Assessment of body fluid identification and DNA profiling after exposure to tropical weather conditions
In conclusion, this study demonstrated for the first time the possibility of body fluid identification and DNA profiling after exposure to tropical weather conditions for 1 month and also demonstrated the value of mtDNA analysis for compromised biological evidence.PMID:38146797 | DOI:10.1111/1556-4029.15453 (Source: Journal of Forensic Sciences)
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Sara C Zapico Christian Stadler Gabriela Roca Source Type: research

Phenibut screening and quantification with liquid chromatography-tandem mass spectrometry and its application to driving cases
J Forensic Sci. 2023 Dec 26. doi: 10.1111/1556-4029.15455. Online ahead of print.ABSTRACTAn analytical strategy for identification by an LC-MS/MS multitarget screening method and a suitable LC-MS/MS based quantification were developed for the psychotropic drug phenibut. The samples analyzed were collected during traffic control and were associated with driving under the influence of drugs. A positive sample for phenibut was identified in a single case of driving under the influence. The quantification revealed a drug concentration of 1.9 μg/mL. An interaction with blood alcohol (BAC = 0.10%) was discussed as the explanati...
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Marek Dziadosz Wolfgang Rosenberger Katarina Bolte Michael Klintschar J örg Teske Source Type: research

Assessment of body fluid identification and DNA profiling after exposure to tropical weather conditions
In conclusion, this study demonstrated for the first time the possibility of body fluid identification and DNA profiling after exposure to tropical weather conditions for 1 month and also demonstrated the value of mtDNA analysis for compromised biological evidence.PMID:38146797 | DOI:10.1111/1556-4029.15453 (Source: Journal of Forensic Sciences)
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Sara C Zapico Christian Stadler Gabriela Roca Source Type: research

Phenibut screening and quantification with liquid chromatography-tandem mass spectrometry and its application to driving cases
J Forensic Sci. 2023 Dec 26. doi: 10.1111/1556-4029.15455. Online ahead of print.ABSTRACTAn analytical strategy for identification by an LC-MS/MS multitarget screening method and a suitable LC-MS/MS based quantification were developed for the psychotropic drug phenibut. The samples analyzed were collected during traffic control and were associated with driving under the influence of drugs. A positive sample for phenibut was identified in a single case of driving under the influence. The quantification revealed a drug concentration of 1.9 μg/mL. An interaction with blood alcohol (BAC = 0.10%) was discussed as the explanati...
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Marek Dziadosz Wolfgang Rosenberger Katarina Bolte Michael Klintschar J örg Teske Source Type: research

Assessment of body fluid identification and DNA profiling after exposure to tropical weather conditions
In conclusion, this study demonstrated for the first time the possibility of body fluid identification and DNA profiling after exposure to tropical weather conditions for 1 month and also demonstrated the value of mtDNA analysis for compromised biological evidence.PMID:38146797 | DOI:10.1111/1556-4029.15453 (Source: Journal of Forensic Sciences)
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Sara C Zapico Christian Stadler Gabriela Roca Source Type: research

Phenibut screening and quantification with liquid chromatography-tandem mass spectrometry and its application to driving cases
J Forensic Sci. 2023 Dec 26. doi: 10.1111/1556-4029.15455. Online ahead of print.ABSTRACTAn analytical strategy for identification by an LC-MS/MS multitarget screening method and a suitable LC-MS/MS based quantification were developed for the psychotropic drug phenibut. The samples analyzed were collected during traffic control and were associated with driving under the influence of drugs. A positive sample for phenibut was identified in a single case of driving under the influence. The quantification revealed a drug concentration of 1.9 μg/mL. An interaction with blood alcohol (BAC = 0.10%) was discussed as the explanati...
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Marek Dziadosz Wolfgang Rosenberger Katarina Bolte Michael Klintschar J örg Teske Source Type: research

Assessment of body fluid identification and DNA profiling after exposure to tropical weather conditions
In conclusion, this study demonstrated for the first time the possibility of body fluid identification and DNA profiling after exposure to tropical weather conditions for 1 month and also demonstrated the value of mtDNA analysis for compromised biological evidence.PMID:38146797 | DOI:10.1111/1556-4029.15453 (Source: Journal of Forensic Sciences)
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Sara C Zapico Christian Stadler Gabriela Roca Source Type: research

Phenibut screening and quantification with liquid chromatography-tandem mass spectrometry and its application to driving cases
J Forensic Sci. 2023 Dec 26. doi: 10.1111/1556-4029.15455. Online ahead of print.ABSTRACTAn analytical strategy for identification by an LC-MS/MS multitarget screening method and a suitable LC-MS/MS based quantification were developed for the psychotropic drug phenibut. The samples analyzed were collected during traffic control and were associated with driving under the influence of drugs. A positive sample for phenibut was identified in a single case of driving under the influence. The quantification revealed a drug concentration of 1.9 μg/mL. An interaction with blood alcohol (BAC = 0.10%) was discussed as the explanati...
Source: Journal of Forensic Sciences - December 26, 2023 Category: Forensic Medicine Authors: Marek Dziadosz Wolfgang Rosenberger Katarina Bolte Michael Klintschar J örg Teske Source Type: research

