["Terminal" dehydration, part  1 : Differential diagnosis and body of evidence].
This article provides an overview of possible causes of dehydration at the end of life and places special emphasis on "terminal" dehydration in the dying. Empirical attitudes of healthcare professionals and persons concerned (patients and relatives) as well as evidence-based findings on "terminal" dehydration are elucidated and the limitations are described. Finally, it is concluded that the appropriate detection of the mode of dehydration (including its underlying pathophysiology) as well as the clinical evaluation of the "reversibility" of the symptoms after fluid therapy, is of central impo...
Source: Der Anaesthesist - August 30, 2018 Category: Anesthesiology Authors: Suchner U, Reudelsterz C, Gog C Tags: Anaesthesist Source Type: research

[Hemodynamic effects of cafedrine/theodrenaline on anesthesia-induced hypotension].
CONCLUSION: In anesthesia-induced hypotension caf/theo effectively increased the mean arterial blood pressure by combined effects on preload, contractility, and afterload without altering cardiovascular efficiency. PMID: 30132111 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - August 21, 2018 Category: Anesthesiology Authors: Weitzel M, Hammels P, Schorer C, Klingler H, Weyland A Tags: Anaesthesist Source Type: research

[Systematic analysis of airway registries in emergency medicine].
CONCLUSION: This study identified eleven EARs that sometimes widely differed concerning inclusion periods, inclusion criteria, definition of complications and application of newer methods of emergency airway management. Thus, comparability of the reported results and first-pass success rates is only possible to a limited extent. The authors therefore advocate the initiation of an airway registry in emergency medicine in German-speaking countries. PMID: 30105516 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - August 13, 2018 Category: Anesthesiology Authors: Girrbach FF, Hilbig F, Michael M, Bernhard M Tags: Anaesthesist Source Type: research

[High pain expectation and impairment from pre-existing pain are risk factors for severe postoperative pain : Results of a  study using the Lübeck Pain Risk Questionnaire].
[High pain expectation and impairment from pre-existing pain are risk factors for severe postoperative pain : Results of a study using the Lübeck Pain Risk Questionnaire]. Anaesthesist. 2018 Aug 13;: Authors: Vahldieck C, Lindig M, Nau C, Hüppe M Abstract BACKGROUND: The intensity of postoperative pain is characterized by large interindividual variability. Furthermore, strong postoperative pain is known to influence physical recovery after surgery. High (preoperative) pain expectation and pre-existing pain, which are associated with pain-related disability (impairing pain) are risk fact...
Source: Der Anaesthesist - August 13, 2018 Category: Anesthesiology Authors: Vahldieck C, Lindig M, Nau C, Hüppe M Tags: Anaesthesist Source Type: research

[Perspectives for anesthesiologists in hospital hygiene].
DISCUSSION: The program was able to increase the number of infection control physicians in a relatively short period of time; however, to guarantee a comparable quality of education it is necessary to standardize the requirements on a national level. The supervision also needs to be further specified. A new program is currently being developed by the German Medical Association, which will hopefully lead to an improvement of the educational program. Special strengths of the new infection control physicians are the broad clinical experience as well as the additional qualifications in antibiotic stewardshi...
Source: Der Anaesthesist - August 13, 2018 Category: Anesthesiology Authors: Bonsignore M, Alefelder C, Pausner N, Gastmeier P, Nachtigall I Tags: Anaesthesist Source Type: research

[Airway management for lung separation in thoracic surgery : An  update].
This article presents the most commonly used methods for lung isolation. These include the double lumen tube, the bronchus blockers by Arndt and Cohen, the EZ blocker, the Uniblocker, the Univent tube and the VivaSight-DL™. The effects of the one-lung ventilation are not described in detail and for this the reader should refer to the appropriate literature. This article is intended to provide an overview of the various possibilities for lung separation, especially for physicians in continued medical education and also for physicians who rarely use these procedures. PMID: 30083992 [PubMed - as supplied by publish...
Source: Der Anaesthesist - August 6, 2018 Category: Anesthesiology Authors: Meggiolaro KM, Wulf H, Feldmann C, Wiesmann T, Schubert AK, Risse J Tags: Anaesthesist Source Type: research

