Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
Controls, comparator arms, and designs for critical care comparative effectiveness research: It's complicated
CONCLUSION: Flawed critical care comparative effectiveness research trial designs can lead to unsound trial conclusions, compromise informed consent, and increase risks to research subjects, undermining the major goal of comparative effectiveness research: to inform current practice. Well-constructed control and comparator arms comprise indispensable elements of critical care comparative effectiveness research trials, key to improving the trials' safety and to generating trial results likely to improve patient outcomes in clinical practice.PMID:37615179 | DOI:10.1177/17407745231195094 (Source: Clinical Trials)
Source: Clinical Trials - August 24, 2023 Category: Research Authors: Verity J Ford Harvey G Klein Robert L Danner Willard N Applefeld Jeffrey Wang Irene Cortes-Puch Peter Q Eichacker Charles Natanson Source Type: research
