Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials
CONCLUSION: Despite challenges, observational methods and real-world data can be leveraged in certain important situations for a more timely evaluation of drug effectiveness and safety in more diverse and representative patient populations.PMID:37589143 | DOI:10.1177/17407745231193137 (Source: Clinical Trials)
Source: Clinical Trials - August 17, 2023 Category: Research Authors: Joshua D Wallach Yihong Deng Eric C Polley Sanket S Dhruva Jeph Herrin Kenneth Quinto Charu Gandotra William Crown Peter Noseworthy Xiaoxi Yao Molly Moore Jeffery Timothy D Lyon Joseph S Ross Rozalina G McCoy Source Type: research
Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials
CONCLUSION: Despite challenges, observational methods and real-world data can be leveraged in certain important situations for a more timely evaluation of drug effectiveness and safety in more diverse and representative patient populations.PMID:37589143 | DOI:10.1177/17407745231193137 (Source: Clinical Trials)
Source: Clinical Trials - August 17, 2023 Category: Research Authors: Joshua D Wallach Yihong Deng Eric C Polley Sanket S Dhruva Jeph Herrin Kenneth Quinto Charu Gandotra William Crown Peter Noseworthy Xiaoxi Yao Molly Moore Jeffery Timothy D Lyon Joseph S Ross Rozalina G McCoy Source Type: research
Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial
CONCLUSIONS: Adding a printed summary to a webpage (which significantly improved participant satisfaction) may increase costs to sites by ~£14/patient, which is modest in relation to the cost of trials. The Show RESPECT communication interventions were feasible to implement. This information could help future trials ensure they have sufficient resources to share results with participants.PMID:37515519 | DOI:10.1177/17407745231186088 (Source: Clinical Trials)
Source: Clinical Trials - July 29, 2023 Category: Research Authors: Annabelle South Julia Bailey Barbara E Bierer Eva Burnett William J Cragg Carlos Diaz-Montana Katie Gillies Talia Isaacs Nalinie Joharatnam-Hogan Claire Snowdon Matthew R Sydes Andrew J Copas Source Type: research
Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial
CONCLUSIONS: Adding a printed summary to a webpage (which significantly improved participant satisfaction) may increase costs to sites by ~£14/patient, which is modest in relation to the cost of trials. The Show RESPECT communication interventions were feasible to implement. This information could help future trials ensure they have sufficient resources to share results with participants.PMID:37515519 | DOI:10.1177/17407745231186088 (Source: Clinical Trials)
Source: Clinical Trials - July 29, 2023 Category: Research Authors: Annabelle South Julia Bailey Barbara E Bierer Eva Burnett William J Cragg Carlos Diaz-Montana Katie Gillies Talia Isaacs Nalinie Joharatnam-Hogan Claire Snowdon Matthew R Sydes Andrew J Copas Source Type: research
Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial
CONCLUSIONS: Adding a printed summary to a webpage (which significantly improved participant satisfaction) may increase costs to sites by ~£14/patient, which is modest in relation to the cost of trials. The Show RESPECT communication interventions were feasible to implement. This information could help future trials ensure they have sufficient resources to share results with participants.PMID:37515519 | DOI:10.1177/17407745231186088 (Source: Clinical Trials)
Source: Clinical Trials - July 29, 2023 Category: Research Authors: Annabelle South Julia Bailey Barbara E Bierer Eva Burnett William J Cragg Carlos Diaz-Montana Katie Gillies Talia Isaacs Nalinie Joharatnam-Hogan Claire Snowdon Matthew R Sydes Andrew J Copas Source Type: research