[Comments on: Fluid management for major general surgical interventions: liberal vs. restrictive].
PMID: 30083993 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - August 6, 2018 Category: Anesthesiology Authors: Van Waesberghe J, Coburn M Tags: Anaesthesist Source Type: research

[Intensive care studies from 2017/2018].
er T PMID: 30083994 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - August 6, 2018 Category: Anesthesiology Authors: Reuß CJ, Bernhard M, Beynon C, Hecker A, Jungk C, Nusshag C, Weigand MA, Michalski D, Brenner T Tags: Anaesthesist Source Type: research

[Drugs for intravenous induction of anesthesia: ketamine, midazolam and synopsis of current hypnotics].
Abstract Ketamine and midazolam form the endpoint of a series of articles about intravenous induction of anesthesia . Both substances can be used as single induction hypnotic drugs; however, in practice, this is unusual. Both substances, with the exception of a few very specific indications and clinical situations, are more frequently used in combination or with one of the more common alternatives propofol, barbiturates and etomidate. The reasons are the activity and side effects of both substances and their positive characteristics are used more as a supplement. In the concluding comparison the five dis...
Source: Der Anaesthesist - August 1, 2018 Category: Anesthesiology Authors: Halbeck E, Dumps C, Bolkenius D Tags: Anaesthesist Source Type: research

[Airway separation and one-lung ventilation : A special challenge for anesthetists].
PMID: 30027477 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - July 19, 2018 Category: Anesthesiology Authors: Kammerer T Tags: Anaesthesist Source Type: research

[Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR) : Consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC].
Riessen R, Thiele H Abstract Extracorporeal cardiopulmonary resuscitation (eCPR) may be considered as a rescue attempt for highly selected patients with refractory cardiac arrest and potentially reversible etiology. Currently there are no randomized, controlled studies on eCPR, and valid predictors of benefit and outcome which might guide the indication for eCPR are lacking. Currently selection criteria and procedures differ across hospitals and standardized algorithms are lacking. Based on expert opinion, the present consensus statement provides a proposal for a standardized treatment algorithm for eCPR...
Source: Der Anaesthesist - July 16, 2018 Category: Anesthesiology Authors: Michels G, Wengenmayer T, Hagl C, Dohmen C, Böttiger BW, Bauersachs J, Markewitz A, Bauer A, Gräsner JT, Pfister R, Ghanem A, Busch HJ, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen Tags: Anaesthesist Source Type: research

[Ready for the hybrid operating room?]
her M PMID: 29974134 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - July 4, 2018 Category: Anesthesiology Authors: Raspé C, Bucher M Tags: Anaesthesist Source Type: research

[Rapid sequence induction and intubation in patients with risk of aspiration : Recommendations for action for practical management of anesthesia].
DISCUSSION: The consideration of all practical, clinical procedures in patients at risk for aspiration represents an effective prevention of pulmonary aspiration during the induction of anesthesia. These include the optimal drug pre-treatment with antacids (e. g. sodium citrate) for highly aspiration-endangered and proton pump inhibitors or H2 blockers in other patients the evening before. Each patient should be examined and explained prior to RSI according to the recommendations of the National German Society of Anesthesiology for preoperative evaluation. A RSI should be performed in patients with no 2h liquid and ...
Source: Der Anaesthesist - June 29, 2018 Category: Anesthesiology Authors: Eichelsbacher C, Ilper H, Noppens R, Hinkelbein J, Loop T Tags: Anaesthesist Source Type: research

[Hybrid operating theater].
Abstract A hybrid suite is an operating theater with imaging equipment equivalent to that used in an angiography suite with computed tomography (CT) and magnetic resonance imaging (MRI). They are often situated outside the operating room area and typically serve as multifunctional rooms designed to support a variety of catheter-based endovascular procedures and open surgery to be performed in the same location. The possibility to perform these in the same location facilitates the combination of both approaches to so-called hybrid procedures. Typical clinical applications of hybrid suites are cardiac, thoracic...
Source: Der Anaesthesist - June 29, 2018 Category: Anesthesiology Authors: Fuchs-Buder T, Settembre N, Schmartz D Tags: Anaesthesist Source Type: research

