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Peptide targets to SARS-CoV-2
Santi M MandalJournal of Global Infectious Diseases 2020 12(4):234-235 (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Santi M Mandal Source Type: research

Recurrent Staphylococcus lugdunensis osteomyelitis of the lumbar spine in a patient on chronic hemodialysis
We report the case of a Caucasian elderly male with recurrent lumbar osteomyelitis due to S. lugdunensis. He had a history of chronic low back pain. Besides chronic kidney failure and need for hemodialysis, he had no other history of immunosuppression. He did not have fever or leukocytosis; however, the erythrocyte sedimentation rate was elevated, and repeated blood cultures from the periphery and the hemodialysis access (tunneled catheter) were continuously positive for S. lugdunensis. The diagnosis was made by bone biopsy and culture. The bacteremia cleared after removing of the dialysis catheter. The patient received 8 ...
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Yamil E Michelen Zeena Lobo Daniel Walshon-Dipillo George Psevdos Source Type: research

An unusual cause of adult ileoileal intussusception
Mohamed Javid, Shanthi Ponnandai Swaminathan, Rajeswari Mani, Arun Victor JebasinghJournal of Global Infectious Diseases 2020 12(4):228-230Intestinal intussusception in adults is not considered to be common. Clinical presentations may range from an acute presentation to a chronic one and such wide variations make it challenging to establish the diagnosis on time. Adult intussusceptions usually have an identifiable pathological lead point: commonly a polyp, submucosal lipoma, or other tumors. Our patient, a 42-year-old male, presented to us with features of acute intestinal obstruction. He underwent an emergency laparotomy ...
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Mohamed Javid Shanthi Ponnandai Swaminathan Rajeswari Mani Arun Victor Jebasingh Source Type: research

Neonatal meningitis and septicemia caused by multidrug-resistant Elizabethkingia anophelis identified by 16s ribosomal RNA: An emerging threat
Frincy K Baruah, Biswajyoti Borkakoty, Abid Ahmed, Prakritish BoraJournal of Global Infectious Diseases 2020 12(4):225-227Elizabethkingia anophelis infections are emerging, especially among premature newborns, immunocompromised, and critically ill patients. The importance of correctly identifying this Gram-negative organism lies in the fact that it is associated with fatal complications such as meningitis, acute pulmonary edema, congestive cardiac failure, septic shock, and death. In addition, it is inherently resistant to multiple antibiotics which are used to treat Gram-negative bacilli. Here, we report a case of E. anop...
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Frincy K Baruah Biswajyoti Borkakoty Abid Ahmed Prakritish Bora Source Type: research

Colchicine, aspirin, and montelukast & #8211; A case of successful combined pharmacotherapy for adult multisystem inflammatory syndrome in COVID-19
Sean Downing, Vivek Chauhan, Irshad H Chaudry, Sagar Galw.ar, Pushpa Sharma, Stanislaw P StawickiJournal of Global Infectious Diseases 2020 12(4):221-224Since the beginning of the COVID-19 pandemic, many therapeutic strategies have been tried, with mixed results, to prevent and treat adult multisystem inflammatory syndrome in COVID-19 (AMIS-COVID-19). The reason behind this may the complex web of highly intertwined pathophysiologic mechanisms involved in the SARS-CoV-2 infection and the corresponding human systemic response, leading to end-organ damage, disability, and death. Colchicine, high-dose aspirin, and montelukast ...
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Sean Downing Vivek Chauhan Irshad H Chaudry Sagar Galwankar Pushpa Sharma Stanislaw P Stawicki Source Type: research

Nontyphoid Salmonella empyema in a patient with type 2 diabetes mellitus
We report the case of a 56-year-old male with uncontrolled diabetes mellitus presenting with a multiloculated empyema due to NTS involving the left oblique pulmonary fissure. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Dipesh Solanky Brian Kwan Source Type: research

Inhibitory effect of zinc sulfate on clinical isolates of Pseudomonas aeruginosa and Acinetobacter baumannii
Ishaan Ramdas, C Sheela DeviJournal of Global Infectious Diseases 2020 12(4):217-218This objective of the study was to determine the inhibitory effect of zinc sulfate against the clinical isolates of Pseudomonas aeruginosa and Acinetobacter baumannii. The inhibitory effect of zinc sulfate was determined against the 120 clinical isolates (60 isolates of P. aeruginosa and 60 isolates of A. baumannii) by agar dilution method. The findings indicate that zinc has an inhibitory effect on the clinical isolates of P. aeruginosa and A. baumannii at a concentration ranging from 0.25to 1mg/ml of zinc sulfate by agar dilution method. ...
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Ishaan Ramdas C Sheela Devi Source Type: research

