Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research
Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research
Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research
Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research
Comparison of hyperoxia or normoxia resolution of intermittent hypoxia and intermittent hyperoxia episodes on liver histopathology, IGF-1, IGFBP-3, and GHBP in neonatal rats
CONCLUSIONS: Exposure to IH or intermittent hyperoxia during the first few weeks of life regardless of resolution in RA or hyperoxia is detrimental to the immature liver. These findings may suggest that interventions to prevent frequent fluctuations in oxygen saturation during early neonatal life remain a high priority.PMID:37708588 | DOI:10.1016/j.ghir.2023.101559 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 14, 2023 Category: Endocrinology Authors: Charles L Cai Matthew Marcelino Jacob V Aranda Kay D Beharry Source Type: research
Growth hormone therapy for children with Duchenne muscular dystrophy and glucocorticoid induced short stature
CONCLUSIONS: rhGH appears to be safe and efficient in promoting growth of patients with glucocorticoid induced growth failure in DMD.PMID:37683457 | DOI:10.1016/j.ghir.2023.101558 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 8, 2023 Category: Endocrinology Authors: Eran Lavi Amitay Cohen Abdulsalam Abu Libdeh Reuven Tsabari David Zangen Talya Dor Source Type: research
Growth hormone therapy for children with Duchenne muscular dystrophy and glucocorticoid induced short stature
CONCLUSIONS: rhGH appears to be safe and efficient in promoting growth of patients with glucocorticoid induced growth failure in DMD.PMID:37683457 | DOI:10.1016/j.ghir.2023.101558 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 8, 2023 Category: Endocrinology Authors: Eran Lavi Amitay Cohen Abdulsalam Abu Libdeh Reuven Tsabari David Zangen Talya Dor Source Type: research
Growth hormone therapy for children with Duchenne muscular dystrophy and glucocorticoid induced short stature
CONCLUSIONS: rhGH appears to be safe and efficient in promoting growth of patients with glucocorticoid induced growth failure in DMD.PMID:37683457 | DOI:10.1016/j.ghir.2023.101558 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 8, 2023 Category: Endocrinology Authors: Eran Lavi Amitay Cohen Abdulsalam Abu Libdeh Reuven Tsabari David Zangen Talya Dor Source Type: research
Growth hormone therapy for children with Duchenne muscular dystrophy and glucocorticoid induced short stature
CONCLUSIONS: rhGH appears to be safe and efficient in promoting growth of patients with glucocorticoid induced growth failure in DMD.PMID:37683457 | DOI:10.1016/j.ghir.2023.101558 (Source: Growth Hormone and IGF Research)
Source: Growth Hormone and IGF Research - September 8, 2023 Category: Endocrinology Authors: Eran Lavi Amitay Cohen Abdulsalam Abu Libdeh Reuven Tsabari David Zangen Talya Dor Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein(a)-impact on atherosclerotic cardiovascular disease
Growth Horm IGF Res. 2023 Aug;71:101548. doi: 10.1016/j.ghir.2023.101548. Epub 2023 Jul 22.ABSTRACTInsulin like growth factor I (IGFI) secreted by the liver upon stimulation by pituitary growth hormone (GH) acts as the most important growth stimulating hormone in children. The present review presents evidence that among its additional metabolic effects, IGF-I suppresses the synthesis of lipoprotein(a) [Lp(a)], an independent risk factor for atherosclerotic cardiovascular disease. In view of this property, it is suggested that the addition of IGF-I to the armamentarium of hyperlipoproteinemia treatment should be considered....
Source: Growth Hormone and IGF Research - August 20, 2023 Category: Endocrinology Authors: Zvi Laron Haim Werner Source Type: research