[Performance of prehospital emergency anesthesia and airway management : An online survey].
CONCLUSION: The results of the survey demonstrate heterogeneity in RSI techniques used by EMS physicians in Germany. Medical equipment and safe care practices, such as labeling of syringes varied considerably between different service areas. The recommendations of the S1 national guidelines on emergency airway management and anesthesia should be adhered to together with the implementation of local SOPs. PMID: 29959500 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - June 29, 2018 Category: Anesthesiology Authors: Warnecke T, Dobbermann M, Becker T, Bernhard M, Hinkelbein J Tags: Anaesthesist Source Type: research

[S1 guidelines on malignant hyperthermia : Update 2018].
Abstract The prevalence of malignant hyperthermia (MH) in Germany is 1:2000-1:3000 and therefore more common than previously assumed, so that anesthesia personnel will more often be confronted with susceptible patients in the clinical setting. After the initial treatment with 2.5 mg/kg body weight dantrolene, further therapy using up to 10 mg/body weight dantrolene can be indicated for 24 h. Under these circumstances it is important to have a sufficient amount of water available for injection purposes. For outpatient anesthesia a stockage of dantrolene is not necessary as long as the use of MH trigger substa...
Source: Der Anaesthesist - June 26, 2018 Category: Anesthesiology Authors: Wappler F Tags: Anaesthesist Source Type: research

Implementation of the Sepsis-3 definition in German university intensive care units : A  survey.
CONCLUSION: The results demonstrate the heterogeneity of Sepsis-3 implementation in German intensive care units. Sepsis-3 is finding its way but there is a need for standardized implementation. PMID: 29946857 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - June 26, 2018 Category: Anesthesiology Authors: Keppler U, Schmoch T, Siegler BH, Weigand MA, Uhle F Tags: Anaesthesist Source Type: research

[Bridging anticoagulation in patients receiving vitamin  K antagonists : Current status].
[Bridging anticoagulation in patients receiving vitamin K antagonists : Current status]. Anaesthesist. 2018 Jun 20;: Authors: Schellong SM, Riess H, Spannagl M, Omran H, Schwarzbach M, Langer F, Gogarten W, Bramlage P, Bauersachs RM Abstract Approximately 30% of patients receiving oral anticoagulation using vitamin K antagonists (VKA) require surgery within 2 years. In this context, a clinical decision on the need and the mode of a peri-interventional bridging with heparin is needed. While a few years ago, bridging was almost considered a standard of care, recen...
Source: Der Anaesthesist - June 20, 2018 Category: Anesthesiology Authors: Schellong SM, Riess H, Spannagl M, Omran H, Schwarzbach M, Langer F, Gogarten W, Bramlage P, Bauersachs RM Tags: Anaesthesist Source Type: research

[Pain therapy in intensive care patients].
er W Abstract After intensive care unit (ICU) treatment, the recollection of experienced pain is one of the most burdensome aftermaths. In addition, pain has several negative physiological consequences. The majority of patients report moderate to severe pain while being treated on an ICU, often caused by diagnostic or therapeutic procedures. Pain and its functional consequences during ICU treatment should therefore be systematically recorded and treated. Due to their high analgesic potency, pharmacological pain therapy focuses on opioids; however, gastrointestinal motility disturbance and development of tolerance ...
Source: Der Anaesthesist - May 30, 2018 Category: Anesthesiology Authors: Rose K, Meißner W Tags: Anaesthesist Source Type: research

[Pain therapy for intensive care patients-are we doing everything we can?]
PMID: 29802437 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 25, 2018 Category: Anesthesiology Authors: von Dincklage F Tags: Anaesthesist Source Type: research

