[Peripartum aortic dissection].
r W Abstract A 29-year-old primagravida developed severe chest pains during labor. An emergency caesarean section was performed as the symptoms persisted. Imaging diagnosis immediately after delivery revealed an acute proximal (type A) aortic dissection. The patient was transferred to the nearest cardiothoracic surgery centre and successful emergency surgical aortic repair was performed. The perioperative course of a type A aortic dissection during pregnancy and labor is complicated by time pressure, diagnostic restrictions until delivery and potentially fatal uterine bleeding during cardiopulmonary bypass and hyp...
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Pachler C, Knez I, Petru E, Dörfler O, Vicenzi M, Toller W Tags: Anaesthesist Source Type: research

[Supraglottic airway devices in emergency medicine : Impact of gastric drainage].
;ller M Abstract This case report describes a life-saving use of a supraglottic airway device (LT-D™-Larynxtubus, VBM Medizintechnik, Sulz, Germany) in an out-of-hospital emergency patient suffering from severe traumatic brain injury. Mechanical ventilation with the laryngeal tube was complicated by repeated airway obstructions and pronounced gastric distension with air as a consequence of oropharyngeal leakage. In this situation pulmonary ventilation of the patient was compromised so that emergency endotracheal intubation became necessary in the resuscitation area with vital indications. In this context the...
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Mann V, Mann ST, Alejandre-Lafont E, Röhrig R, Weigand MA, Müller M Tags: Anaesthesist Source Type: research

[Use of 2 % hyperbaric prilocaine for spinal anesthesia : Sensitivity analysis in outpatient surgery].
CONCLUSIONS: For German framework conditions the use of hyperbaric prilocaine 2 % can provide an economical advantage compared to the use of hyperbaric bupivacaine 0.5 % if staff assignment can be flexible. PMID: 23535895 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Vagts DA, Bley CH, Mutz CW Tags: Anaesthesist Source Type: research

[Anesthesia for electroconvulsive therapy].
Abstract Electroconvulsive therapy is a well-established form of treatment for a broad spectrum of severe psychiatric disorders. The treatment, in which a generalized epileptic seizure is provoked by electrical stimulation of the brain, is performed with the patient under anesthesia and muscle relaxation. Therefore, sufficient knowledge of the physiological and pharmacological characteristics is an essential requirement for safe anesthesia. The following review is intended to provide some new aspects of the procedure and management of anesthesia. PMID: 23558716 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Grundmann U, Schneider SO Tags: Anaesthesist Source Type: research

[Quality of results of therapy of acute respiratory failure : Changes over a period of two decades].
Abstract Progress in intensive care (ICU) treatment of acute respiratory distress syndrome (ARDS) over the last 20 years includes the introduction of extracorporeal membrane oxygenation (ECMO) for CO2 removal and the widespread use of evidence-based lung-protective ventilatory strategies. Little is known, however, about whether these changes have resulted in improvements in short-term and long-term outcome of acute respiratory distress syndrome (ARDS) within the two decades after introduction. In a retrospective study 167 long-term survivors of severe ARDS who were transferred to the clinic for anesthesiology of t...
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Briegel I, Dolch M, Irlbeck M, Hauer D, Kaufmann I, Schelling G Tags: Anaesthesist Source Type: research

[International guidelines of the Surviving Sepsis Campaign : Update 2012].
This article discusses the most important amendments in the first two sections and delving deeper into the guidelines. PMID: 23558718 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Briegel J, Möhnle P Tags: Anaesthesist Source Type: research

[Disorders of serum sodium in emergency patients : Salt in the soup of emergency medicine].
Abstract Electrolyte disorders are common and potentially fatal laboratory findings in emergency patients. Approximately 20 % of patients in the emergency department present with either hyponatremia or hypernatremia. Recently it was shown that disorders of serum sodium are not only an expression of the severity of the underlying disease but independent predictors for the outcome of patients. They directly influence patient daily life by causing not only gait and concentration disturbances but also an increased tendency to fall together with a reduced bone mass. Given these new data it is even more important...
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Lindner G, Exadaktylos AK Tags: Anaesthesist Source Type: research