Quantification of psilocin in human whole blood using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
J Forensic Sci. 2023 Dec 22. doi: 10.1111/1556-4029.15454. Online ahead of print.ABSTRACTThere has been burgeoning interest in psilocybin-use for the treatment of various neurological and neurodegenerative diseases. Psilocybin is mistakenly perceived as the principal pharmacologically active compound due to its high concentrations found in magic mushrooms; however, it is the prodrug of psilocin. Despite the expanding body of clinical research seeking to understand the pharmacodynamic/pharmacokinetic properties of psilocin, and its role in inducing dramatic changes to cognitive function, there has not been a corresponding i...
Source: Journal of Forensic Sciences - December 23, 2023 Category: Forensic Medicine Authors: Munchelou M Gomonit Britni Skillman Madeleine J Swortwood Source Type: research

Cutaneous skin defects overlying tangential gunshot wounds: A case series
J Forensic Sci. 2023 Dec 22. doi: 10.1111/1556-4029.15458. Online ahead of print.ABSTRACTIn examining deaths resulting from gunshot wounds, it is important to describe the wound pathway created by the projectile. Forensic pathologists must identify all entrance and exit wounds and account for all projectiles. Occasionally, confusion arises as to whether a skin defect represents an entrance wound or not, an exit wound, or some other type of wound. Herein, we propose the descriptor "bullet track skin defect" as a formal description for a superficial skin defect created along the pathway of a projectile within the body. Speci...
Source: Journal of Forensic Sciences - December 23, 2023 Category: Forensic Medicine Authors: Nikoli M Nickson Joyce L DeJong Jared K Brooks Joseph A Prahlow Source Type: research

Quantification of psilocin in human whole blood using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
J Forensic Sci. 2023 Dec 22. doi: 10.1111/1556-4029.15454. Online ahead of print.ABSTRACTThere has been burgeoning interest in psilocybin-use for the treatment of various neurological and neurodegenerative diseases. Psilocybin is mistakenly perceived as the principal pharmacologically active compound due to its high concentrations found in magic mushrooms; however, it is the prodrug of psilocin. Despite the expanding body of clinical research seeking to understand the pharmacodynamic/pharmacokinetic properties of psilocin, and its role in inducing dramatic changes to cognitive function, there has not been a corresponding i...
Source: Journal of Forensic Sciences - December 23, 2023 Category: Forensic Medicine Authors: Munchelou M Gomonit Britni Skillman Madeleine J Swortwood Source Type: research

Cutaneous skin defects overlying tangential gunshot wounds: A case series
J Forensic Sci. 2023 Dec 22. doi: 10.1111/1556-4029.15458. Online ahead of print.ABSTRACTIn examining deaths resulting from gunshot wounds, it is important to describe the wound pathway created by the projectile. Forensic pathologists must identify all entrance and exit wounds and account for all projectiles. Occasionally, confusion arises as to whether a skin defect represents an entrance wound or not, an exit wound, or some other type of wound. Herein, we propose the descriptor "bullet track skin defect" as a formal description for a superficial skin defect created along the pathway of a projectile within the body. Speci...
Source: Journal of Forensic Sciences - December 23, 2023 Category: Forensic Medicine Authors: Nikoli M Nickson Joyce L DeJong Jared K Brooks Joseph A Prahlow Source Type: research

Quantification of psilocin in human whole blood using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
J Forensic Sci. 2023 Dec 22. doi: 10.1111/1556-4029.15454. Online ahead of print.ABSTRACTThere has been burgeoning interest in psilocybin-use for the treatment of various neurological and neurodegenerative diseases. Psilocybin is mistakenly perceived as the principal pharmacologically active compound due to its high concentrations found in magic mushrooms; however, it is the prodrug of psilocin. Despite the expanding body of clinical research seeking to understand the pharmacodynamic/pharmacokinetic properties of psilocin, and its role in inducing dramatic changes to cognitive function, there has not been a corresponding i...
Source: Journal of Forensic Sciences - December 23, 2023 Category: Forensic Medicine Authors: Munchelou M Gomonit Britni Skillman Madeleine J Swortwood Source Type: research

Cutaneous skin defects overlying tangential gunshot wounds: A case series
J Forensic Sci. 2023 Dec 22. doi: 10.1111/1556-4029.15458. Online ahead of print.ABSTRACTIn examining deaths resulting from gunshot wounds, it is important to describe the wound pathway created by the projectile. Forensic pathologists must identify all entrance and exit wounds and account for all projectiles. Occasionally, confusion arises as to whether a skin defect represents an entrance wound or not, an exit wound, or some other type of wound. Herein, we propose the descriptor "bullet track skin defect" as a formal description for a superficial skin defect created along the pathway of a projectile within the body. Speci...
Source: Journal of Forensic Sciences - December 23, 2023 Category: Forensic Medicine Authors: Nikoli M Nickson Joyce L DeJong Jared K Brooks Joseph A Prahlow Source Type: research

Experimental results on data analysis algorithms for extracting and interpreting edge feature data for duct tape and textile physical fit examinations
J Forensic Sci. 2023 Dec 18. doi: 10.1111/1556-4029.15449. Online ahead of print.ABSTRACTA physical fit is an important observation that can result from the forensic analysis of trace evidence as it conveys a high degree of association between two items. However, physical fit examinations can be time-consuming, and potential bias from analysts may affect judgment. To overcome these shortcomings, a data analysis algorithm using mutual information and a decision tree has been developed to support practitioners in interpreting the evidence. We created these tools using data obtained from physical fit examinations of duct tape...
Source: Journal of Forensic Sciences - December 19, 2023 Category: Forensic Medicine Authors: Meghan Prusinowski Pedram Tavadze Zachary Andrews Logan Lang Divyanjali Pulivendhan Cedric Neumann Aldo H Romero Tatiana Trejos Source Type: research