[Systemic effects of amide-linked local anesthetics : Old drugs, new magic bullets?]
Abstract Besides the well-known analgesic effects of amide-linked local anesthetics exerted via the inhibition of the voltage-gated sodium channel, these substances also possess a certain number of properties, which bear the potential to positively influence the outcome after surgery. The results of several experimental as well as clinical studies suggest the possibility of an enhanced recovery after surgery, reduction in the incidence of chronic pain, preservation of endothelial barrier function during acute lung injury and the prevention of metastasis of solid tumors by systemic effects of local anesthetic ...
Source: Der Anaesthesist - May 25, 2018 Category: Anesthesiology Authors: Piegeler T, Werdehausen R Tags: Anaesthesist Source Type: research

[Supplement to the etymology of the term "barbiturate"].
[Supplement to the etymology of the term "barbiturate"]. Anaesthesist. 2018 May 25;: Authors: Lewandowski K PMID: 29802439 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 25, 2018 Category: Anesthesiology Authors: Lewandowski K Tags: Anaesthesist Source Type: research

[Patient endangerment due to device diversity? : Discussion of a risk factor based on the results of two surveys of German hospitals].
Discussion of a risk factor based on the results of two surveys of German hospitals]. Anaesthesist. 2018 May 25;: Authors: Lange K, Brinker A, Nowak M, Zöllner C, Lauer W Abstract BACKGROUND: The Federal Institute for Drugs and Medical Devices (BfArM) was notified of an event in which it was not possible to sufficiently ventilate a patient suffering a severe asthma attack. It turned out that the ventilation pressures used by the device for pressure-controlled ventilation were below the values set by the user, which the user was not aware of. The ventilation pressures chosen by the user ...
Source: Der Anaesthesist - May 25, 2018 Category: Anesthesiology Authors: Lange K, Brinker A, Nowak M, Zöllner C, Lauer W Tags: Anaesthesist Source Type: research

[Sepsis detection in emergency medicine : Results of an interprofessional survey on sepsis detection in prehospital emergency medicine and emergency departments].
The objective of this survey was to examine the state of knowledge regarding sepsis among staff working in emergency medicine. MATERIAL AND METHODS: To assess the awareness and knowledge, a paper-based, anonymous survey was conducted among prehospital and emergency department personnel from May to August 2017 in northeastern Germany. Testing of significance was carried out using the χ2-testand Fisher's exact test. RESULTS: Out of 411 persons polled 212 answered (response rate 51.6%) and 24 questionnaires were incomplete and thus excluded. A total of 188 questionnaires were included covering 55 ...
Source: Der Anaesthesist - May 25, 2018 Category: Anesthesiology Authors: Metelmann C, Metelmann B, Scheer C, Gründling M, Henkel B, Hahnenkamp K, Brinkrolf P Tags: Anaesthesist Source Type: research

[Influence of rocuronium dose on the effectiveness of mask ventilation : A prospective, randomized clinical trial].
e T Abstract BACKGROUND: Mask ventilation could improve after administration of muscle relaxants if there is a functional obstruction of the airway, such as laryngospasm, vocal cord closure or opioid-induced muscle rigidity. On the other hand, muscle relaxants could worsen mask ventilation because they induce upper airway collapse; however, clinical studies showed that rocuronium (Roc) improved mask ventilation or it remained unchanged. In most cases Roc 0.06 mg/kgBW was used. OBJECTIVE: The optimal dose of Roc has not been studied; therefore, we studied the quality of mask ventilation with three diffe...
Source: Der Anaesthesist - May 25, 2018 Category: Anesthesiology Authors: Hellmund M, Bajorat J, Machmüller S, Sauer M, Zitzmann A, Reuter DA, Mencke T Tags: Anaesthesist Source Type: research

[Meta-analyses on measurement precision of non-invasive hemodynamic monitoring technologies in adults].
Abstract An ideal non-invasive monitoring system should provide accurate and reproducible measurements of clinically relevant variables that enables clinicians to guide therapy accordingly. The monitor should be rapid, easy to use, readily available at the bedside, operator-independent, cost-effective and should have a minimal risk and side effect profile for patients. An example is the introduction of pulse oximetry, which has become established for non-invasive monitoring of oxygenation worldwide. A corresponding non-invasive monitoring of hemodynamics and perfusion could optimize the anesthesiological treatment...
Source: Der Anaesthesist - May 22, 2018 Category: Anesthesiology Authors: Pestel G, Fukui K, Higashi M, Schmidtmann I, Werner C Tags: Anaesthesist Source Type: research

