Effect of SGLT2 inhibitors versus DPP4 inhibitors on major and non-major osteoporotic fracture risks among general and high-risk type 2 diabetes patients: A nationwide retrospective cohort study
CONCLUSION: - This study adds supporting real-world evidence for SGLT2is-associated bone safety for a wide range of fractures, which promotes the rational use of SGLT2is in routine care and highlights the importance of the close monitoring of patients with high fracture risks to maximize treatment benefits while reducing undesirable effects.PMID:37451539 | DOI:10.1016/j.diabet.2023.101465 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - July 14, 2023 Category: Endocrinology Authors: Zi-Yang Peng Yao-Tseng Wang Chin-Sung Chang Chih-Hsing Wu Huang-Tz Ou Source Type: research

Effect of SGLT2 inhibitors versus DPP4 inhibitors on major and non-major osteoporotic fracture risks among general and high-risk type 2 diabetes patients: A nationwide retrospective cohort study
CONCLUSION: - This study adds supporting real-world evidence for SGLT2is-associated bone safety for a wide range of fractures, which promotes the rational use of SGLT2is in routine care and highlights the importance of the close monitoring of patients with high fracture risks to maximize treatment benefits while reducing undesirable effects.PMID:37451539 | DOI:10.1016/j.diabet.2023.101465 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - July 14, 2023 Category: Endocrinology Authors: Zi-Yang Peng Yao-Tseng Wang Chin-Sung Chang Chih-Hsing Wu Huang-Tz Ou Source Type: research

Effect of SGLT2 inhibitors versus DPP4 inhibitors on major and non-major osteoporotic fracture risks among general and high-risk type 2 diabetes patients: A nationwide retrospective cohort study
CONCLUSION: - This study adds supporting real-world evidence for SGLT2is-associated bone safety for a wide range of fractures, which promotes the rational use of SGLT2is in routine care and highlights the importance of the close monitoring of patients with high fracture risks to maximize treatment benefits while reducing undesirable effects.PMID:37451539 | DOI:10.1016/j.diabet.2023.101465 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - July 14, 2023 Category: Endocrinology Authors: Zi-Yang Peng Yao-Tseng Wang Chin-Sung Chang Chih-Hsing Wu Huang-Tz Ou Source Type: research

Effect of SGLT2 inhibitors versus DPP4 inhibitors on major and non-major osteoporotic fracture risks among general and high-risk type 2 diabetes patients: A nationwide retrospective cohort study
CONCLUSION: - This study adds supporting real-world evidence for SGLT2is-associated bone safety for a wide range of fractures, which promotes the rational use of SGLT2is in routine care and highlights the importance of the close monitoring of patients with high fracture risks to maximize treatment benefits while reducing undesirable effects.PMID:37451539 | DOI:10.1016/j.diabet.2023.101465 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - July 14, 2023 Category: Endocrinology Authors: Zi-Yang Peng Yao-Tseng Wang Chin-Sung Chang Chih-Hsing Wu Huang-Tz Ou Source Type: research

Effect of SGLT2 inhibitors versus DPP4 inhibitors on major and non-major osteoporotic fracture risks among general and high-risk type 2 diabetes patients: A nationwide retrospective cohort study
CONCLUSION: - This study adds supporting real-world evidence for SGLT2is-associated bone safety for a wide range of fractures, which promotes the rational use of SGLT2is in routine care and highlights the importance of the close monitoring of patients with high fracture risks to maximize treatment benefits while reducing undesirable effects.PMID:37451539 | DOI:10.1016/j.diabet.2023.101465 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - July 14, 2023 Category: Endocrinology Authors: Zi-Yang Peng Yao-Tseng Wang Chin-Sung Chang Chih-Hsing Wu Huang-Tz Ou Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research

Treatment of women with mild gestational diabetes mellitus decreases the risk of adverse perinatal outcomes
CONCLUSION: The diagnosis of GDM using the two-step OGTT fails to identify subgroups of women with mild hyperglycemia that would benefit from treatment to lower the risk for adverse maternal and neonatal outcomes. Treatment of women with mild hyperglycemia decreased the risk of LGA and birthweight >4000 g by 3-fold.PMID:37336281 | DOI:10.1016/j.diabet.2023.101458 (Source: Diabetes and Metabolism)
Source: Diabetes and Metabolism - June 19, 2023 Category: Endocrinology Authors: Fanny Goyette Bi Lan Wo Marie-H élène Iglesias Evelyne Rey Ariane Godbout Source Type: research