Periodic Rotation versus Continuous Application of Same Nasal Interface for Non-invasive Respiratory Support in Preterm Neonates: A Systematic Review and Meta-analysis
ConclusionsAmong preterm infants receiving non-invasive respiratory support, periodically rotating a nasal mask with short binasal prongs may not be superior to the continuous application of nasal masks. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 15, 2023 Category: Pediatrics Source Type: research

Childhood Vasculitis
AbstractOf the primary vasculitis pediatricians are familiar with, Kawasaki disease and IgA vasculitis are the most common. The other large, medium and small vessel vasculitis are seldom seen in practice. Though rare, early diagnosis and appropriate management is critical for the best outcome. Primary vasculitis in the pediatric age group have several differential diagnoses which range from infections to monogenic causes such as deficiency of Adenosine Deaminase -2. Each child, therefore, needs a careful systematic approach. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 15, 2023 Category: Pediatrics Source Type: research

Shortened Treatment Regimens for Drug Sensitive TB
This article reviews the current evidence and the guidelines pertaining to the shortened, intensive regimens for dr ug-sensitive tuberculosis. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 15, 2023 Category: Pediatrics Source Type: research

Back-Referral of Convalescing Neonates: Challenges and Strategies in India
ConclusionsEstablishing efficient two-way communication between tertiary centres and district SNCUs, provision of essential facilities at SNCUs, and ensuring a seamless continuum of care are pivotal for successful back-referral of convalescent neonates. Addressing these factors can contribute to improving the back-referral process, level 3 bed availability at the tertiary centres and neonatal health outcomes. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 15, 2023 Category: Pediatrics Source Type: research

Serum Inflammatory Markers in Children with Severe Acute Malnutrition with Systemic Infections: A Case –Control Study
This study suggests that SAM children had some ability to mount an inflammatory response during a systemic infection, but it was weaker compared to nutritionally normal children with a systemic infection. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 15, 2023 Category: Pediatrics Source Type: research

Burden of Pediatric Scrub Typhus at a Tertiary Care Hospital: Clinical, Biochemical, Complications and Predictors of Mortality and Morbidity
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 15, 2023 Category: Pediatrics Source Type: research

Status Dystonicus: An Atypical  Presentation of Subacute Sclerosing Panencephalitis
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 15, 2023 Category: Pediatrics Source Type: research

Tuberculosis Preventive Treatment
AbstractSome individuals exposed toMycobacterium tuberculosis develop a latent infection and remain at a lifelong risk of developing tuberculosis (TB) disease, a state called as TB infection (TBI). TB preventive treatment (TPT) aims to treat TBI and prevent progression to active TB in an exposed or infected person. Currently, it is not possible to confirm TBI microbiologically, but can be identified indirectly by means of immune-based tests [Tuberculin skin test (TST), interferon-gamma release assays (IGRAs)]. It is crucial to rule out active TB before initiating TPT. TPT regimens have evolved with time. The most widely us...
Source: Indian Journal of Pediatrics - December 14, 2023 Category: Pediatrics Source Type: research

Bacteriological Profile and Antibiogram of Ventilator Associated Pneumonia
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 14, 2023 Category: Pediatrics Source Type: research

Correlation of Serum Calprotectin with SOFA Score in Pediatric Sepsis – A Cross-sectional Pilot Study
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 14, 2023 Category: Pediatrics Source Type: research

Outbreak of Ralstonia pickettii Blood Stream Infection in Pediatric Intensive Care Unit
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 14, 2023 Category: Pediatrics Source Type: research

Metabolic Evaluation in Children aged 3 months to 2 years with Global Developmental Delay
ConclusionsAmong children with GDD of unclear etiology, metabolic errors constitute a small proportion of etiology. In this group early metabolic tests could identify potentially treatable conditions. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 12, 2023 Category: Pediatrics Source Type: research

The Intricate Dance of Infections and Autoimmunity: An Interesting Paradox
AbstractBesides genetic susceptibility, infections due to viruses, bacteria and protozoa have been implicated in the development of autoimmune diseases (AD). AD can be triggered in a genetically susceptible individual by infections that disrupt immunological tolerance towards self-antigens. Pathogens can initiate autoimmunity by way of molecular mimicry, bystander activation, epitope spreading or persistent infection with polyclonal activation. This review covers two main topics: (i) the mechanisms by which an infectious agent can trigger or worsen autoimmunity; and (ii) the correlation between specific infectious agents a...
Source: Indian Journal of Pediatrics - December 12, 2023 Category: Pediatrics Source Type: research

Rapid Steroid Withdrawal Unveiling Tender Nodules: A Pediatric Panniculitis Puzzle and its Management
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 12, 2023 Category: Pediatrics Source Type: research

Drug Resistant Epilepsy (DRE) Secondary to 3-Hydroxy Acyl-CoA Dehydrogenase Deficiency (HADH) in Siblings
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 12, 2023 Category: Pediatrics Source Type: research