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Unusual presentations of abdominal melioidosis
We present two cases of abdominal melioidosis with unusual clinical presentations. The first case presented with intractable hiccups and had isolated splenic melioidosis with contained rupture. The second case presented with fever and acute abdominal pain found to have pancreatic melioidosis and splenic vein thrombosis. Both the patients were treated with IV antibiotics and subsequently discharged after improvement in symptoms. The imaging findings of isolated type of melioidosis can mimic various other infections and granulomatous disease. Hence high index of clinical suspicion for patients presenting from endemic areas w...
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Vignesh Kumar Mohan Komalavalli Rajesh Sripriya Srinivas R Ravi Jimmy Prabhakaran K Srinivasan Subha Sundaramoorthy Source Type: research

Intravenous immunoglobulin for overwhelming postsplenectomy infection
Kensuke Nakamura, Yuji Takahashi, Tomohiro Sonoo, Hideki HashimotoJournal of Global Infectious Diseases 2021 13(1):44-51Overwhelming postsplenectomy infection (OPSI) is a life-threatening condition causing fulminant bacteremia in asplenic patients. Intravenous immunoglobulin (IVIG) therapy is theoretically effective for OPSI. Herein, we present a case of OPSI treated successfully with IVIG, along with results of a literature review. An asplenic 70-year-old male with acute ischemic stroke presented with rapid and fulminant septic shock from pneumococcus pneumonia and bacteremia. Resuscitation and antibiotics including IVIG ...
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Kensuke Nakamura Yuji Takahashi Tomohiro Sonoo Hideki Hashimoto Source Type: research

Positive SARS-CoV-2 RNA with significant inflammatory state and thrombophilia after 12 weeks of initial diagnosis of COVID-19 infection
Manuel Francisco Betancourt, Kimberly Michelle Grant, James Scott Johnson, Dhanashree S Kelkar, Kamal SharmaJournal of Global Infectious Diseases 2021 13(1):42-43The ongoing COVID-19 pandemic has affected most countries in the world, with significant economic and public health implications. There is rising concern that patients who recover from COVID-19 may be at risk of reinfection. Another potential concern is the uncommon clinical scenario of a patient having persistent SARS-CoV-2 RNA test over 3 months after the initial COVID-19 infection, as the patient presented. Whether presenting as a long-term infection (12 weeks)...
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Manuel Francisco Betancourt Kimberly Michelle Grant James Scott Johnson Dhanashree S Kelkar Kamal Sharma Source Type: research

Persistent hypercoagulable state in COVID-19: A case series of COVID-19 associated pulmonary embolism
Kok Hoe Chan, Su Lin Lim, Hamid Shaaban, Gunwant Guron, Jihad SlimJournal of Global Infectious Diseases 2021 13(1):38-41Coronavirus disease 2019 (COVID-19) has swept through the world with millions of cases and hundreds of thousands of deaths. COVID-19-associated coagulopathy has been recognized as the major cause of morbidity and mortality. To the best of our knowledge, a majority of the cases of coagulopathy have been reported in patients with moderate-to-severe COVID-19 and limited to observations during the recovery/postcytokine storm state. Herein, we report a case series of two patients with COVID-19 who developed pu...
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Kok Hoe Chan Su Lin Lim Hamid Shaaban Gunwant Guron Jihad Slim Source Type: research

Spina Ventosa: An often Missed Diagnosis
Ankur Agarwal, Sheetal Agarwal, Savitri Singh, Sumi NandwaniJournal of Global Infectious Diseases 2021 13(1):36-37Rare and varied presentations of tuberculosis make it difficult for treating clinicians to arrive at the diagnosis. An adolescent female presented to the orthopedic outpatient department with slowly increasing swelling over the dorsum of the hand near the base of the third digit for 5 months. With multiple consultations, she was being treated with antibiotics as a case of abscess. On examination, the swelling was soft bulging with whitish watery discharge. Plain radiography revealed periosteal elevation with bo...
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Ankur Agarwal Sheetal Agarwal Savitri Singh Sumi Nandwani Source Type: research

Nonsevere acute respiratory syndrome human coronaviruses in children hospitalized with acute lower respiratory infection
Conclusions: HCoV is an uncommon but increasingly recognized cause of ALRI in hospitalized children. No severe illness was found in children with underlying comorbidities. This study underscores the importance of HCoV in causation of childhood ALRI, necessitating a surveillance system in India. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Rashmi Ranjan Das Mohamed Fajrudheen Monalisa Mohanty Joseph John Sutapa Rath Amit Kumar Satapathy Bhagirathi Dwibedi Baijayantimala Mishra Source Type: research