[Transfusion-related acute lung injury].
Abstract Transfusion-related acute lung injury (TRALI) developed into the leading cause of transfusion-related morbidity and mortality after the first description by Popovsky et al. approximately three decades ago. It was the most frequent reason for transfusion-related fatalities worldwide before implementation of risk minimization strategies by donor selection. Plasma-rich blood products, such as fresh frozen plasma and apheresis platelets seem to be the leading triggers of TRALI. Hypoxemia and development of pulmonary edema within 6 h of transfusion are the diagnostic criteria for TRALI. The differentiatio...
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Tank S, Sputtek A, Kiefmann R Tags: Anaesthesist Source Type: research

[Erratum to: Nutrition in intensive care medicine : Part 2: special nutritional problems].
PMID: 23558722 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Hecker M, Felbinger TW, Mayer K Tags: Anaesthesist Source Type: research

[Mass casualty incidents : Preparedness of German soccer arenas].
CONCLUSIONS: Most of the participating arenas were adequately staffed to manage the first phase of MCIs but in contrast command structures and transport capacities often focused on individual emergencies. Although most of the participants stated that they planned the resources provision according to well established algorithms, the resources actually available at the arenas varied considerably. The frequency of MCIs in soccer arenas was surprisingly high in contrast to the frequency of MCI-related drills. PMID: 23576092 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Luiz T, Preisegger T, Madler C Tags: Anaesthesist Source Type: research

[TRAILI - A lecture for hemovigilance].
PMID: 23595793 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 1, 2013 Category: Anesthesiology Authors: Biscoping J Tags: Anaesthesist Source Type: research

[Midazolam for premedication in pediatric patients: pros and cons debate].
r M PMID: 23475173 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Jöhr M Tags: Anaesthesist Source Type: research

[Faulty internal tube in a co-axial ventilation tube system: cause of a massive postoperative hypercapnia].
This article presents the case of a patient with massive postoperative hypercapnia during mechanical ventilation in the intensive care unit (ICU). With normal tidal volumes and clearly visible chest movements, adequate findings with regard to auscultation, oxygenation and correct respirator settings, no cause for the increasing hypercapnia was initially found; however, replacement of the respirator led to a return to normal carbon dioxide levels. When checking the replaced respirator a service technician found the cause of the respirator failure: the internal tube of the co-axial ventilation system was faulty leading to an...
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Günther JH, Börning P, Bahlmann L Tags: Anaesthesist Source Type: research

[Intraneural injection of local anesthetics: importance for a successful nerve block].
PMID: 23475175 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Kessler P Tags: Anaesthesist Source Type: research

[Nutrition in intensive care medicine: Part 2: special nutritional problems].
Abstract Therapy of intensive care patients is often complicated by co-morbidities or complex systemic disorders such as sepsis. The necessity to generate an individualized nutritional regime has gained in importance in recent years as this essential part of supportive care has a direct impact on the prognosis of the patient. In the present article a special focus is put on particular questions of nutritional aspects of intensive care patients. The current guidelines and study data on disorders relevant in intensive care medicine, such as acute or chronic renal and liver failure, acute respiratory distress syndrom...
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Hecker M, Felbinger TW, Mayer K Tags: Anaesthesist Source Type: research

[Actually a routine matter: ischemia after catheterization of the radial artery].
This article discusses the risks associated with invasive blood pressure monitoring and treatment options in cases of critical ischemia. The authors conclude that there is no consensus concerning optimal treatment and that a discussion on options for preoperative risk assessment and quickest possible recognition of such complications is worthwhile. Despite the risk of ischemia invasive blood pressure monitoring is an indispensable procedure. PMID: 23483231 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Pasternak I, Rees M, Steinauer A, Plaschy S, Hillermann T Tags: Anaesthesist Source Type: research

Intra-articular injection of levobupivacaine.
PMID: 23494020 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Zink W, Zausig YA, Graf BM Tags: Anaesthesist Source Type: research

