Unveiling the Gastrointestinal Microbiome Symphony: Insights Into Post-Gastric Cancer Treatment Microbial Patterns and Potential Therapeutic Avenues
In conclusion, understanding the intricate interplay between the gastrointestinal microbiome and gastric cancer treatment offers prospects for predicting responses and enhancing postoperative recovery. Probiotics, with their positive impact on inflammation and immunity, have emerged as potential adjuncts in patient care. Continued research is imperative to fully harness the potential of microbiome-based interventions in the management of gastric cancer.PMID:38225768 | PMC:PMC10774752 | DOI:10.5230/jgc.2024.24.e4 (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Chan Hyuk Park Source Type: research
Risk Factors of Gastric Cancer and Lifestyle Modification for Prevention
In this study, we aim to review the risk factors for gastric cancer with respect to cardia and non-cardia types. One of the most significant risk factors for gastric cancer is Helicobacter pylori infection. H. pylori infection is known as a risk factor for non-cardia gastric cancer, and there have been results indicating that H. pylori infection is not associated with cardia gastric cancer. However, in the East Asian region, there is epidemiological evidence suggesting that H. pylori infection might be a risk factor for cardia gastric cancer. Smoking and alcohol consumption are known risk factors for gastric cancer, regard...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Kwang-Pil Ko Source Type: research
Endoscopic Intervention for Anastomotic Leakage After Gastrectomy
J Gastric Cancer. 2024 Jan;24(1):108-121. doi: 10.5230/jgc.2024.24.e12.ABSTRACTAnastomotic leaks and fistulas are significant complications of gastric surgery that potentially lead to increased postoperative morbidity and mortality. Surgical intervention is reserved for cases with severe symptoms or hemodynamic instability; however, surgery carries a higher risk of complications. With advancements in endoscopic treatment options, endoscopic approaches have emerged as the primary choice for managing these complications. Endoscopic clipping is a traditional method comprising 2 main categories: through-the-scope clips and ove...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Ji Yoon Kim Hyunsoo Chung Source Type: research
Endoscopic Treatment for Gastric Subepithelial Tumor
This study aimed to discuss the indications, methods, and outcomes of endoscopic therapy for gastric SETs. In addition, a simplified diagram of the category of SETs according to the therapeutic indications and an algorithm for the endoscopic management of SET is suggested.PMID:38225771 | PMC:PMC10774759 | DOI:10.5230/jgc.2024.24.e11 (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Chan Gyoo Kim Source Type: research
Latest Insights From Multiple Disciplinary Approaches to Manage Gastric Cancer
J Gastric Cancer. 2024 Jan;24(1):1-3. doi: 10.5230/jgc.2024.24.e8.NO ABSTRACTPMID:38225763 | PMC:PMC10774757 | DOI:10.5230/jgc.2024.24.e8 (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Ki Bum Park Han Hong Lee Source Type: research
Liquid Biopsy: An Emerging Diagnostic, Prognostic, and Predictive Tool in Gastric Cancer
J Gastric Cancer. 2024 Jan;24(1):4-28. doi: 10.5230/jgc.2024.24.e5.ABSTRACTLiquid biopsy, a minimally invasive procedure that causes minimal pain and complication risks to patients, has been extensively studied for cancer diagnosis and treatment. Moreover, it facilitates comprehensive quantification and serial assessment of the whole-body tumor burden. Several biosources obtained through liquid biopsy have been studied as important biomarkers for establishing early diagnosis, monitoring minimal residual disease, and predicting the prognosis and response to treatment in patients with cancer. Although the clinical applicatio...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Hye Sook Han Keun-Wook Lee Source Type: research
Emerging Targets for Systemic Treatment of Gastric Cancer: HER2 and Beyond
J Gastric Cancer. 2024 Jan;24(1):29-56. doi: 10.5230/jgc.2024.24.e6.ABSTRACTIn recent years, remarkable progress has been made in the molecular profiling of gastric cancer. This progress has led to the development of various molecular classifications to uncover subtype-specific dependencies that can be targeted for therapeutic interventions. Human epidermal growth factor receptor 2 (HER2) is a crucial biomarker for advanced gastric cancer. The recent promising results of novel approaches, including combination therapies or newer potent agents such as antibody-drug conjugates, have once again brought attention to anti-HER2 ...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: In-Ho Kim Source Type: research
Current Issues in Reduced-Port Gastrectomy: A Comprehensive Review