[Palliative sedation : Development and consensus of a  German language documentation template].
CONCLUSION: This article provides an empirically based, multiprofessional consented documentation template for PS. Core elements of the documentation of PS are the indications and the decision process towards PS. During the treatment, at least the level of sedation and the symptom burden have to be recorded. The documentation of vital signs during PS remains a highly disputed topic. The presented data suggest that especially in outpatient settings and in hospices measuring and documentation of vital parameters is uncommon and therefore is often regarded as not feasible. This template can help to support the medically ...
Source: Der Anaesthesist - May 16, 2018 Category: Anesthesiology Authors: Klein C, Wittmann C, Wendt KN, Ostgathe C, Stiel S Tags: Anaesthesist Source Type: research

Risks and prevention of surgical fires : A  systematic review.
Risks and prevention of surgical fires : A systematic review. Anaesthesist. 2018 May 15;: Authors: Kezze I, Zoremba N, Rossaint R, Rieg A, Coburn M, Schälte G Abstract Surgically induced fire is a life-threatening hazard; this topic has received little attention, although only 3 factors, the so-called fire triad, are needed for surgical fires to occur: an oxidizer, fuel and an ignition source. This systematic review aims to determine the impact of each component and to delegate every staff member an area of responsibility, thus ensuring patient health through prevention or protecti...
Source: Der Anaesthesist - May 15, 2018 Category: Anesthesiology Authors: Kezze I, Zoremba N, Rossaint R, Rieg A, Coburn M, Schälte G Tags: Anaesthesist Source Type: research

[Adequate anti-infective treatment : Importance of individual dosing and application].
This article reviews the background of the individual dosing in intensive care patients and their applicability to the clinical routine. PMID: 29766208 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 15, 2018 Category: Anesthesiology Authors: Brinkmann A, Röhr AC, Köberer A, Fuchs T, Krüger WA, König C, Richter D, Weigand MA, Frey OR Tags: Anaesthesist Source Type: research

[Back to the roots of training and further training in anesthesiology].
PMID: 29761258 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 14, 2018 Category: Anesthesiology Authors: Goetz AE Tags: Anaesthesist Source Type: research

[Sense of Coherence Scale according to Antonovsky as a  possible predictor for return to work for cardiac surgery intensive care patients].
In this study 278 patients (invasive coronary artery bypass graft surgery and/or surgery on heart valves, age 
Source: Der Anaesthesist - May 14, 2018 Category: Anesthesiology Authors: Benstoem C, Wübker R, Lüngen M, Breuer T, Marx G, Autschbach R, Goetzenich A, Schnoering H Tags: Anaesthesist Source Type: research

[Drugs for intravenous induction of anesthesia: barbiturates].
Abstract The discovery of barbituric acid and research on its derivatives have long been of importance in advancements in modern anesthesia. Decades of clinical use of barbiturates worldwide and their abuse has led to an enormous amount of knowledge. Thiopental and methohexital are ultra-short acting derivatives of barbiturates. Their clinical application has been accompanied by an enormous increase in the knowledge of the pharmacology of cerebrally active drugs, in particular gamma-aminobutyric acid (GABAA) receptor and GABA-induced effects on nerve cell membranes. Despite the development of newer substances, thi...
Source: Der Anaesthesist - May 9, 2018 Category: Anesthesiology Authors: Dumps C, Halbeck E, Bolkenius D Tags: Anaesthesist Source Type: research

[Percutaneous and surgical options for mechanical circulatory support in treatment of terminal heart failure].
PMID: 29736554 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 7, 2018 Category: Anesthesiology Authors: Eifert S Tags: Anaesthesist Source Type: research

[Basic manual skills in pediatric anesthesia].
r M PMID: 29736555 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 7, 2018 Category: Anesthesiology Authors: Jöhr M Tags: Anaesthesist Source Type: research