[Distal sciatic nerve blocks: randomized comparison of nerve stimulation and ultrasound guided intraepineural block].
In this study 250 adult patients were randomly allocated either to the nerve stimulation group (group NS, n = 125) or to the ultrasound guidance group (group US, n = 125). The sciatic nerve was anesthetized with 20 ml prilocaine 1% and 10 ml ropivacaine 0.75%. In the US group the goal was an intraepineural needle position. In the NS group progress of the block was observed by a second physician using ultrasound imaging but blinded for the investigator performing the nerve stimulation. The main outcome variables were time until readiness for surgery (performance time and onset time), su...
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Seidel R, Natge U, Schulz J Tags: Anaesthesist Source Type: research

[Regional anesthesia in patients with pre-existing infections or immunosuppression].
Abstract Regional anesthesia is the most effective procedure for acute pain therapy. Whether neuraxial and peripheral blocks in patients with pre-existing infectious conditions, immune deficits or other risk factors increase the risk of additional infections is unclear. Analyzing the available literature currently seems to indicate that the incidence of severe infectious complications is generally low. Diabetes, steroid therapy or malignant diseases are apparently present in many cases in which infections associated with regional anesthesia and analgesia have been described. A strict contraindication in patients w...
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: List F, Kessler P, Volk T Tags: Anaesthesist Source Type: research

[Premedication with midazolam: indispensable and good?].
PMID: 23515534 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Machotta A, Schneider G Tags: Anaesthesist Source Type: research

Intra-articular injection of levobupivacaine. Reply from the authors.
PMID: 23630981 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 1, 2013 Category: Anesthesiology Authors: Erden IA Tags: Anaesthesist Source Type: research

[Dealing with massive bleeding and associated perioperative coagulopathy : Recommendations for action of the German Society of Anaesthesiology and Intensive Care Medicine.]
[Dealing with massive bleeding and associated perioperative coagulopathy : Recommendations for action of the German Society of Anaesthesiology and Intensive Care Medicine.] Anaesthesist. 2013 Feb 15; Authors: Grottke O, Frietsch T, Maas M, Lier H, Rossaint R Abstract Massive bleeding with coagulopathy and hemorrhagic shock poses a potential threat to life in numerous clinical settings. Optimal treatment including the prevention of exsanguination necessitates a standardized and interdisciplinary approach. Several studies have shown the importance of massive transfusion protocols and standardized coagulation...
Source: Der Anaesthesist - February 15, 2013 Category: Anesthesiology Authors: Grottke O, Frietsch T, Maas M, Lier H, Rossaint R Tags: Anaesthesist Source Type: research

[Efficacy of a novel warming blanket : Prospective randomized trial.]
[Efficacy of a novel warming blanket : Prospective randomized trial.] Anaesthesist. 2013 Feb 14; Authors: Brandes IF, Müller C, Perl T, Russo SG, Bauer M, Bräuer A Abstract BACKGROUND: Perioperative hypothermia is a common complication of general anesthesia and occurs in up to 50 % of patients during ear, nose and throat (ENT) surgery. In this prospective, randomized controlled study the hypothesis that a new conductive warming blanket (Barrier® EasyWarm®, Mölnlycke Health Care Erkrath, Germany) is better in reducing the incidence of perioperative hypothermia in ENT sur...
Source: Der Anaesthesist - February 14, 2013 Category: Anesthesiology Authors: Brandes IF, Müller C, Perl T, Russo SG, Bauer M, Bräuer A Tags: Anaesthesist Source Type: research

[Post-dural puncture headache.]
Abstract Headache following dural puncture is a typical complication of neuraxial analgesia and can impair the ability to perform activities of daily living up to incapacitation. The use of thin, atraumatic needles and special puncture techniques (e.g. reinsertion of the stylet) can prevent the majority of post-dural puncture headaches (PDPH). One of the most effective measures to prevent headache after accidental dural puncture is the intrathecal or epidural administration of morphine. When the diagnosis of PDPH is confirmed after excluding relevant differential diagnoses, some of which are potentially life-threa...
Source: Der Anaesthesist - February 13, 2013 Category: Anesthesiology Authors: Radke K, Radke OC Tags: Anaesthesist Source Type: research

