Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Jul 22;71:101548. doi: 10.1016/j.ghir.2023.101548. Online ahead of print.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be con...
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Jul 22;71:101548. doi: 10.1016/j.ghir.2023.101548. Online ahead of print.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be con...
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Jul 22;71:101548. doi: 10.1016/j.ghir.2023.101548. Online ahead of print.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be con...
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Jul 22;71:101548. doi: 10.1016/j.ghir.2023.101548. Online ahead of print.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be con...
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Jul 22;71:101548. doi: 10.1016/j.ghir.2023.101548. Online ahead of print.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be con...
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Jul 22;71:101548. doi: 10.1016/j.ghir.2023.101548. Online ahead of print.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be con...
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Prevalence of refractoriness when testing growth hormone levels in children
CONCLUSIONS: Many children with short stature were refractory at testing; among them we found few clinical characteristics. Refractoriness might be influenced by some differences in procedure, but needs to be considered when evaluating GH response in children.PMID:37562165 | DOI:10.1016/j.ghir.2023.101549 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - August 10, 2023 Category: Endocrinology Authors: Camilla Borghammar Victoria Boije Charlotte Becker Bengt Lindberg Maria Elfving Source Type: research
Prevalence of refractoriness when testing growth hormone levels in children
CONCLUSIONS: Many children with short stature were refractory at testing; among them we found few clinical characteristics. Refractoriness might be influenced by some differences in procedure, but needs to be considered when evaluating GH response in children.PMID:37562165 | DOI:10.1016/j.ghir.2023.101549 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - August 10, 2023 Category: Endocrinology Authors: Camilla Borghammar Victoria Boije Charlotte Becker Bengt Lindberg Maria Elfving Source Type: research
Prevalence of refractoriness when testing growth hormone levels in children
CONCLUSIONS: Many children with short stature were refractory at testing; among them we found few clinical characteristics. Refractoriness might be influenced by some differences in procedure, but needs to be considered when evaluating GH response in children.PMID:37562165 | DOI:10.1016/j.ghir.2023.101549 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - August 10, 2023 Category: Endocrinology Authors: Camilla Borghammar Victoria Boije Charlotte Becker Bengt Lindberg Maria Elfving Source Type: research
Prevalence of refractoriness when testing growth hormone levels in children
CONCLUSIONS: Many children with short stature were refractory at testing; among them we found few clinical characteristics. Refractoriness might be influenced by some differences in procedure, but needs to be considered when evaluating GH response in children.PMID:37562165 | DOI:10.1016/j.ghir.2023.101549 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - August 10, 2023 Category: Endocrinology Authors: Camilla Borghammar Victoria Boije Charlotte Becker Bengt Lindberg Maria Elfving Source Type: research
Prevalence of refractoriness when testing growth hormone levels in children
CONCLUSIONS: Many children with short stature were refractory at testing; among them we found few clinical characteristics. Refractoriness might be influenced by some differences in procedure, but needs to be considered when evaluating GH response in children.PMID:37562165 | DOI:10.1016/j.ghir.2023.101549 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - August 10, 2023 Category: Endocrinology Authors: Camilla Borghammar Victoria Boije Charlotte Becker Bengt Lindberg Maria Elfving Source Type: research
Prevalence of refractoriness when testing growth hormone levels in children
CONCLUSIONS: Many children with short stature were refractory at testing; among them we found few clinical characteristics. Refractoriness might be influenced by some differences in procedure, but needs to be considered when evaluating GH response in children.PMID:37562165 | DOI:10.1016/j.ghir.2023.101549 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - August 10, 2023 Category: Endocrinology Authors: Camilla Borghammar Victoria Boije Charlotte Becker Bengt Lindberg Maria Elfving Source Type: research
