Severe Candida sepsis in a 28-year-old female patient with initial diagnosis of diabetes mellitus and marked hyperosmolar coma
We report on a 28-year-old female patient who had no history of diseases and who was brought to our intensive care unit in a comatose state by the ambulance service. The clinical picture corresponded to sepsis with a massively increased blood sugar concentration (> 2000 mg/dl) as well as a pronounced skin mycosis in the groin region of the very obese patient (body mass index [BMI]: 33.7 kg/m2) in the physical examination. The treatment of sepsis was initially supplemented by a calculated antifungal treatment. The blood culture diagnosis confirmed the presence of Candida albicans and Candida glabrata. Despite adequate an...
Source: Der Anaesthesist - November 24, 2021 Category: Anesthesiology Authors: S Niel R Douwa S G Sakka Source Type: research
Severe Candida sepsis in a 28-year-old female patient with initial diagnosis of diabetes mellitus and marked hyperosmolar coma
We report on a 28-year-old female patient who had no history of diseases and who was brought to our intensive care unit in a comatose state by the ambulance service. The clinical picture corresponded to sepsis with a massively increased blood sugar concentration (> 2000 mg/dl) as well as a pronounced skin mycosis in the groin region of the very obese patient (body mass index [BMI]: 33.7 kg/m2) in the physical examination. The treatment of sepsis was initially supplemented by a calculated antifungal treatment. The blood culture diagnosis confirmed the presence of Candida albicans and Candida glabrata. Despite adequate an...
Source: Der Anaesthesist - November 24, 2021 Category: Anesthesiology Authors: S Niel R Douwa S G Sakka Source Type: research
Development of a giant bulla under spontaneous breathing by self-inflicted lung injury in a patient with COVID-19 pneumonia
Anaesthesist. 2021 Nov 22:1-4. doi: 10.1007/s00101-021-01072-w. Online ahead of print.ABSTRACTThe outbreak of SARS-CoV‑2 and the associated COVID-19 pandemic pose major challenges to healthcare systems worldwide. New data on diagnosis, clinical presentation and treatment of the disease are published on a daily basis. This case report describes the fatal course of severe COVID-19 pneumonia in an 81-year-old patient with no previous pulmonary disease who developed a giant bulla during non-invasive high-flow oxygen therapy. Virus-induced diffuse destruction of alveolar tissue or patient self-inflicted lung injury (P-SILI) a...
Source: Der Anaesthesist - November 23, 2021 Category: Anesthesiology Authors: Nicholas Moellhoff Philipp Groene Ludwig Ney Daniela Hauer Source Type: research
COVID-19 in obstetric anesthesia : Prospective surveillance of peripartum infections with SARS-CoV-2 and peripartum course of disease in affected women
CONCLUSION: The number of pregnant women infected with SARS-CoV‑2 was at a very low level at the time of delivery, with only sporadic suspected or confirmed cases. Due to the lack of comprehensive testing in the first survey period, however, a certain number of asymptomatic cases are to be assumed. Of the cases 68% presented as asymptomatic or as mild courses of disease but the data showed that even in young healthy patients without the presence of typical risk factors, serious progression can occur. These outcomes should raise awareness for anesthesiologists, obstetricians, pediatricians and intensive care physicians to...
Source: Der Anaesthesist - November 23, 2021 Category: Anesthesiology Authors: Magdalena Sitter Tobias Schlesinger Ann-Kristin Reinhold Axel Scholler Christian von Heymann Sabine Welfle Catharina Bartmann Achim W öckel Stefan Kleinschmidt Sven Schneider Andr é Gottschalk Susanne Greve Julius Z Wermelt Roland Wiener Frank Schulz Da Source Type: research
Development of a giant bulla under spontaneous breathing by self-inflicted lung injury in a patient with COVID-19 pneumonia
Anaesthesist. 2021 Nov 22. doi: 10.1007/s00101-021-01072-w. Online ahead of print.ABSTRACTThe outbreak of SARS-CoV‑2 and the associated COVID-19 pandemic pose major challenges to healthcare systems worldwide. New data on diagnosis, clinical presentation and treatment of the disease are published on a daily basis. This case report describes the fatal course of severe COVID-19 pneumonia in an 81-year-old patient with no previous pulmonary disease who developed a giant bulla during non-invasive high-flow oxygen therapy. Virus-induced diffuse destruction of alveolar tissue or patient self-inflicted lung injury (P-SILI) are d...
Source: Der Anaesthesist - November 23, 2021 Category: Anesthesiology Authors: Nicholas Moellhoff Philipp Groene Ludwig Ney Daniela Hauer Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12:1-8. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical ...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12:1-8. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical ...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12:1-8. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical ...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12:1-8. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical ...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12:1-8. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical ...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical sett...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical sett...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis?
Anaesthesist. 2021 Nov 12. doi: 10.1007/s00101-021-01067-7. Online ahead of print.ABSTRACTTo date no biomarker has been identified bringing together perfect sensitivity and specificity to discriminate between inflammation and infections. Since the 1930s new markers of tissue damage and endothelial damage have been identified but which are incapable of identifying infections in every clinical setting to enable initiation of early antibiotic treatment. In this review the most important classical biomarkers and upcoming new PCR-based approaches are addressed. These markers are highlighted with respect to special clinical sett...
Source: Der Anaesthesist - November 12, 2021 Category: Anesthesiology Authors: Johannes Ehler Christoph Busjahn Tobias Sch ürholz Source Type: research
Intraoperative transesophageal echocardiography as monitoring procedure in noncardiac surgery patients
Anaesthesist. 2021 Nov 11. doi: 10.1007/s00101-021-01035-1. Online ahead of print.ABSTRACTTransesophageal echocardiography (TEE) is firmly established in cardiac surgery for diagnostics, hemodynamic monitoring and as a guiding tool. Dynamic and (patho)physiological processes of the heart can be immediately depicted. Ideally, therapeutic changes can be derived. For this reason, TEE is increasingly used in high-risk non-cardiac surgery interventions and in the interventional setting. In the first part of this advanced training series, general aspects regarding TEE examinations as well as indications and contraindications are...
Source: Der Anaesthesist - November 11, 2021 Category: Anesthesiology Authors: V Umrath C Dumps B Rupprecht J Schimpf J Benak Source Type: research
Intraoperative transesophageal echocardiography as monitoring procedure in noncardiac surgery patients
Anaesthesist. 2021 Nov 11. doi: 10.1007/s00101-021-01035-1. Online ahead of print.ABSTRACTTransesophageal echocardiography (TEE) is firmly established in cardiac surgery for diagnostics, hemodynamic monitoring and as a guiding tool. Dynamic and (patho)physiological processes of the heart can be immediately depicted. Ideally, therapeutic changes can be derived. For this reason, TEE is increasingly used in high-risk non-cardiac surgery interventions and in the interventional setting. In the first part of this advanced training series, general aspects regarding TEE examinations as well as indications and contraindications are...
Source: Der Anaesthesist - November 11, 2021 Category: Anesthesiology Authors: V Umrath C Dumps B Rupprecht J Schimpf J Benak Source Type: research