Arthroscopic shoulder surgery under general anesthesia with brachial plexus block : Postoperative respiratory dysfunction of combined obstructive and restrictive pathology.
Abstract OBJECTIVE: Changes in respiratory parameters and pulmonary function tests were evaluated after shoulder arthroscopic surgery with brachial plexus block (BPB). The purpose of this study was to identify the mechanism of respiratory dysfunction after this type of surgery. METHODS: Patients undergoing arthroscopic rotator cuff repair under general anesthesia (GA) with BPB were enrolled in the arthroscopy group (n = 30) while those undergoing open reduction of a clavicle or humerus fracture under GA were enrolled in the control group (n = 30). Forced vital...
Source: Der Anaesthesist - February 13, 2013 Category: Anesthesiology Authors: Gwak MS, Kim WH, Choi SJ, Lee JJ, Ko JS, Kim GS, Kim YI, Kim MH Tags: Anaesthesist Source Type: research

[Treatment of a pregnant patient after multiple trauma : Rare combination with thrombotic thrombocytopenic purpura.]
This article describes the case of a 36-year-old pregnant woman referred to this hospital suffering from multiple trauma with severe liver rupture. Stabilization was achieved after an emergency Caesarean section and packing of the liver. Recurrent massive bleeding from the liver occurred after depacking and was treated successfully with recombinant factor VIIa. The concomitant TTP was treated by transfusion of fresh frozen plasma and corticosteroids. Rapid initiation of therapy was the goal to achieve hemostasis and prevent aggravation of the coagulation disorder and an unfavourable outcome despite severe thrombocytopenia....
Source: Der Anaesthesist - February 13, 2013 Category: Anesthesiology Authors: Haffner E, Pietsch U, Fösel T, Lindemann W Tags: Anaesthesist Source Type: research

[Anesthesia-induced neurotoxicity : Statement of the Scientific Working Groups for Pediatric Anesthesia and Neuroanesthesia.]
[Anesthesia-induced neurotoxicity : Statement of the Scientific Working Groups for Pediatric Anesthesia and Neuroanesthesia.] Anaesthesist. 2013 Feb 13; Authors: Becke K, Schreiber M, Philippi-Höhne C, Strauß J, Engelhard K, Sinner B PMID: 23400713 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - February 13, 2013 Category: Anesthesiology Authors: Becke K, Schreiber M, Philippi-Höhne C, Strauß J, Engelhard K, Sinner B Tags: Anaesthesist Source Type: research

[Caesarean sections under regional anesthesia : Pros and cons of supplementary oxygen.]
[Caesarean sections under regional anesthesia : Pros and cons of supplementary oxygen.] Anaesthesist. 2013 Feb 9; Authors: Aust H, Zemlin M, Woernle F, Wulf H, Rüsch D Abstract The routine administration of supplemental oxygen to women undergoing elective caesarean section under regional anesthesia in order to optimize oxygen supply to the fetus is common anesthetic practice in many German hospitals. However, this practice has been controversially discussed in the non-German literature for many years. This review presents and discusses the pros and cons of routinely providing supplemental oxygen to a ...
Source: Der Anaesthesist - February 9, 2013 Category: Anesthesiology Authors: Aust H, Zemlin M, Woernle F, Wulf H, Rüsch D Tags: Anaesthesist Source Type: research

[Neurotoxicity of general anesthetics in childhood : Does anesthesia leave its mark on premature babies, newborns and infants?]
[Neurotoxicity of general anesthetics in childhood : Does anesthesia leave its mark on premature babies, newborns and infants?] Anaesthesist. 2013 Feb 9; Authors: Sinner B, Becke K, Engelhard K Abstract Many animal experiments have shown that anesthetics can have a neurotoxic effect on immature brains because they induce apoptosis and influence neurogenesis and synaptogenesis. In animal experiments this has substantial implications for the neurocognitive functions of animals in later life. Whether these results of animal experiments can be transferred to humans is currently the subject of intensive researc...
Source: Der Anaesthesist - February 9, 2013 Category: Anesthesiology Authors: Sinner B, Becke K, Engelhard K Tags: Anaesthesist Source Type: research

[Pulmonary arterial hypertension.]
Authors: PMID: 23392219 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - February 9, 2013 Category: Anesthesiology Tags: Anaesthesist Source Type: research

