Immunological processes of enhancers and suppressors of long non-coding RNAs associated with brain tumors and inflammation
Int Rev Immunol. 2023 Nov 17:1-19. doi: 10.1080/08830185.2023.2280581. Online ahead of print.ABSTRACTImmunological processes, such as inflammation, can both cause tumor suppression and cancer progression. Moreover, deregulated levels of long non-coding RNA (lncRNA) expression in the brain may cause inflammation and lead to the growth of tumors. Like other biological processes, the immune system's role in cancer is complicated, varies, and can help or hurt the cancer's maintenance. According to research, inflammation and brain cancer are correlated via several signaling pathways. A variety of lncRNAs have recently been reve...
Source: International Reviews of Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Hossein Tahmasebi Dehkordi Fatemeh Khaledi Sorayya Ghasemi Source Type: research

RNA methylation: A potential therapeutic target in autoimmune disease
Int Rev Immunol. 2023 Nov 17:1-18. doi: 10.1080/08830185.2023.2280544. Online ahead of print.ABSTRACTAutoimmune diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and inflammatory bowel disease (IBD) are caused by the body's immune response to autoantigens. The pathogenesis of autoimmune diseases is unclear. Numerous studies have demonstrated that RNA methylation plays a key role in disease progression, which is essential for post-transcriptional regulation and has gradually become a broad regulatory mechanism that controls gene expression in various physiological processes, including RNA nucle...
Source: International Reviews of Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Lele Li Xiaoping Xia Tian Yang Yuchao Sun Xueke Liu Wei Xu Mei Lu Dawei Cui Yingping Wu Source Type: research

Immunological processes of enhancers and suppressors of long non-coding RNAs associated with brain tumors and inflammation
Int Rev Immunol. 2023 Nov 17:1-19. doi: 10.1080/08830185.2023.2280581. Online ahead of print.ABSTRACTImmunological processes, such as inflammation, can both cause tumor suppression and cancer progression. Moreover, deregulated levels of long non-coding RNA (lncRNA) expression in the brain may cause inflammation and lead to the growth of tumors. Like other biological processes, the immune system's role in cancer is complicated, varies, and can help or hurt the cancer's maintenance. According to research, inflammation and brain cancer are correlated via several signaling pathways. A variety of lncRNAs have recently been reve...
Source: International Reviews of Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Hossein Tahmasebi Dehkordi Fatemeh Khaledi Sorayya Ghasemi Source Type: research