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Modulatory effects of Momordica balsamina on Th1/Th2 cytokine profiles in immune-challenged rats
The objective of the present study was to evaluate the immunomodulatory effects of Momordica balsamina (MB) leaves extract in BCG-immunized rats. Thirty rats were randomly divided into five groups (n = 6). MB extract was suspended in 1% carboxymethyl cellulose (CMC). Firstly, animals were challenged ... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - August 20, 2019 Category: Complementary Medicine Source Type: research

Evaluation of cytotoxic activity of triterpenes from Clusia studartiana
Family Clusiaceae is spread throughout tropical as well as temperate zones, presenting many triterpenes, reported as selective antitumoral agents. The aim of this study is to isolate and identify triterpenes from Clusia studartiana C. M. Vieira Gomes da Silva and evaluate their cytotoxicity in melanoma (SKMEL 28) and myeloid leukemia (K562) cell lines. Thus, the hexanic extract was processe... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - August 9, 2019 Category: Complementary Medicine Source Type: research

DPPH radical scavenging activity of extracts from Rhamnus prinoides
Hexane, chloroform, ethyl acetate and methanolic extracts from leaves and stem-bark of Rhamnus prinoides were evaluated for their antioxidant activity by DPPH radical scavenging assay. The leaves extracts showed scavenging activity ranging from 03.330.89 to 55.033.40 g mL-1 while the stem-bark extracts showed relatively strong scavenging activity ranging from 03.651.02 to 59.552.27 g mL-1. T... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - August 9, 2019 Category: Complementary Medicine Source Type: research

Evaluation of antidiabetic activity of the ethanol extract of Momordica charantia L. and the identification of charantine by gas chromatography coupled with Mass spectrometry
The aerial parts of Momordica charantia L. are very often used in traditional Congolese medicine for their multiple virtues. Our study focused on the identification of a well-known antidiabetic molecule: the charantine and also the antidiabetic properties of the ethanol extract of M. charantia L. After being treated with MSTFA (N-Methyl-N-(trimethylsilyl) trifluoroacetamide) and using gas ch... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - July 24, 2019 Category: Complementary Medicine Source Type: research

Phytochemical screening, chromatographic profile and evaluation of antimicrobial and antioxidant activities of three species of the Cyperaceae Juss. Family
Some species of the family Cyperaceae have been studied extensively for presenting bioactive compounds of pharmacological interest. Thus, the present research aimed to investigate the antimicrobial, antioxidant and chemical constituents of Kyllinga odorata Vahl, Oxycaryum cubensis Poepp. Kunth and Rhynchospora nervosa Boeck. Hydroalcoholic extracts (1:1, v:v) of aerial and underground parts... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - July 24, 2019 Category: Complementary Medicine Source Type: research

In vitro antiproliferative potential of Annona senegalensis Pers. and Allophylus africanus P Beauv. plant extracts against selected cancer cell lines
The medicinal plants Annona senegalensis Pers. and Allophylus africanus P Beauv. are used in Tanzania traditional medicine for the treatment of cancer. However, there is no scientific documentation on their therapeutic effectiveness. The present study evaluated antiproliferative potential as an indicator of anticancer activity of A. senegalensis and A. africanus plant species from Tanzania. ... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - July 9, 2019 Category: Complementary Medicine Source Type: research

Evaluation of acute toxicity and sub-acute toxicity of the methanolic extract of Aloe rabaiensis Rendle in BALB/c mice
This study was undertaken to evaluate preclinical acute and sub-acute toxicity of Aloe rabaiensis leaf methanolic extract (ARLME) on BALB/c mice following OECD guidelines 423 and 407, respectively. In an acute oral toxicity test, ARLME was administered to the mice by oral gavage at a single dose of 1000, 2000, 3000, 4000 and 5000 mg/Kg body weight. The mice were observed for toxic signs for ... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - July 9, 2019 Category: Complementary Medicine Source Type: research

