Patient characteristics and outcome of CD20-positive HIV-associated lymphoma: a single-center KwaZulu-Natal, South African hospital 12-year retrospective review
CONCLUSION: Although the clinical characteristics and laboratory findings are similar to other higher-income cohorts, there was a difference in gender and incidence of marrow involvement. The low incidence of marrow involvement has prompted more routine use of immunohistochemistry and flow cytometry in staging marrows of HAL locally. Further randomized studies are required for the establishment of locally validated, cost-effective treatment guidelines.PMID:35909189 | DOI:10.1186/s43046-022-00131-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 31, 2022 Category: Cancer & Oncology Authors: Nadine Rapiti Nada Abdelatif Anand Rapiti Mahomed-Yunus Moosa Source Type: research
Patient characteristics and outcome of CD20-positive HIV-associated lymphoma: a single-center KwaZulu-Natal, South African hospital 12-year retrospective review
CONCLUSION: Although the clinical characteristics and laboratory findings are similar to other higher-income cohorts, there was a difference in gender and incidence of marrow involvement. The low incidence of marrow involvement has prompted more routine use of immunohistochemistry and flow cytometry in staging marrows of HAL locally. Further randomized studies are required for the establishment of locally validated, cost-effective treatment guidelines.PMID:35909189 | DOI:10.1186/s43046-022-00131-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 31, 2022 Category: Cancer & Oncology Authors: Nadine Rapiti Nada Abdelatif Anand Rapiti Mahomed-Yunus Moosa Source Type: research
Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients
CONCLUSIONS: Genetic profiling using simple quantitative real-time polymerase chain reaction (qRT-PCR) protocols could be used to assess response to tamoxifen treatment in MBC patients. According to our data, a five-gene panel in the EGFR pathway (JAK1, COL1A1, GAB1, FN1 and MKNK1) could be used to categorize MBC patients into groups according to treatment response.PMID:35871690 | DOI:10.1186/s43046-022-00132-5 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 24, 2022 Category: Cancer & Oncology Authors: Ibrahim Malash Osman Mansour Rabab Gaafar Sabry Shaarawy Mona S Abdellateif Ola S Ahmed Abdel-Rahman N Zekri Abeer Bahnassy Source Type: research
Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients
CONCLUSIONS: Genetic profiling using simple quantitative real-time polymerase chain reaction (qRT-PCR) protocols could be used to assess response to tamoxifen treatment in MBC patients. According to our data, a five-gene panel in the EGFR pathway (JAK1, COL1A1, GAB1, FN1 and MKNK1) could be used to categorize MBC patients into groups according to treatment response.PMID:35871690 | DOI:10.1186/s43046-022-00132-5 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 24, 2022 Category: Cancer & Oncology Authors: Ibrahim Malash Osman Mansour Rabab Gaafar Sabry Shaarawy Mona S Abdellateif Ola S Ahmed Abdel-Rahman N Zekri Abeer Bahnassy Source Type: research
Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients
CONCLUSIONS: Genetic profiling using simple quantitative real-time polymerase chain reaction (qRT-PCR) protocols could be used to assess response to tamoxifen treatment in MBC patients. According to our data, a five-gene panel in the EGFR pathway (JAK1, COL1A1, GAB1, FN1 and MKNK1) could be used to categorize MBC patients into groups according to treatment response.PMID:35871690 | DOI:10.1186/s43046-022-00132-5 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 24, 2022 Category: Cancer & Oncology Authors: Ibrahim Malash Osman Mansour Rabab Gaafar Sabry Shaarawy Mona S Abdellateif Ola S Ahmed Abdel-Rahman N Zekri Abeer Bahnassy Source Type: research
Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients
CONCLUSIONS: Genetic profiling using simple quantitative real-time polymerase chain reaction (qRT-PCR) protocols could be used to assess response to tamoxifen treatment in MBC patients. According to our data, a five-gene panel in the EGFR pathway (JAK1, COL1A1, GAB1, FN1 and MKNK1) could be used to categorize MBC patients into groups according to treatment response.PMID:35871690 | DOI:10.1186/s43046-022-00132-5 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 24, 2022 Category: Cancer & Oncology Authors: Ibrahim Malash Osman Mansour Rabab Gaafar Sabry Shaarawy Mona S Abdellateif Ola S Ahmed Abdel-Rahman N Zekri Abeer Bahnassy Source Type: research
Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients
CONCLUSIONS: Genetic profiling using simple quantitative real-time polymerase chain reaction (qRT-PCR) protocols could be used to assess response to tamoxifen treatment in MBC patients. According to our data, a five-gene panel in the EGFR pathway (JAK1, COL1A1, GAB1, FN1 and MKNK1) could be used to categorize MBC patients into groups according to treatment response.PMID:35871690 | DOI:10.1186/s43046-022-00132-5 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 24, 2022 Category: Cancer & Oncology Authors: Ibrahim Malash Osman Mansour Rabab Gaafar Sabry Shaarawy Mona S Abdellateif Ola S Ahmed Abdel-Rahman N Zekri Abeer Bahnassy Source Type: research
Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients
CONCLUSIONS: Genetic profiling using simple quantitative real-time polymerase chain reaction (qRT-PCR) protocols could be used to assess response to tamoxifen treatment in MBC patients. According to our data, a five-gene panel in the EGFR pathway (JAK1, COL1A1, GAB1, FN1 and MKNK1) could be used to categorize MBC patients into groups according to treatment response.PMID:35871690 | DOI:10.1186/s43046-022-00132-5 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 24, 2022 Category: Cancer & Oncology Authors: Ibrahim Malash Osman Mansour Rabab Gaafar Sabry Shaarawy Mona S Abdellateif Ola S Ahmed Abdel-Rahman N Zekri Abeer Bahnassy Source Type: research
Prognostic significance of STAT3 gene expression in patients with glioblastoma tumors: a study from Western India
CONCLUSION: For GBM tumors, STAT3 up-regulation and presence of IDH mutations together predicts better survival. This reflects unique molecular etiology for GBM patients. Therefore, they would be useful in the future for targeted therapy and for clinicians they would be useful for better patient management. However, study on a larger sample size is required for validation.PMID:35844028 | DOI:10.1186/s43046-022-00133-4 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 17, 2022 Category: Cancer & Oncology Authors: Trupti Trivedi Kinjal Panchal Neha Bhalala Priti Trivedi Source Type: research
Prognostic significance of STAT3 gene expression in patients with glioblastoma tumors: a study from Western India
CONCLUSION: For GBM tumors, STAT3 up-regulation and presence of IDH mutations together predicts better survival. This reflects unique molecular etiology for GBM patients. Therefore, they would be useful in the future for targeted therapy and for clinicians they would be useful for better patient management. However, study on a larger sample size is required for validation.PMID:35844028 | DOI:10.1186/s43046-022-00133-4 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 17, 2022 Category: Cancer & Oncology Authors: Trupti Trivedi Kinjal Panchal Neha Bhalala Priti Trivedi Source Type: research
Prognostic significance of STAT3 gene expression in patients with glioblastoma tumors: a study from Western India
CONCLUSION: For GBM tumors, STAT3 up-regulation and presence of IDH mutations together predicts better survival. This reflects unique molecular etiology for GBM patients. Therefore, they would be useful in the future for targeted therapy and for clinicians they would be useful for better patient management. However, study on a larger sample size is required for validation.PMID:35844028 | DOI:10.1186/s43046-022-00133-4 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 17, 2022 Category: Cancer & Oncology Authors: Trupti Trivedi Kinjal Panchal Neha Bhalala Priti Trivedi Source Type: research
Prognostic significance of STAT3 gene expression in patients with glioblastoma tumors: a study from Western India
CONCLUSION: For GBM tumors, STAT3 up-regulation and presence of IDH mutations together predicts better survival. This reflects unique molecular etiology for GBM patients. Therefore, they would be useful in the future for targeted therapy and for clinicians they would be useful for better patient management. However, study on a larger sample size is required for validation.PMID:35844028 | DOI:10.1186/s43046-022-00133-4 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 17, 2022 Category: Cancer & Oncology Authors: Trupti Trivedi Kinjal Panchal Neha Bhalala Priti Trivedi Source Type: research
Prognostic significance of STAT3 gene expression in patients with glioblastoma tumors: a study from Western India
CONCLUSION: For GBM tumors, STAT3 up-regulation and presence of IDH mutations together predicts better survival. This reflects unique molecular etiology for GBM patients. Therefore, they would be useful in the future for targeted therapy and for clinicians they would be useful for better patient management. However, study on a larger sample size is required for validation.PMID:35844028 | DOI:10.1186/s43046-022-00133-4 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 17, 2022 Category: Cancer & Oncology Authors: Trupti Trivedi Kinjal Panchal Neha Bhalala Priti Trivedi Source Type: research
Prognostic significance of STAT3 gene expression in patients with glioblastoma tumors: a study from Western India
CONCLUSION: For GBM tumors, STAT3 up-regulation and presence of IDH mutations together predicts better survival. This reflects unique molecular etiology for GBM patients. Therefore, they would be useful in the future for targeted therapy and for clinicians they would be useful for better patient management. However, study on a larger sample size is required for validation.PMID:35844028 | DOI:10.1186/s43046-022-00133-4 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 17, 2022 Category: Cancer & Oncology Authors: Trupti Trivedi Kinjal Panchal Neha Bhalala Priti Trivedi Source Type: research
Tumor response to radiotherapy and expression of epidermal growth factor receptor mutation and echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase rearrangement in patients with non-small cell lung cancer
CONCLUSION: Patients with overexpression of EGFR mutations are more radiosensitive during the early treatment phase, and EML4-ALK mutations were less radiosensitive regardless of phases.PMID:35811311 | DOI:10.1186/s43046-022-00130-7 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - July 10, 2022 Category: Cancer & Oncology Authors: Nadeem M S Nagi Yasir A M Khair Khamis H Bakari Mohamed N Nagi Fabian P Mghanga Source Type: research