Hepatitis E virus infection among asymptomatic pregnant women at the University College Hospital, Ibadan
Conclusion: Recent HEV infection among this pregnant population is on the lower part of the scale, compared with other Sub-Saharan African countries. However, the HEV IgG seroprevalence rate suggests indirect evidence of past contact with HEV. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Adeola Fowotade Gloria Chinenye Anaedobe Olubukola A Adesina Source Type: research

A hospital-based nonconcurrent cohort study on factors associated with in-hospital mortality in patients with laboratory confirmed influenza
Conclusions: Our study showed a mortality of 12.3% (n= 16) and new onset/worsening renal dysfunction was the only patient factor associated with mortality. Early recognition of complications and appropriate treatment may reduce mortality in patients admitted with severe influenza. We recommend influenza vaccination for at-risk populations to reduce severity and mortality. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Vijay Alexander G Jackwin Sam Paul Anand Zachariah Alice Joan Mathuram Source Type: research

Incidence, risk factors and clinical outcomes of patients with hypermucoviscoid Klebsiella in a tertiary intensive care unit
Conclusions: Our study results showed, increased incidence of HAI with hvKP predominantly associated with pneumonia and increase in trend of drug resistance with two cases being pan resistant. More number of studies are required to evaluate the existing antibiotics strategy and steps to curb the spread of this dreaded infection. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Vimal Bhardwaj Vellaichamy Muthupandi Annapandian Annie Rofeena Sinazer Arjun Alva Shiva Prasad Source Type: research

Prevalence of hepatitis delta virus infection among hepatitis B virus-infected and exposed patients
Conclusion: The present study provides evidence that HDV infection is very low(0.78%) in this part of India. However further prospective studies with larger sample size are warranted. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Krithiga Ramachandran Reshu Agarwal Manoj Kumar Sharma Vikram Bhatia Ekta Gupta Source Type: research

A clinicohistopathological correlation of Hansen & #39;s disease in a rural tertiary care hospital of Central India
Conclusion: Clinical diagnosis of early leprosy lesions offers difficulties even to experienced dermatologists as a patient presents in different clinicopathological forms, depending on host immune status. Thus, the correlation between clinical, histopathological, and bacteriological features is required for diagnosis and classification of leprosy. Nerve damage is irreversible; therefore, early detection and treatment is important to prevent Grade 2 disabilities. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Manisha A Atram Pravinkumar V Ghongade Nitin M Gangane Source Type: research

COVID-19 blind spots: A consensus statement on the importance of competent political leadership and the need for public health cognizance
Thomas J Papadimos, Samara E Soghoian, Prabath Nanayakkara, Sarman Singh, Andrew C Miller, Venkataramanaiah Saddikuti, Achala Upendra Jayatilleke, Siddharth P Dubhashi, Michael S Firstenberg, Vibha Dutta, Vivek Chauhan, Pushpa Sharma, Sagar C Galw.ar, Manish Garg, Nicholas Taylor, Stanislaw P StawickiJournal of Global Infectious Diseases 2020 12(4):167-190 As the COVID-19 pandemic continues, important discoveries and considerations emerge regarding the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pathogen; its biological and epidemiological characteristics; and the corresponding psychological, societal, an...
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Thomas J Papadimos Samara E Soghoian Prabath Nanayakkara Sarman Singh Andrew C Miller Venkataramanaiah Saddikuti Achala Upendra Jayatilleke Siddharth P Dubhashi Michael S Firstenberg Vibha Dutta Vivek Chauhan Pushpa Sharma Sagar C Galwankar Manish Garg Ni Source Type: research

State of the globe: & #8220;Hansen & #39;s disease & #8211; Down but not out in the SARS-CoV-2 era & #8221;
Suman Thakur, Vivek ChauhanJournal of Global Infectious Diseases 2020 12(4):165-166 (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Suman Thakur Vivek Chauhan Source Type: research

Over 8000 macaque bites since 2014 but no herpes B virus infection reported from Shimla, India
Suman Thakur, Vivek Chauhan, Kamlesh Sharma, Mrinalini SinghJournal of Global Infectious Diseases 2020 12(3):163-164 (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - August 28, 2020 Category: Infectious Diseases Authors: Suman Thakur Vivek Chauhan Kamlesh Sharma Mrinalini Singh Source Type: research