[Tools for avoidance of medication errors in pediatric emergencies.]
Authors: PMID: 23389258 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - February 8, 2013 Category: Anesthesiology Tags: Anaesthesist Source Type: research

[Successful infection control in regional anesthesia procedures : Observational survey after introduction of the DGAI hygiene recommendations.]
This study was carried out with special respect to infectious complications (inflammation and infection). RESULTS: In the years 2002-2004 unexpectedly high rates of infectious complications were observed in 3,491 cPNBs with 146 inflammations (4.2 %) and 112 infections (3.2 %). Based on these alarming findings the existing hygiene regime was revised. The innovations were incorporated into the "Hygiene recommendations for the initiation and continued care of regional anaesthetic procedures" of the German Society for Anaesthesiology and Intensive Care Medicine (Deutsche Gesellschaft f&u...
Source: Der Anaesthesist - February 6, 2013 Category: Anesthesiology Authors: Reisig F, Neuburger M, Zausig YA, Graf BM, Büttner J Tags: Anaesthesist Source Type: research

[New tool for drug dosing in life-threatening pediatric emergencies.]
PMID: 23377370 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - February 3, 2013 Category: Anesthesiology Authors: Zugck TO Tags: Anaesthesist Source Type: research

[Developmental abnormalities in children following surgery under general anesthesia : Anesthesiological problem?]
[Developmental abnormalities in children following surgery under general anesthesia : Anesthesiological problem?] Anaesthesist. 2013 Jan 27; Authors: Eckle VS, Grasshoff C PMID: 23354489 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - January 27, 2013 Category: Anesthesiology Authors: Eckle VS, Grasshoff C Tags: Anaesthesist Source Type: research

[Anesthetist's briefing check : Tool to improve patient safety in the operating room.]
In conclusion, it appears that patient safety can be significantly improved with little time effort of 3-5 min per patient. A prospective trial will be conducted to confirm the impact of this measure on improvements in patient safety. PMID: 23354486 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - January 26, 2013 Category: Anesthesiology Authors: Trimmel H, Fitzka R, Kreutziger J, von Goedecke A Tags: Anaesthesist Source Type: research

[Fatal incidents by crowd crush during mass events : (Un)preventable phenomenon.]
CONCLUSIONS: Unfortunately, there is no patent remedy to completely prevent fatal accidents by a crowd crush at mass events. If planning is initiated early, sufficient material and personnel reserves are kept in reserve and despite conflicting interests of the organizers, the host community, security, police and emergency medical services, a joint concept is designed and followed, the risk of a severe incident can be kept to a minimum. Each involved party including the spectators have to be aware of their responsibility in order to contribute to the success and safety of the mass event. A comprehensive and critical ...
Source: Der Anaesthesist - January 26, 2013 Category: Anesthesiology Authors: Wagner U, Fälker A, Wenzel V Tags: Anaesthesist Source Type: research

[Take a position on changes in therapy aims and limiting therapy : Actio moralis practiced in intensive care medicine.]
[Take a position on changes in therapy aims and limiting therapy : Actio moralis practiced in intensive care medicine.] Anaesthesist. 2013 Jan 26; Authors: Bein T PMID: 23354488 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - January 26, 2013 Category: Anesthesiology Authors: Bein T Tags: Anaesthesist Source Type: research

[Off-label use of drugs in pediatric emergencies : Limitations and grey areas of drug approval.]
[Off-label use of drugs in pediatric emergencies : Limitations and grey areas of drug approval.] Anaesthesist. 2013 Jan 25; Authors: Erker CG, Möllmann M Abstract In the medical treatment of children drugs are frequently used outside the boundaries of the approved licensing and use under the terms of off-label use is possible. However, this requires critical reasoning and experience with the drug involved. With help of a traffic light colored spreadsheet this article illustrates the limitations, problems and possibilities of pharmacotherapy in pediatric emergencies or pediatric anesthesia. Of the 45 e...
Source: Der Anaesthesist - January 25, 2013 Category: Anesthesiology Authors: Erker CG, Möllmann M Tags: Anaesthesist Source Type: research