J Gastric Cancer. 2024 Jan;24(1):57-68. doi: 10.5230/jgc.2024.24.e9.ABSTRACTReduced-port gastrectomy (RPG) includes all procedures derived from various efforts to minimize surgical invasiveness, with single-incision laparoscopic gastrectomy (SILG) being the ultimate reduced-port technique. However, there are challenges related to its feasibility, oncological validity, training, and education. This review describes the current issues and challenges, as well as the future prospects of RPG for gastric cancer. Gastrectomy, which started as an open surgery, has evolved into a laparoscopic surgery. With the advancements in lapar...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Jong Won Kim Source Type: research
Unusual or Uncommon Histology of Gastric Cancer
J Gastric Cancer. 2024 Jan;24(1):69-88. doi: 10.5230/jgc.2024.24.e7.ABSTRACTThis review comprehensively examines the diverse spectrum of gastric cancers, focusing on unusual or uncommon histology that presents significant diagnostic and therapeutic challenges. While the predominant form, tubular adenocarcinoma, is well-characterized, this review focuses on lesser-known variants, including papillary adenocarcinoma, micropapillary carcinoma, adenosquamous carcinoma, squamous cell carcinoma (SCC), hepatoid adenocarcinoma, gastric choriocarcinoma, gastric carcinoma with lymphoid stroma, carcinosarcoma, gastroblastoma, parietal...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Jinho Shin Young Soo Park Source Type: research
Unveiling the Gastrointestinal Microbiome Symphony: Insights Into Post-Gastric Cancer Treatment Microbial Patterns and Potential Therapeutic Avenues
In conclusion, understanding the intricate interplay between the gastrointestinal microbiome and gastric cancer treatment offers prospects for predicting responses and enhancing postoperative recovery. Probiotics, with their positive impact on inflammation and immunity, have emerged as potential adjuncts in patient care. Continued research is imperative to fully harness the potential of microbiome-based interventions in the management of gastric cancer.PMID:38225768 | PMC:PMC10774752 | DOI:10.5230/jgc.2024.24.e4 (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Chan Hyuk Park Source Type: research
Risk Factors of Gastric Cancer and Lifestyle Modification for Prevention
In this study, we aim to review the risk factors for gastric cancer with respect to cardia and non-cardia types. One of the most significant risk factors for gastric cancer is Helicobacter pylori infection. H. pylori infection is known as a risk factor for non-cardia gastric cancer, and there have been results indicating that H. pylori infection is not associated with cardia gastric cancer. However, in the East Asian region, there is epidemiological evidence suggesting that H. pylori infection might be a risk factor for cardia gastric cancer. Smoking and alcohol consumption are known risk factors for gastric cancer, regard...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Kwang-Pil Ko Source Type: research
Endoscopic Intervention for Anastomotic Leakage After Gastrectomy
J Gastric Cancer. 2024 Jan;24(1):108-121. doi: 10.5230/jgc.2024.24.e12.ABSTRACTAnastomotic leaks and fistulas are significant complications of gastric surgery that potentially lead to increased postoperative morbidity and mortality. Surgical intervention is reserved for cases with severe symptoms or hemodynamic instability; however, surgery carries a higher risk of complications. With advancements in endoscopic treatment options, endoscopic approaches have emerged as the primary choice for managing these complications. Endoscopic clipping is a traditional method comprising 2 main categories: through-the-scope clips and ove...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Ji Yoon Kim Hyunsoo Chung Source Type: research
Endoscopic Treatment for Gastric Subepithelial Tumor
This study aimed to discuss the indications, methods, and outcomes of endoscopic therapy for gastric SETs. In addition, a simplified diagram of the category of SETs according to the therapeutic indications and an algorithm for the endoscopic management of SET is suggested.PMID:38225771 | PMC:PMC10774759 | DOI:10.5230/jgc.2024.24.e11 (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Chan Gyoo Kim Source Type: research
Latest Insights From Multiple Disciplinary Approaches to Manage Gastric Cancer
J Gastric Cancer. 2024 Jan;24(1):1-3. doi: 10.5230/jgc.2024.24.e8.NO ABSTRACTPMID:38225763 | PMC:PMC10774757 | DOI:10.5230/jgc.2024.24.e8 (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Ki Bum Park Han Hong Lee Source Type: research
Liquid Biopsy: An Emerging Diagnostic, Prognostic, and Predictive Tool in Gastric Cancer
J Gastric Cancer. 2024 Jan;24(1):4-28. doi: 10.5230/jgc.2024.24.e5.ABSTRACTLiquid biopsy, a minimally invasive procedure that causes minimal pain and complication risks to patients, has been extensively studied for cancer diagnosis and treatment. Moreover, it facilitates comprehensive quantification and serial assessment of the whole-body tumor burden. Several biosources obtained through liquid biopsy have been studied as important biomarkers for establishing early diagnosis, monitoring minimal residual disease, and predicting the prognosis and response to treatment in patients with cancer. Although the clinical applicatio...
Source: Journal of Gastric Cancer - January 16, 2024 Category: Gastroenterology Authors: Hye Sook Han Keun-Wook Lee Source Type: research
