Neuroendovascular Cerebral Sinus Stenting in Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a rare, ill-understood disease of significant morbidity. Because the pathophysiology is poorly understood, treatment protocols are not uniform and are directed towards alleviating the most common symptoms: headache and visual loss. In this review, we analyze 25 case series, all of which included IIH patients (n = 408) who were treated with placement of a venous sinus stent. Among 342 patients who had headache, 240 patients (70.2%) had improvement or resolution of headache after the stent insertion. Of the 217 patients documented to have visual problems, visual acuity was improv...
Source: Interventional Neurology - June 4, 2019 Category: Neurology Source Type: research
The Effects of Cerebral Vasospasm on Cerebral Blood Flow and the Effects of Induced Hypertension: A Mathematical Modelling Study
Conclusion: Under vasospastic condition, cerebral blood flow varies considerably. Hypertension can raise the blood flow, but it is unable to restore cerebral blood flow to baseline.Intervent Neurol 2019;8:152 –163 (Source: Interventional Neurology)
Source: Interventional Neurology - April 3, 2019 Category: Neurology Source Type: research
Body Mass Index and Clinical Outcomes in Large Vessel Occlusion Acute Ischemic Stroke after Endovascular Therapy
Conclusion: In patients treated with mechanical thrombectomy, BMI is not associated with outcomes. However, patients who are overweight or obese have more comorbidities and a higher stroke risk and, thus, should strive for a normal weight.Intervent Neurol 2019;8:144 –151 (Source: Interventional Neurology)
Source: Interventional Neurology - March 31, 2019 Category: Neurology Source Type: research
Impact of MRI Selection on Triage of Endovascular Therapy in Acute Ischemic Stroke: The MRI in Acute Management of Ischemic Stroke (MIAMIS) Registry
Conclusions: Multimodality MRI screening for AIS symptoms for ET is feasible. Optimizing each center ’s protocol and the utilization of MRI with DWI only may be a time-saving alternative.Intervent Neurol 2019;8:135 –143 (Source: Interventional Neurology)
Source: Interventional Neurology - March 16, 2019 Category: Neurology Source Type: research
Prospective Endovascular Treatment in Acute Ischemic Stroke Evaluating Non-Contrast Head CT versus CT Perfusion (PLEASE No CTP)
Conclusions: CTP penumbra did not identify patients who would benefit from endovascular treatment when patients were selected with non-contrast CT ASPECTS ≥7. There is no correlation of CTP penumbra with good outcomes or mortality. Larger prospective trials are warranted to justify the use of CTP within 6 h of symptom onset.Intervent Neurol 2019;8:116 –122 (Source: Interventional Neurology)
Source: Interventional Neurology - March 7, 2019 Category: Neurology Source Type: research
Platelet Function Testing in Neurovascular Procedures: Tool or Gimmick?
Conclusion: PFT appears to identify patients with clopidogrel resistance prior to NVS procedures. When non-responders are converted to alternative platelet inhibitors, neurological outcomes and thromboembolic complication rates may improve. Consequently, this study provides preliminary evidence that PFT may be a useful clinical tool to enhance procedural safety and improve clinical outcomes in NVS procedures.Intervent Neurol 2019;8:123 –134 (Source: Interventional Neurology)
Source: Interventional Neurology - March 7, 2019 Category: Neurology Source Type: research
Head or Neck First? Speed and Rates of Reperfusion in Thrombectomy for Tandem Large Vessel Occlusion Strokes
Conclusions: The upfront approach of the intracranial lesion in patients with tandem large vessel occlusion strokes leads to similar reperfusion rates but faster reperfusion as compared to initial cervical revascularization followed by mechanical thrombectomy. Controlled studies are warranted.Intervent Neurol 2019;8:92 –100 (Source: Interventional Neurology)
Source: Interventional Neurology - February 15, 2019 Category: Neurology Source Type: research
Endovascular Reconstruction of Intracranial Aneurysms with the Pipeline Embolization Device in Pediatric Patients: A Single-Center Series
Conclusion: While further investigation is needed, the evidence presented here supports the conclusion that the PED can be an effective and viable treatment strategy in the pediatric population.Intervent Neurol 2019;8:101 –108 (Source: Interventional Neurology)
Source: Interventional Neurology - February 15, 2019 Category: Neurology Source Type: research
Association of Menopausal Age with Unruptured Intracranial Aneurysm Morphology
Conclusions: A trend to increased UIA maximal diameter and neck size was seen in the POM group compared to the PRM group. The PRM group had a significantly higher number of UIA lobes. Larger prospective trials are needed to confirm these findings.Intervent Neurol 2019;8:109 –115 (Source: Interventional Neurology)
Source: Interventional Neurology - February 15, 2019 Category: Neurology Source Type: research
Safety and Efficacy of the Pipeline Embolization Device Use in the Outside Circle of Willis Located Intracranial Aneurysms: A Single-Center Experience
Conclusion: The use of PED to treat aneurysms located outside the circle of Willis is feasible and effective. Our novel antiplatelet protocol did not require platelet function assay testing and did not lead to a higher rate of thrombo-embolic events compared to what has been previously reported.Intervent Neurol 2019;8:83 –91 (Source: Interventional Neurology)
Source: Interventional Neurology - January 16, 2019 Category: Neurology Source Type: research
Real-World Impact of Retrievable Stents for Acute Ischemic Stroke on Disability Utilizing the National Inpatient Sample
Conclusions: The FDA approval of RS technology after 2012 was associated with decreased in-hospital mortality when compared with the 3-year interval prior. These findings provide an indication that the RCT data on the efficacy of RS technology are translating into improved real-world outcomes.Intervent Neurol 2019;8:60 –68 (Source: Interventional Neurology)
Source: Interventional Neurology - December 13, 2018 Category: Neurology Source Type: research
Mandatory Neuroendovascular Evolution: Meeting the New Demands
Background: Traditionally, patients undergoing acute ischemic strokes were candidates for mechanical thrombectomy if they were within the 6-h window from onset of symptoms. This timeframe would exclude many patient populations, such as wake-up strokes. However, the most recent clinical trials, DAWN and DEFUSE3, have expanded the window of endovascular treatment for acute ischemic stroke patients to within 24 h from symptom onset. This expanded window increases the number of potential candidates for endovascular intervention for emergent large vessel occlusions and raises the question of how to efficiently screen and triage...
Source: Interventional Neurology - December 13, 2018 Category: Neurology Source Type: research