[Secondary sclerosing cholangitis after multiple trauma and long-term intensive care treatment : Case report of a characteristic course.]
This article reports on a patient who needed intensive care treatment because of multiple trauma. The patient had no preexisting liver disease but developed secondary sclerosing cholangitis and finally died. The etiology, diagnosis and therapeutic options of this clinical picture are discussed and a review of the literature is presented. PMID: 23340951 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - January 24, 2013 Category: Anesthesiology Authors: Seemann M, Kirchner G, Bele S, Sinner B, Graf B, Kieninger M Tags: Anaesthesist Source Type: research

[Regional anesthesia for patients with infections or immunosuppression : Risk-benefit assessment.]
[Regional anesthesia for patients with infections or immunosuppression : Risk-benefit assessment.] Anaesthesist. 2013 Jan 16; Authors: Büttner J PMID: 23319270 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - January 16, 2013 Category: Anesthesiology Authors: Büttner J Tags: Anaesthesist Source Type: research

[Postoperative assessment of daily energy expenditure : Comparison of two methods.]
CONCLUSIONS: The SWA showed reliable concordance with daily REE estimated by HBE in normometabolic postsurgery patients. This noninvasive, convenient and easy to handle device may be helpful in determining energy requirements as part of metabolic monitoring. Further research is needed to validate the method in patients with severe metabolic disturbances. The energetic requirements of patients with postoperative t-PDA were not different from those with intravenous pain therapy. PMID: 23319271 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - January 16, 2013 Category: Anesthesiology Authors: Dummler R, Zittermann A, Schäfer M, Emmerich M Tags: Anaesthesist Source Type: research

Ventilatory strategies in septic patients : Results from a nationwide observational trial.
CONCLUSIONS: This representative survey revealed that severe sepsis or septic shock was frequently associated with acute lung injury. Different ventilatory modes did not affect mortality. The tidal volume to inspiratory pressure ratio but not the PF ratio was independently associated with mortality. PMID: 23319272 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - January 16, 2013 Category: Anesthesiology Authors: Schädler D, Elke G, Engel C, Bogatsch H, Frerichs I, Kuhlen R, Rossaint R, Quintel M, Scholz J, Brunkhorst FM, Loeffler M, Reinhart K, Weiler N, For the German Competence Network Sepsis (SepNet) Tags: Anaesthesist Source Type: research

[Onset of a fulminant malignant hyperthermia crisis : Case report of a 74-year-old patient with previously subclinical central core disease.]
[Onset of a fulminant malignant hyperthermia crisis : Case report of a 74-year-old patient with previously subclinical central core disease.] Anaesthesist. 2012 Dec 19; Authors: Wejbora M, Bornemann-Cimenti H, Lessel D, Mandl C, Voit-Augustin H, Schwarz G Abstract Malignant hyperthermia (MH) is a latent, autosomal dominant inherited syndrome of skeletal musculature which results in excessive hypermetabolism induced by halogenated anesthetic agents and depolarizing muscle relaxants and is caused by an uncontrolled intramuscular calcium release. This case report focuses on the description of symptoms of a fu...
Source: Der Anaesthesist - December 19, 2012 Category: Anesthesiology Authors: Wejbora M, Bornemann-Cimenti H, Lessel D, Mandl C, Voit-Augustin H, Schwarz G Tags: Anaesthesist Source Type: research

["The sweet poison" : Diabetes mellitus in the perioperative phase.]
["The sweet poison" : Diabetes mellitus in the perioperative phase.] Anaesthesist. 2012 Dec 7; Authors: Lange M PMID: 23223842 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - December 7, 2012 Category: Anesthesiology Authors: Lange M Tags: Anaesthesist Source Type: research

[Video laryngoscopy : Deep insights].
[Video laryngoscopy : Deep insights]. Anaesthesist. 2012 Dec;61(12):1016 Authors: Hofstetter C PMID: 23179364 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - December 1, 2012 Category: Anesthesiology Authors: Hofstetter C Tags: Anaesthesist Source Type: research