[Correct positioning of central venous catheters in pediatrics : Are current formulae really useful?]
CONCLUSION: The benefit of a formula for daily practice is very limited due to the problem of choosing the right insertion point. The recommended insertion depth should be considered as an indicator and a verification of the CVC tip position should be done using an imaging technique. PMID: 29736556 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 7, 2018 Category: Anesthesiology Authors: Cleff C, Boensch M, Eifinger F, Hinkelbein J Tags: Anaesthesist Source Type: research

[Comments on: Timing of operative treatment of fractures near the hip joint].
PMID: 29728710 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - May 4, 2018 Category: Anesthesiology Authors: Gerards MG, Haraszti B, Hess J, Houpert ACD, Idel PD, Klaeren FN, Krause J, Coburn M Tags: Anaesthesist Source Type: research

[Hemorrhage of the innominate artery during percutaneous dilatation tracheotomy].
e V Abstract The report describes the rare case of a periprocedural hemorrhage during percutaneous dilatation tracheotomy. In the final analysis, the innominate artery could be identified as the source of the hemorrhage. Particular attention must be paid to preprocedural evaluation of the puncture site and the procedure following unexpected hemorrhage. Continuation of the percutaneous tracheotomy, with only a clinical suspicion of a vascular injury while the bleeding source remained undetectable, seemed to be the most reasonable option. In this case the potentially life-threatening hemorrhage could be st...
Source: Der Anaesthesist - April 18, 2018 Category: Anesthesiology Authors: Hulde N, Köppen M, Gratzke M, Kisch-Wedel H, Brenner P, Huge V Tags: Anaesthesist Source Type: research

[Which patients benefit from transport with ongoing cardiopulmonary resuscitation? : Retrospective analysis of 70  patients with refractory preclinical cardiac arrest].
CONCLUSION: Selected patient collectives can benefit from transport to hospital with ongoing cardiopulmonary resuscitation (CPR). PMID: 29666925 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 17, 2018 Category: Anesthesiology Authors: Adler C, Paul C, Hinkelbein J, Michels G, Pfister R, Krings A, Lechleuthner A, Stangl R Tags: Anaesthesist Source Type: research

[Physiological changes during pregnancy].
Abstract The physiological state of a woman experiences multiple changes in the body during pregnancy. These alterations could be of particular importance in the medical care of pregnant women. This review article highlights the physiological developments of various organ systems throughout gestation with a focus on endocrinology, the cardiovascular system, hematology, the respiratory system and water balance. PMID: 29654495 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 13, 2018 Category: Anesthesiology Authors: Kohlhepp LM, Hollerich G, Vo L, Hofmann-Kiefer K, Rehm M, Louwen F, Zacharowski K, Weber CF Tags: Anaesthesist Source Type: research

[S3 guidelines on intensive medical care of cardiac surgery patients : Hemodynamic monitoring and cardiovascular system-an update].
This article describes the most important innovations of these comprehensive guidelines. PMID: 29644444 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 11, 2018 Category: Anesthesiology Authors: Habicher M, Zajonz T, Heringlake M, Böning A, Treskatsch S, Schirmer U, Markewitz A, Sander M Tags: Anaesthesist Source Type: research

[Perioperative onset of sarcoidosis : Rare differential diagnosis of a  difficult airway].
This article describes the onset of sarcoidosis in a case of an unexpected difficult airway. PMID: 29644445 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 11, 2018 Category: Anesthesiology Authors: Jansen G, Nowak A Tags: Anaesthesist Source Type: research

[The heart catheter table is not the operating table : Intraindividual comparison of pulmonary artery pressures].
CONCLUSION: An elevated pulmonary pressure obtained preoperatively during right heart catheterization is not indicative of an elevated pulmonary pressure either intraoperatively or postoperatively. There are various explanations for the differences (e.g., different physiological and pathophysiological settings, such as sedation with potential hypercapnia versus anesthesia with vasodilation when measured; newly prescribed medication coming into effect between the right heart catheterization and surgery; intraoperative positioning). Even though the inherent risks of a PAC seem to be low, we recommend refraining from usi...
Source: Der Anaesthesist - April 5, 2018 Category: Anesthesiology Authors: Ziegler MU, Reinelt H Tags: Anaesthesist Source Type: research

