yay Melis Yilmaz Hilal Toygar Nur Balci Carla Alvarez Rivas Basak Bolluk Kilic Ali Zirh Bruce Paster Alpdogan Kantarci Source Type: research

Human oral mucosa and oral microbiome interactions following supragingival plaque reconstitution in healthy volunteers: a diet-controlled balanced design proof-of-concept model to investigate oral pathologies
J Oral Microbiol. 2023 Aug 22;15(1):2246279. doi: 10.1080/20002297.2023.2246279. eCollection 2023.ABSTRACTChanges in the oral microbiome may contribute to oral pathologies, especially in patients undergoing cancer therapy. Interactions between oral microbiome and oral mucosa may exacerbate inflammation. We determined whether probiotic-controlled plaque formation could impact proximal oral mucosa gene expression profiles in healthy volunteers. A 3-weeks balanced sample collection design from healthy volunteers (HVs) was implemented. At Week-1 plaques samples and labial mucosa brush biopsies were obtained from HVs in the mor...
Source: Journal of Oral Microbiology - August 25, 2023 Category: Microbiology Authors: Jean-Luc C Mougeot Micaela F Beckman Darla S Morton Jenene Noll Nury M Steuerwald Michael T Brennan Farah Bahrani Mougeot Source Type: research

Trans-cinnamaldehyde loaded chitosan based nanocapsules display antibacterial and antibiofilm effects against cavity-causing < em > Streptococcus mutans < /em >
CONCLUSION: Our results showed that CA@CS NC had antibacterial and antibiofilm effects on S. mutans and inhibit dental caries. Besides, it showed stronger efficacy and less toxicity, and was able to adsorb bacteria releasing CA slowly, providing a new nanomaterial solution for the treatment of dental caries.PMID:37546377 | PMC:PMC10402844 | DOI:10.1080/20002297.2023.2243067 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - August 7, 2023 Category: Microbiology Authors: Ran Mu Hanyi Zhang Zhiyuan Zhang Xinyue Li Jiaxuan Ji Xinyue Wang Yu Gu Xiaofei Qin Source Type: research