Comorbidities are associated with different features of severe asthma
According to ATS/ERS document on severe asthma (SA), the management of these patients requires the identification and proper treatment of comorbidities, which can influence the control of asthma. (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - December 3, 2018 Category: Allergy & Immunology Authors: Federica Novelli, Elena Bacci, Manuela Latorre, Veronica Seccia, Maria Laura Bartoli, Silvana Cianchetti, Federico Lorenzo Dente, Antonella Di Franco, Alessandro Celi and Pierluigi Paggiaro Tags: Research Source Type: research

Focus on the role of substance P in chronic urticaria
Emerging data have strengthened the importance of substance P (SP) as a proinflammatory mediator in human pathology. A role for SP in the pathogenesis of urticaria has long been hypothesized. (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - November 19, 2018 Category: Allergy & Immunology Authors: Gino A. Vena, Nicoletta Cassano, E. Di Leo, G. F. Calogiuri and Eustachio Nettis Tags: Review Source Type: research

Markers of atopic dermatitis, allergic rhinitis and bronchial asthma in pediatric patients: correlation with filaggrin, eosinophil major basic protein and immunoglobulin E
Allergic reactions have been implicated as contributions in a number of atopic disorders, including atopic dermatitis (AD), allergic rhinitis (AR) and bronchial asthma (BA). However, the potential for filaggri... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - November 12, 2018 Category: Allergy & Immunology Authors: Zafar Rasheed, Khaled Zedan, Ghada Bin Saif, Ragaa H. Salama, Tarek Salem, Ahmed A. Ahmed, Alaa Abd El-Moniem, Maha Elkholy, Ahmad A. Al Robaee and Abdullateef A. Alzolibani Tags: Research Source Type: research

Rapid desensitization for brentuximab vedotin (Adceteris ®) allergy: a case report
Brentuximab vedotin (BV) is an antibody –drug conjugate formed by an anti-CD30 chimeric IgG1 conjugated with monomethyl-auristatin-E. BV targets the CD30+ cells, which characterize Hodgkin lymphoma as well as anap... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - October 29, 2018 Category: Allergy & Immunology Authors: Attilio Di Girolamo, Marcello Albanesi, Alessandro Sinisi, Eustachio Nettis, Danilo Di Bona, Maria Filomena Caiaffa and Luigi Macchia Tags: Case Report Source Type: research

Drug induced Kounis syndrome: does oxidative stress play a role?
Kounis syndrome (KS) has been described as the coincidental occurrence of acute coronary syndromes during an allergic reaction with cardiac anaphylaxis. It is caused by inflammatory mediators released after ex... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - October 1, 2018 Category: Allergy & Immunology Authors: Luisa Ricciardi, Fabiana Furci, Marco Casciaro, Eleonora Di Salvo, Mariateresa Cristani, Valeria Tigano, Paola Lucia Minciullo and Sebastiano Gangemi Tags: Case Report Source Type: research

Urban air pollution and climate change: “The Decalogue: Allergy Safe Tree” for allergic and respiratory diseases care
According to the World Health Organization, air pollution is closely associated with climate change and, in particular, with global warming. In addition to melting of ice and snow, rising sea level, and floodi... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - September 11, 2018 Category: Allergy & Immunology Authors: Vincenzo Patella, Giovanni Florio, Diomira Magliacane, Ada Giuliano, Maria Angiola Crivellaro, Daniela Di Bartolomeo, Arturo Genovese, Mario Palmieri, Amedeo Postiglione, Erminia Ridolo, Cristina Scaletti, Maria Teresa Ventura and Anna Zollo Tags: Review Source Type: research

The involvement of osmolarity in the safety of contrast media
New non-ionic contrast agents, classified into low osmolar agents and iso-osmolar agents, present different biochemical characteristics that may influence the allergic reactions they cause. The aim of our stud... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - September 3, 2018 Category: Allergy & Immunology Authors: Stefania Isola, Fabiana Furci and Sebastiano Gangemi Tags: Case Report Source Type: research

Obituary
(Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - August 7, 2018 Category: Allergy & Immunology Tags: Obituary Source Type: research

Tryptase as a marker of severity of aortic valve stenosis
Severe aortic valve stenosis is one of the most common cause of mortality in adult patients affected with metabolic syndrome, a condition associated with an active inflammatory process involving also mast cell... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - August 7, 2018 Category: Allergy & Immunology Authors: Laura M. Losappio, Corrado Mirone, Michel Chevallard, Laura Farioli, Fabrizio De Luca and Elide A. Pastorello Tags: Case Report Source Type: research

Focus on the agents most frequently responsible for perioperative anaphylaxis
Adverse reactions (ARs) to drugs administered during general anesthesia may be very severe and life-threatening, with a mortality rate ranging from 3 to 9%. The adverse reactions to drugs may be IgE and non-Ig... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - July 9, 2018 Category: Allergy & Immunology Authors: E. Di Leo, P. Delle Donne, G. F. Calogiuri, L. Macchia and E. Nettis Tags: Review Source Type: research

House dust mite-related respiratory allergies and probiotics: a narrative review
The socio-economic burden of allergic respiratory conditions on continental Europe is even higher than that of mainstream diseases, such as diabetes and cardiovascular disease, as allergic rhinitis alone accou... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - June 19, 2018 Category: Allergy & Immunology Authors: Filippo Fassio and Fabio Guagnini Tags: Review Source Type: research

Sublingual grass allergen specific immunotherapy: a retrospective study of clinical outcome and discontinuation
Sublingual immunotherapy (SLIT) is effective, tolerable, and convenient for many allergic patients. Still, real-world evidence is scarce and the aim of this study is to assess the patient reported outcome of t... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - June 8, 2018 Category: Allergy & Immunology Authors: Christer Janson, Fredrik Sundbom, Peter Arvidsson and Mary K ämpe Tags: Research Source Type: research

Regulation of IgE activity in inhalational tolerance via formation of IgG anti-IgE/IgE immune complexes
Allergic asthma is an inflammatory disorder of the airways that results from inappropriate production of IgE against harmless, environmental antigens. Sequestration of free IgE using humanized IgG anti-IgE is ... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - May 18, 2018 Category: Allergy & Immunology Authors: Sonali J. Bracken, Alexander J. Adami, Ektor Rafti, Craig M. Schramm and Adam P. Matson Tags: Correspondence Source Type: research

Low incidence of pneumonia in COPD patients treated with inhaled corticosteroids undergoing pulmonary rehabilitation
Based on meta-analyses results, it is currently acknowledged that there is an increased risk of pneumonia in patients with chronic obstructive pulmonary disease (COPD) undergoing inhaled corticosteroids (ICS) ... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - May 16, 2018 Category: Allergy & Immunology Authors: Erminia Ridolo, Cristoforo Incorvaia, Irene Martignago, Laura Pessina, Fulvio Lauretani, Luciano Loperfido, Gian Galeazzo Riario-Sforza, Annalisa Broglia, Bruna L. Gritti and Lorenzo Panella Tags: Research Source Type: research

Involvement of miR-126 in autoimmune disorders
Micro-RNA represent a great family of small non-condign ribonucleic acid molecules; in particular microRNA-126 is an important member of this family and is expressed in many human cells such as cardiomyocytes,... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - May 2, 2018 Category: Allergy & Immunology Authors: Marco Casciaro, Eleonora Di Salvo, Teresa Brizzi, Carmelo Rodolico and Sebastiano Gangemi Tags: Review Source Type: research