Mutational signatures for breast cancer diagnosis using artificial intelligence
This study sought to investigate the relationship between breast cancer genetic mutational profiles using artificial intelligence models with a view to developing an accurate prognostic prediction based on breast cancer genetic signatures. Prior research on breast cancer has been based on symptoms, origin, and tumor size. It has not been investigated whether diagnosis of breast cancer can be made utilizing AI platforms like Cytoscape, Phenolyzer, and Geneshot with potential for better prognostic power. This is the first ever attempt for a combinatorial approach to breast cancer diagnosis using different AI platforms.METHOD...
Source: J Egypt Natl Canc In... - May 15, 2023 Category: Cancer & Oncology Authors: Patrick Odhiambo Harrison Okello Annette Wakaanya Clabe Wekesa Patrick Okoth Source Type: research
Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research
Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research
Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research
Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research
Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research
Evaluation of short-term outcomes of neoadjuvant chemotherapy followed by radical cystectomy in muscle-invasive bladder cancer: a single Egyptian institution experience
CONCLUSIONS: Our results are further supporting the radiological and pathological benefits of NAC in MIBC, evidenced by tumor downstaging and pCR. The complication rate after RC is still considerable; hence, more larger studies are necessary to postulate a comprehensive risk assessment tool for patients who would get the maximum benefit from NAC, hoping to accomplish higher complete response rates with ultimately increased adoption of the bladder preservation strategies.PMID:37145329 | DOI:10.1186/s43046-023-00175-2 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 5, 2023 Category: Cancer & Oncology Authors: Ibrahim Abdelrahman Hatem Aboulkassem Abdallah Elazab Ahmed Younis Abdallah Yahia Ismail Mohammad Taher Source Type: research
Evaluation of short-term outcomes of neoadjuvant chemotherapy followed by radical cystectomy in muscle-invasive bladder cancer: a single Egyptian institution experience
CONCLUSIONS: Our results are further supporting the radiological and pathological benefits of NAC in MIBC, evidenced by tumor downstaging and pCR. The complication rate after RC is still considerable; hence, more larger studies are necessary to postulate a comprehensive risk assessment tool for patients who would get the maximum benefit from NAC, hoping to accomplish higher complete response rates with ultimately increased adoption of the bladder preservation strategies.PMID:37145329 | DOI:10.1186/s43046-023-00175-2 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 5, 2023 Category: Cancer & Oncology Authors: Ibrahim Abdelrahman Hatem Aboulkassem Abdallah Elazab Ahmed Younis Abdallah Yahia Ismail Mohammad Taher Source Type: research
Evaluation of short-term outcomes of neoadjuvant chemotherapy followed by radical cystectomy in muscle-invasive bladder cancer: a single Egyptian institution experience
CONCLUSIONS: Our results are further supporting the radiological and pathological benefits of NAC in MIBC, evidenced by tumor downstaging and pCR. The complication rate after RC is still considerable; hence, more larger studies are necessary to postulate a comprehensive risk assessment tool for patients who would get the maximum benefit from NAC, hoping to accomplish higher complete response rates with ultimately increased adoption of the bladder preservation strategies.PMID:37145329 | DOI:10.1186/s43046-023-00175-2 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 5, 2023 Category: Cancer & Oncology Authors: Ibrahim Abdelrahman Hatem Aboulkassem Abdallah Elazab Ahmed Younis Abdallah Yahia Ismail Mohammad Taher Source Type: research
Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research
Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research
Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research
Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research
Organ preservation strategy: new therapeutic alternative in rectal cancer
CONCLUSION: This nonoperative approach is currently widely studied in certain patients who have a complete response (clinical, endoscopic, and radiological). However, the selection of these patients is not simple and still complex.PMID:37093327 | PMC:PMC10123594 | DOI:10.1186/s43046-023-00169-0 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 24, 2023 Category: Cancer & Oncology Authors: F Safini B Amaoui S Semghouli N Aqodad Source Type: research
Organ preservation strategy: new therapeutic alternative in rectal cancer
CONCLUSION: This nonoperative approach is currently widely studied in certain patients who have a complete response (clinical, endoscopic, and radiological). However, the selection of these patients is not simple and still complex.PMID:37093327 | PMC:PMC10123594 | DOI:10.1186/s43046-023-00169-0 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 24, 2023 Category: Cancer & Oncology Authors: F Safini B Amaoui S Semghouli N Aqodad Source Type: research