[Mechanical circulatory support in terminal heart failure].
CONCLUSION: Due to the increasing number of patients on long-term mechanical circulatory support, the chances are that physicians in the initial emergency admission are unfamiliar with these devices but need to operate them in emergency cases. Therefore, knowledge of these procedures and their complications becomes increasingly important. PMID: 29623383 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - April 5, 2018 Category: Anesthesiology Authors: Derwall M, Moza A, Brücken A Tags: Anaesthesist Source Type: research

[Fatal flecainide intoxication in a 17-year-old girl].
Abstract A 17-year-old girl was found vomiting and somnolent at home and was taken to a hospital. The girl initially presented with ventricular tachycardia with broad QRS complexes which was very difficult to control. During the course a subsequent cardiogenic shock developed and despite exhaustion of all therapeutic options the fatal outcome could not be averted. The medicolegal autopsy revealed no evidence of any form of violence but the signs of medical treatment. Furthermore, no pathology of internal organs was detected. The toxicological analyses revealed a lethal intoxication with flecainide a...
Source: Der Anaesthesist - March 28, 2018 Category: Anesthesiology Authors: Dokter M, Talarico G, Armbrust S, Below E, Bockholdt B Tags: Anaesthesist Source Type: research

[Hypotheses must be tested].
PMID: 29594408 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 28, 2018 Category: Anesthesiology Authors: Bernhard M, Behrens NH, Fischer M Tags: Anaesthesist Source Type: research

[Can a supraglottic airway device really be avoided during resuscitation?]
PMID: 29582090 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 26, 2018 Category: Anesthesiology Authors: Rossi R Tags: Anaesthesist Source Type: research

[Palliative medicine in emergency medical services].
Abstract The scope of emergency calls for emergency medical services staffed by an emergency physician (EMS-EP) includes calls to patients with life-limiting diseases. Symptom exacerbation as well as psychosocial overburdening of caring relatives are the most frequent reasons for activation of an EMS-EP. Pain crises, acute dyspnea, massive bleeding and/or an impending or overt cardiac arrest are the most frequent symptom exacerbations. Under the conditions of a prehospital emergency physician mission, particular challenges are the evaluation of the overall situation, the prognosis and the presumed will of the...
Source: Der Anaesthesist - March 21, 2018 Category: Anesthesiology Authors: Roessler M, Eulitz N Tags: Anaesthesist Source Type: research

[Influence of social characteristics on the duration of treatment, severity of the disease and social support of patients in a surgical intensive care unit].
CONCLUSION: In addition to the SES, sociodemographic characteristics of the individual patient are associated with the course of treatment in intensive care medicine. The extent of social support by the next of kin depends on intercultural and individual patient characteristics. An increasing size of the town of residence and private health insurance status positively influence intensive care outcomes. In order to evaluate these data, further epidemiological studies in intensive care medicine are necessary. PMID: 29564474 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 21, 2018 Category: Anesthesiology Authors: Blecha S, Schlitt HJ, Graf BM, Leitzmann M, Bein T Tags: Anaesthesist Source Type: research

[Epigenetics : Important aspects for anesthesiologists, pain and intensive care physicians].
HL Abstract Epigenetics, i.e. an altered reading of the genome without altering the genes themselves is a growing scientific field. A distinction is made between changes in the DNA by modification of the histones and non-coding RNA that alter the messenger (m)RNAs. Epigenetic modifications can be triggered by personal circumstances or other external factors and therefore influence the occurrence of diseases. Epigenetics are therefore of particular interest to anesthesiologists, pain specialists and intensive care physicians, as anesthetic drugs may have a long-term influence on protein transcription lea...
Source: Der Anaesthesist - March 20, 2018 Category: Anesthesiology Authors: Reinhold AK, Jentho E, Schäfer ST, Bauer M, Rittner HL Tags: Anaesthesist Source Type: research

[Correction to: Telephone enquiries on the topic of malignant hyperthermia].
t H PMID: 29523895 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 9, 2018 Category: Anesthesiology Authors: Petersen B, Busch T, Meinecke CD, Bastian B, Kluba K, Kaisers UX, Rüffert H Tags: Anaesthesist Source Type: research