Evaluation of active phytochemical constituents linked to the analgesic and anti-inflammatory property of Cassia singueana Del. root bark
This study aimed to investigate the phytochemical constituents of the plants root bark linked to the therapeutics claims of its analgesic and anti-inflammatory activities. The plant material was obtained and identified, and its phytochemical fingerprint profile was established using GC-MS techniq... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - June 24, 2019 Category: Complementary Medicine Source Type: research

Fungistatic activity of essential oils for the control of bipolaris leaf spot in maize
Research institutions have emphasized alternative disease control agents because they represent a great option with beneficial effects on human and animal health and ecosystem balance. Despite the studies already done on botanical fungicides, their effective use requires knowledge about the applicability of natural products to different production systems. The main objective of this study is... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - June 24, 2019 Category: Complementary Medicine Source Type: research

Evaluation of the in vivo antiplasmodial activity of ethanol leaf extract and fractions of Jatropha gossypifolia in Plasmodium berghei infected mice
The study evaluates the in vivo antiplasmodial activity of ethanol leaf extract and fractions of Jatropha gossypifolia in Plasmodium berghei infected mice. Phytochemical, physicochemical analyses, median lethal dose (LD50), effects on biochemical parameter were evaluated and the schizonticidal effects during early and established infections were investigated. The extract (50-200 mg/kg) was s... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - June 9, 2019 Category: Complementary Medicine Source Type: research

Chemical fingerprint of Bacopa monnieri L. and Rosmarinus officinalis L. and their neuroprotective activity against Alzheimer's disease in rat model ’ s putative modulation via cholinergic and monoaminergic pathways
This study aims to characterize the metabolic profiles of the hydro-ethanolic extracts of Bacopa monnieri L. (BM) and Rosmarinus officinalis L. (RO) cultivated in Egypt via UPLCESI/MS analyses and reveal their possible mechanism of the prophylactic effect(s) on neuro-degeneration in rat model... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - June 9, 2019 Category: Complementary Medicine Source Type: research

In vitro evaluation of fruit extracts of Annona stenophylla diels and Flacourtia indica for incorporation into formulations for management of cancer
There are many reports which show a positive relationship between free radical damage and diseases such as cancer. Free radicals are formed when humans are exposed to ionizing radiation or during oxidation process in human beings can damage tissues and may potentially lead to development of cancers. Since radiation may be used in the management of cancer, there is need for the development of... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - June 9, 2019 Category: Complementary Medicine Source Type: research

Antihistaminic action of Melaleuca armillaris ointment
The objective is to develop a product based on Melaleuca armillaris to evaluate its antihistaminic action and to compare the antihistaminic effect and protective effect of M. armillaris oil and ointment. Pruritus intensity was assessed at sensitization points. Eighty volunteers, aged between 21 and 60 years (male and female) participated in the s... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - May 24, 2019 Category: Complementary Medicine Source Type: research

In vitro anti-inflammatory activity of ginger (Zingiber officinale Rosc.) rhizome, callus and callus treated with some elicitors
This study evaluated the effect of ginger rhizome and its callus as well as callus elicited by yeast extract, glycine and salicylic acid on the production of pro-inflammatory (TNF-, IL-1 and IL-6) and anti-inflammatory (IL-10 and TGF-) cytokines in vitro. Petroleum ether (PE) and chloroform; methanol (1:1) (CM) extracts of rhizome and callus were shown to significantly (P 0.05) suppress in ... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - May 24, 2019 Category: Complementary Medicine Source Type: research

A review of Ginseng species in different regions as a multipurpose herb in traditional Chinese medicine, modern herbology and pharmacological science
Ginseng is the most famous of the Chinese herbs throughout the world, and has been one of the most valued herb in China. Traditional Chinese medicine as an essential element of alternative and complementary medicine, advanced over thousands of years with its own distinctive arrangement of therapies, diagnostics theories and in Asian countries, particularly China. In most parts of the world, ... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - May 24, 2019 Category: Complementary Medicine Source Type: research