Legal and environmental implications of COVID & #8209;19 outbreak in India
Nancy Maurya, Devendra DwargJournal of Global Infectious Diseases 2021 13(1):27-32The present work is an attempt to look at the legal and environmental implications of coronavirus disease-2019 outbreak in India. It looks at both sides of this tragedy focusing specifically on the environmental and legal aspects in the Indian context. However, the article does not refrain from discussing examples of other countries or some global aspects if necessary. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Nancy Maurya Devendra Dwarg Source Type: research

Maternal and perinatal outcomes of influenza in pregnancy after treatment with oseltamivir
Conclusion: Influenza in pregnancy showed year-round incidence and increased maternal and neonatal morbidity despite treatment with oseltamivir. We suggest the need for newer interventions to curtail the illness in pregnancy. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Kavitha Abraham Anuja Abraham Annie Regi Jessie Lionel Elsy Thomas Reeta Vijayaselvi L Jeyaseelan Asha Mary Abraham Sridhar Santhanam Kurian Anil Kuruvilla Mark C Steinhoff Source Type: research

Clinical determinants of severe COVID-19 disease & #8211; A systematic review and meta-analysis
Conclusion: Our analysis describes the association of specific symptoms and comorbidities with severe COVID-19 disease. Knowledge of these clinical determinants will assist the clinicians in the risk-stratification of these patients for better triage and clinical management. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Ankit Kumar Sahu Roshan Mathew Praveen Aggarwal Jamshed Nayer Sanjeev Bhoi Swayamjeet Satapathy Meera Ekka Source Type: research

Nocardiosis at an organ transplant center in Saudi Arabia: 15 years & #39; experience
Conclusion: Wider use of immunosuppressive therapy warrants vigilance to nocardiosis, which can present in a myriad of clinical forms. In our series, mortality was confined to the transplantation group, probably because of the relatively heavy immunosuppression. Nonetheless, prognosis is favorable if the infection is recognized and treated early. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Ihab Weheba Abeer Abdelsayed Abdulrahman A Alrajhi Sahar I Al-Thawadi Abdullah Mobeireek Source Type: research

Adolescent females are more susceptible than males for tuberculosis
Conclusions: Significant gender difference with female susceptibility was seen for TB among adolescents, a fact that needs more research. Adolescent TB is a neglected area with little published data driven mainly by the fact that most countries report their TB population above and below 15 years, dividing the adolescent population into two halves. The world needs to acknowledge adolescents (10–19 years) as a separate important group for reporting TB statistics. (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Suman Thakur Vivek Chauhan Ravinder Kumar Gopal Beri Source Type: research

State of the globe: Addressing gender in adolescent tuberculosis
Sunil Kumar RainaJournal of Global Infectious Diseases 2021 13(1):1-2 (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - February 26, 2021 Category: Infectious Diseases Authors: Sunil Kumar Raina Source Type: research

Splenic infarction complicating scrub typhus
Ashwini Tayade, Sourya Acharya, Nikhil Balankhe, Aishwarya Ghule, Swapnil LaholeJournal of Global Infectious Diseases 2020 12(4):238-239 (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Ashwini Tayade Sourya Acharya Nikhil Balankhe Aishwarya Ghule Swapnil Lahole Source Type: research

Detection of Mycobacterium Tuberculosis and rifampicin-resistant gene among hemodialysis patients in Khartoum, Sudan: Using GeneXpert assay
Balsam Adil Mohamed, Mohammed H Ahmed, Nadir AbuzeidJournal of Global Infectious Diseases 2020 12(4):236-237 (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Balsam Adil Mohamed Mohammed H Ahmed Nadir Abuzeid Source Type: research

Comparison of conventional versus molecular semi-quantitative assay in presumptive pulmonary tuberculosis cases: A study from eastern India
Geetarani Purohit, Baijayantimala Mishra, Prasanta Raghab MohapatraJournal of Global Infectious Diseases 2020 12(4):235-236 (Source: Journal of Global Infectious Diseases)
Source: Journal of Global Infectious Diseases - November 30, 2020 Category: Infectious Diseases Authors: Geetarani Purohit Baijayantimala Mishra Prasanta Raghab Mohapatra Source Type: research