Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research

Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research

Programmed death ligand 1 expression in diffuse large B cell lymphoma: correlation with clinicopathological prognostic factors
CONCLUSIONS: This study suggests that high PD-L1 expression in DLBCL is associated with aggressive clinicopathological features and a decreased response to R-CHOP. The level of PD-L1 expression could be an independent predictor of DFS of DLBCL. More research is mandatory to standardize the cutoff value and scoring methods.PMID:37150782 | DOI:10.1186/s43046-023-00171-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 7, 2023 Category: Cancer & Oncology Authors: Eman Mohamad Ibrahim Sherine Refat Shaimaa El-Ashwah Maryan Waheeb Fahmi Afaf Taha Ibrahiem Source Type: research

Evaluation of short-term outcomes of neoadjuvant chemotherapy followed by radical cystectomy in muscle-invasive bladder cancer: a single Egyptian institution experience
CONCLUSIONS: Our results are further supporting the radiological and pathological benefits of NAC in MIBC, evidenced by tumor downstaging and pCR. The complication rate after RC is still considerable; hence, more larger studies are necessary to postulate a comprehensive risk assessment tool for patients who would get the maximum benefit from NAC, hoping to accomplish higher complete response rates with ultimately increased adoption of the bladder preservation strategies.PMID:37145329 | DOI:10.1186/s43046-023-00175-2 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 5, 2023 Category: Cancer & Oncology Authors: Ibrahim Abdelrahman Hatem Aboulkassem Abdallah Elazab Ahmed Younis Abdallah Yahia Ismail Mohammad Taher Source Type: research

Evaluation of short-term outcomes of neoadjuvant chemotherapy followed by radical cystectomy in muscle-invasive bladder cancer: a single Egyptian institution experience
CONCLUSIONS: Our results are further supporting the radiological and pathological benefits of NAC in MIBC, evidenced by tumor downstaging and pCR. The complication rate after RC is still considerable; hence, more larger studies are necessary to postulate a comprehensive risk assessment tool for patients who would get the maximum benefit from NAC, hoping to accomplish higher complete response rates with ultimately increased adoption of the bladder preservation strategies.PMID:37145329 | DOI:10.1186/s43046-023-00175-2 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 5, 2023 Category: Cancer & Oncology Authors: Ibrahim Abdelrahman Hatem Aboulkassem Abdallah Elazab Ahmed Younis Abdallah Yahia Ismail Mohammad Taher Source Type: research

Evaluation of short-term outcomes of neoadjuvant chemotherapy followed by radical cystectomy in muscle-invasive bladder cancer: a single Egyptian institution experience
CONCLUSIONS: Our results are further supporting the radiological and pathological benefits of NAC in MIBC, evidenced by tumor downstaging and pCR. The complication rate after RC is still considerable; hence, more larger studies are necessary to postulate a comprehensive risk assessment tool for patients who would get the maximum benefit from NAC, hoping to accomplish higher complete response rates with ultimately increased adoption of the bladder preservation strategies.PMID:37145329 | DOI:10.1186/s43046-023-00175-2 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 5, 2023 Category: Cancer & Oncology Authors: Ibrahim Abdelrahman Hatem Aboulkassem Abdallah Elazab Ahmed Younis Abdallah Yahia Ismail Mohammad Taher Source Type: research

Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research

Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research

Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research

Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research

Organ preservation strategy: new therapeutic alternative in rectal cancer
CONCLUSION: This nonoperative approach is currently widely studied in certain patients who have a complete response (clinical, endoscopic, and radiological). However, the selection of these patients is not simple and still complex.PMID:37093327 | PMC:PMC10123594 | DOI:10.1186/s43046-023-00169-0 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 24, 2023 Category: Cancer & Oncology Authors: F Safini B Amaoui S Semghouli N Aqodad Source Type: research

Organ preservation strategy: new therapeutic alternative in rectal cancer
CONCLUSION: This nonoperative approach is currently widely studied in certain patients who have a complete response (clinical, endoscopic, and radiological). However, the selection of these patients is not simple and still complex.PMID:37093327 | PMC:PMC10123594 | DOI:10.1186/s43046-023-00169-0 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 24, 2023 Category: Cancer & Oncology Authors: F Safini B Amaoui S Semghouli N Aqodad Source Type: research

Organ preservation strategy: new therapeutic alternative in rectal cancer
CONCLUSION: This nonoperative approach is currently widely studied in certain patients who have a complete response (clinical, endoscopic, and radiological). However, the selection of these patients is not simple and still complex.PMID:37093327 | PMC:PMC10123594 | DOI:10.1186/s43046-023-00169-0 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 24, 2023 Category: Cancer & Oncology Authors: F Safini B Amaoui S Semghouli N Aqodad Source Type: research

Organ preservation strategy: new therapeutic alternative in rectal cancer
CONCLUSION: This nonoperative approach is currently widely studied in certain patients who have a complete response (clinical, endoscopic, and radiological). However, the selection of these patients is not simple and still complex.PMID:37093327 | PMC:PMC10123594 | DOI:10.1186/s43046-023-00169-0 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 24, 2023 Category: Cancer & Oncology Authors: F Safini B Amaoui S Semghouli N Aqodad Source Type: research

Organ preservation strategy: new therapeutic alternative in rectal cancer
CONCLUSION: This nonoperative approach is currently widely studied in certain patients who have a complete response (clinical, endoscopic, and radiological). However, the selection of these patients is not simple and still complex.PMID:37093327 | PMC:PMC10123594 | DOI:10.1186/s43046-023-00169-0 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 24, 2023 Category: Cancer & Oncology Authors: F Safini B Amaoui S Semghouli N Aqodad Source Type: research