Quantification of Aging-Related Decreases in Sensory Innervation of the Bladder Trigone in Rats
CONCLUSION: The structural and functional integrity of the sensory web in the trigonum of rats is negatively affected by the aging process, potentially leading to impaired communication between the bladder urothelium the CNS. Consequently, these perturbations in the sensory system may contribute to the pathogenesis or exacerbation LUTS.PMID:38461855 | DOI:10.5213/inj.2346220.110 (Source: International Neurourology Journal)
Source: International Neurourology Journal - March 10, 2024 Category: Urology & Nephrology Authors: Mathijs M de Rijk Sa ša Peter Amanda Wolf-Johnston John Heesakkers Gommert A van Koeveringe Lori A Birder Source Type: research

Adreno-Muscarinic Synergy of Contractile Responses From Human Hyperplastic Prostate
CONCLUSION: These experiments show that adreno-muscarinic contractile synergy is a feature of human hyperplastic prostate tissue. This has implications for the use of a combination therapy of α-blockers and anti-muscarinic agent to relieve secondary symptoms associated with benign prostatic hyperplasia, at least in men who can tolerate antimuscarinics without a risk of retention.PMID:38461856 | DOI:10.5213/inj.2346144.122 (Source: International Neurourology Journal)
Source: International Neurourology Journal - March 10, 2024 Category: Urology & Nephrology Authors: Ben T Blake-James Basu Chakrabarty Christopher H Fry Source Type: research

Application of the Sleep C.A.L.M. Tool for Assessing Nocturia in a Large Nationally Representative Cohort
CONCLUSION: Sleep C.A.L.M. burden is associated with increased odds of nocturia in a dose-dependent fashion, and potentially a relevant means by which to organize the underlying etiologies for nocturia among community-dwelling adults.PMID:38461857 | DOI:10.5213/inj.2346258.129 (Source: International Neurourology Journal)
Source: International Neurourology Journal - March 10, 2024 Category: Urology & Nephrology Authors: Joseph U Boroda Benjamin De Leon Lakshay Khosla Muchi D Chobufo Syed N Rahman Jason M Lazar Jeffrey P Weiss Thomas F Monaghan Source Type: research

Corrigendum: Transfer Learning for Effective Urolithiasis Detection
Int Neurourol J. 2024 Feb;28(Suppl 1):62. doi: 10.5213/inj.2423055.erratum. Epub 2024 Feb 29.NO ABSTRACTPMID:38461858 | DOI:10.5213/inj.2423055.erratum (Source: International Neurourology Journal)
Source: International Neurourology Journal - March 10, 2024 Category: Urology & Nephrology Authors: Hyoung-Sun Choi Jae-Seoung Kim Taeg-Keun Whangbo Khae-Hawn Kim Source Type: research

From Code to Cure: Unleashing the Power of Generative Artificial Intelligence in Medicine
Int Neurourol J. 2023 Dec;27(4):225-226. doi: 10.5213/inj.2323edi06. Epub 2023 Dec 31.NO ABSTRACTPMID:38171321 | PMC:PMC10762374 | DOI:10.5213/inj.2323edi06 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Young Sam Cho Source Type: research

The Current State of Artificial Intelligence Application in Urology
Int Neurourol J. 2023 Dec;27(4):227-233. doi: 10.5213/inj.2346336.168. Epub 2023 Dec 31.ABSTRACTArtificial intelligence (AI) is being used in many areas of healthcare, including disease diagnosis and personalized treatment and rehabilitation management. Medical AI research and development has primarily focused on diagnosis, prediction, treatment, and management as an aid to patient care. AI is being utilized primarily in the areas of personal healthcare and diagnostic imaging. In the field of urology, significant investments are being made in the development of urination monitoring systems in the field of personal healthca...
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Eui-Sun Kim Sung-Jong Eun Seunghyun Youn Source Type: research

Differential Gene Expression in the Penile Cavernosum of Streptozotocin-Induced Diabetic Rats
CONCLUSION: This study broadens the scope of candidate genes that may be relevant to the pathophysiology of diabetic ED. In particular, their enhancement or inhibition could represent a novel treatment for diabetic ED.PMID:38171323 | PMC:PMC10762368 | DOI:10.5213/inj.2346074.037 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Jae Heon Kim Hee Jo Yang Suyeon Park Hong Jun Lee Yun Seob Song Source Type: research