[Practical diagnostics of acid-base disorders : Part II: Complex metabolic disturbances].
[Practical diagnostics of acid-base disorders : Part II: Complex metabolic disturbances]. Anaesthesist. 2012 Dec;61(12):1067-78 Authors: Deetjen P, Lichtwarck-Aschoff M Abstract The second part of this overview focuses on how to assess more complex metabolic causes of acid-base imbalance. This is precisely the battlefield where most of the fiery debates between the Copenhagen, the Boston and the Stewart schools aroused. While the first part of the overview merged the practical strengths of the three different approaches, in part II it will be shown how the Stewart approach in particular helps in understand...
Source: Der Anaesthesist - December 1, 2012 Category: Anesthesiology Authors: Deetjen P, Lichtwarck-Aschoff M Tags: Anaesthesist Source Type: research

[Functional separation of the lungs : Ventilation strategy for unilateral blunt force thoracic trauma].
[Functional separation of the lungs : Ventilation strategy for unilateral blunt force thoracic trauma]. Anaesthesist. 2012 Dec;61(12):1045-8 Authors: Hammersen G, Beiderlinden M Abstract Independent lung ventilation was performed in a patient with severe hypoxemia (oxygenation ratio p(a)O(2)/F(I)O(2) 61 mmHg) due to unilateral blunt chest trauma and consecutive consolidation of the injured lung. Recruitment and immobilization of the consolidated lung was achieved by functional separation of both lungs with application of a mean airway pressure (p(mean)) of 28 mbar in combination with low frequenc...
Source: Der Anaesthesist - December 1, 2012 Category: Anesthesiology Authors: Hammersen G, Beiderlinden M Tags: Anaesthesist Source Type: research

[Silent cardiotocogram during general anesthesia : Indication for emergency Cesarean section?].
[Silent cardiotocogram during general anesthesia : Indication for emergency Cesarean section?]. Anaesthesist. 2012 Dec;61(12):1049-53 Authors: Bock H, List E, Kosmala A, Lex B, Moratin P Abstract This case report of a silent cardiotocogram (CTG) registration during general anesthesia in a 33-week-pregnant patient undergoing non-obstetric surgery demonstrates the possibility of misinterpretation whereby typical CTG patterns of fetal reactions to anesthetics can be misinterpreted as fetal hypoxia or even asphyxia. PMID: 23223840 [PubMed - in process] (Source: Der Anaesthesist)
Source: Der Anaesthesist - December 1, 2012 Category: Anesthesiology Authors: Bock H, List E, Kosmala A, Lex B, Moratin P Tags: Anaesthesist Source Type: research

[Severe hypernatremia : Case report, pathophysiology and therapy].
[Severe hypernatremia : Case report, pathophysiology and therapy]. Anaesthesist. 2012 Dec;61(12):1054-8 Authors: Schneider A, Reiner M, Kolibay F Abstract The case of a female patient with a suprasellar optic glioma is reported, who was admitted to the intensive care unit due to decompensated diabetes insipidus with hypernatremia of 194 mmol/l. The sodium concentration was reduced slowly over 4 days and the patient recovered without sequelae. Based on this case the article deals with the pathophysiology and therapy of hypernatremia. An increase in extracellular osmolarity leads to augmented production...
Source: Der Anaesthesist - December 1, 2012 Category: Anesthesiology Authors: Schneider A, Reiner M, Kolibay F Tags: Anaesthesist Source Type: research

[Dexmedetomidine : Pharmacokinetics and pharmacodynamics].
[Dexmedetomidine : Pharmacokinetics and pharmacodynamics]. Anaesthesist. 2012 Dec;61(12):1059-66 Authors: Ihmsen H, Saari TI Abstract Dexmedetomidine is a highly selective, potent α(2)-adrenoceptor agonist which was approved in 2011 by the European Medicines Agency for sedation of patients in intensive care units (ICU). Dexmedetomidine exhibits sedative as well as analgesic and anxiolytic effects. Recent studies suggest that dexmedetomidine may be an alternative to midazolam in long-term ICU sedation. This review summarizes the pharmacokinetics and pharmacodynamics of dexmedetomidine particularly in ...
Source: Der Anaesthesist - December 1, 2012 Category: Anesthesiology Authors: Ihmsen H, Saari TI Tags: Anaesthesist Source Type: research