Adenosine A2A Receptor Agonist, Polydeoxyribonucleotide Treatment Improves Locomotor Function and Thermal Hyperalgesia Following Neuropathic Pain in Rats
CONCLUSION: PDRN has shown potential to be used as an effective treatment for neuropathic pain.PMID:38171324 | PMC:PMC10762369 | DOI:10.5213/inj.2326154.127 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Ye Chan Joo Jun Young Chung Soon Oh Kwon Jin Hee Han Source Type: research

The Risk of Stress Urinary Incontinence After Hysterectomy for Uterine Fibroids
CONCLUSION: Prior abdominal hysterectomy without adnexal surgery was associated with an increased incidence of subsequent anti-urinary incontinence surgery.PMID:38171325 | PMC:PMC10762370 | DOI:10.5213/inj.2346192.096 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Jin-Sung Yuk In-Chang Cho Jun Ho Lee Source Type: research

Intravesical Electrical Stimulation Improves Abnormal Prefrontal Brain Activity in Patients With Underactive Bladder: A Possible Central Mechanism
CONCLUSION: The possible central mechanism of IVES treatment for neurogenic UAB is that IVES reactivates the right DLPFC and right frontal pole.PMID:38171326 | PMC:PMC10762371 | DOI:10.5213/inj.2346232.116 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Han Deng Limin Liao Juan Wu Li Wan Source Type: research

Decreased Angiopoietin Expression in Underactive Bladder Induced by Long-term Bladder Outlet Obstruction
CONCLUSION: In a rat model of underactive bladder caused by surgical BOO, reduced angiopoietin expression was demonstrated. This observation might underlie visceral ischemia and fibrosis associated with the procedure. The findings of this study might offer an improved understanding of the disease processes underlying BOO and facilitate selection of the appropriate time to repair the organ in this condition.PMID:38171327 | PMC:PMC10762367 | DOI:10.5213/inj.2346296.148 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Jae Heon Kim Hee Jo Yang Hong Jun Lee Yun Seob Song Source Type: research

Artificial Intelligence-Based Patient Monitoring System for Medical Support
CONCLUSION: In this study, we developed a urination disease monitoring system aimed at predicting and managing risks for patients with urination issues. The system is designed to support the entire care cycle of a patient by leveraging AI technology that processes various image and signal data. We anticipate that this system will evolve into digital treatment products, ultimately providing therapeutic benefits to patients.PMID:38171328 | PMC:PMC10762372 | DOI:10.5213/inj.2346338.169 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Eui-Sun Kim Sung-Jong Eun Khae-Hawn Kim Source Type: research

From Code to Cure: Unleashing the Power of Generative Artificial Intelligence in Medicine
Int Neurourol J. 2023 Dec;27(4):225-226. doi: 10.5213/inj.2323edi06. Epub 2023 Dec 31.NO ABSTRACTPMID:38171321 | PMC:PMC10762374 | DOI:10.5213/inj.2323edi06 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Young Sam Cho Source Type: research

The Current State of Artificial Intelligence Application in Urology
Int Neurourol J. 2023 Dec;27(4):227-233. doi: 10.5213/inj.2346336.168. Epub 2023 Dec 31.ABSTRACTArtificial intelligence (AI) is being used in many areas of healthcare, including disease diagnosis and personalized treatment and rehabilitation management. Medical AI research and development has primarily focused on diagnosis, prediction, treatment, and management as an aid to patient care. AI is being utilized primarily in the areas of personal healthcare and diagnostic imaging. In the field of urology, significant investments are being made in the development of urination monitoring systems in the field of personal healthca...
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Eui-Sun Kim Sung-Jong Eun Seunghyun Youn Source Type: research

Differential Gene Expression in the Penile Cavernosum of Streptozotocin-Induced Diabetic Rats
CONCLUSION: This study broadens the scope of candidate genes that may be relevant to the pathophysiology of diabetic ED. In particular, their enhancement or inhibition could represent a novel treatment for diabetic ED.PMID:38171323 | PMC:PMC10762368 | DOI:10.5213/inj.2346074.037 (Source: International Neurourology Journal)
Source: International Neurourology Journal - January 3, 2024 Category: Urology & Nephrology Authors: Jae Heon Kim Hee Jo Yang Suyeon Park Hong Jun Lee Yun Seob Song Source Type: research