Defining type 2 asthma and patients eligible for dupilumab in Italy: a biomarker-based analysis
Asthma is a chronic disease characterized by airway hyperresponsiveness, inflammation and mucus production. In Type 2 asthma, two phenotypic components are often co-expressed (eosinophilic and allergic). Eleva... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - May 21, 2021 Category: Allergy & Immunology Authors: Giorgio Walter Canonica, Francesco Blasi, Nunzio Crimi, Pierluigi Paggiaro, Alberto Papi, Francesca Fanelli, Annalisa Stassaldi and Gianluca Furneri Tags: Research Source Type: research
H2-antagonist in IgE-mediated type I hypersensitivity reactions: what literature says so far?
Histamine is a monoamine synthesized from the amino acid histidine that is well-known for its role in IgE-mediated anaphylaxis but has shown pleiotropic effects on the immune system, especially in order to pro... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - April 13, 2021 Category: Allergy & Immunology Authors: Matteo Borro, Simone Negrini, Andrew Long, Sharon Chinthrajah and Giuseppe Murdaca Tags: Letters to the Editor Source Type: research
Hereditary angioedema due to C1 inhibitor deficiency in Belarus: epidemiology, access to diagnosis and seven novel mutations in SERPING1 gene
Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare disease. Few states in developing countries have an adequate management of HAE, but none of them belongs to the former USSR area. Thi... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - April 7, 2021 Category: Allergy & Immunology Authors: Irina Guryanova, Chiara Suffritti, Debora Parolin, Andrea Zanichelli, Nastassia Ishchanka, Ekaterina Polyakova, Mikhail Belevtsev, Francesca Perego, Marco Cicardi, Yulia Zharankova, Natalya Konoplya, Sonia Caccia and Antonio Gidaro Tags: Research Source Type: research
Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite
Mugwort and house dust mite (HDM) are two of the most common inhalant allergens in Asia, however, whether mugwort affects polysensitized HDM+ allergic rhinitis (AR) patients has not been elucidated. (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - April 2, 2021 Category: Allergy & Immunology Authors: Su Duan, Limin Zhao, Yuling Zhang, Nan Zhang, Ming Zheng, Qiqi Wang, Xu Zhang, Xiangdong Wang, Sun Ying, Claus Bachert, Luo Zhang and Feng Lan Tags: Research Source Type: research
The effect of vitamin C on procalcitonin biomarker in community ‐acquired pneumonia
Community acquired pneumonia (CAP) is a prevalent low respiratory infection. Diagnosis is based on clinical symptoms, radiologic evidence and culture. Biomarkers such as IL6, CRP and procalcitonin are helpful ... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - March 3, 2021 Category: Allergy & Immunology Authors: Mahsa Nikzad, Hamid Reza Banafshe, Mansooreh Momen-Heravi, Hamed Haddad Kashani and Maryam Shiehmorteza Tags: Research Source Type: research
Dexamethasone and lidocaine suppress eosinophilopoiesis from umbilical cord blood cells
Eosinophils play an important role in allergic inflammation. Glucocorticosteroids have been used as an anti-inflammatory medication for inflammatory diseases involving eosinophil infiltration. Some effect of n... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - December 2, 2020 Category: Allergy & Immunology Authors: Masato Muraki, Hirohito Kita and Gerald J. Gleich Tags: Research Source Type: research
Vitamin D and Covid-19: an update on evidence and potential therapeutic implications
The world is now experiencing its third major epidemic of coronavirus (CoV) infections began in Wuhan, Hubei, China, in late 2019 and named COVID-19. After an initial explosive outbreak of pneumonia of unknown... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - November 19, 2020 Category: Allergy & Immunology Authors: Giuseppe Murdaca, Giovanni Pioggia and Simone Negrini Tags: Review Source Type: research
Safety of measles, mumps, and rubella vaccine in egg allergy: in vivo and in vitro management
Egg allergy is the second most prevalent form of food allergy in childhood. In spite of the evidence accumulated, inoculating egg allergy children with attenuated vaccines grown on chick embryo cell cultures, ... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - November 15, 2020 Category: Allergy & Immunology Authors: Stefania Magist à, Marcello Albanesi, Nada Chaoul, Danilo Di Bona, Elisabetta Di Leo, Eustachio Nettis, Maria Filomena Caiaffa and Luigi Macchia Tags: Case Report Source Type: research
Oral health in asthmatic patients: a review
This article reviews the evide... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - November 7, 2020 Category: Allergy & Immunology Authors: Federica Gani, Marco Caminati, Fabio Bellavia, Andrea Baroso, Paolo Faccioni, Paolo Pancera, Veronica Batani and Gianenrico Senna Tags: Review Source Type: research
Physicians ’ prescribing behaviour and clinical practice patterns for allergic rhinitis management in Italy
Despite availability of clinical guidelines, underdiagnosis, undertreatment, and poor adherence are still significant concerns in allergic rhinitis (AR) therapeutic management. We investigated clinical practic... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - November 3, 2020 Category: Allergy & Immunology Authors: Giovanni Passalacqua, Antonino Musarra, Gianenrico Senna, Jean Bousquet, Carmen Ferrara, Caterina Lonati and Giorgio Walter Canonica Tags: Research Source Type: research
A case report of toxic epidermal necrolysis (TEN) in a patient with COVID-19 treated with hydroxychloroquine: are these two partners in crime?
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) is the most Serious Cutaneous Adverse Reaction (SCAR) often with a fatal outcome. Coronavirus Disease (COVID-19) is caused by Severe Acute Respirat... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - October 6, 2020 Category: Allergy & Immunology Authors: Carlo Maria Rossi, Flavio Niccol ò Beretta, Grazia Traverso, Sandro Mancarella and Davide Zenoni Tags: Case Report Source Type: research
Management of the patient with allergic and immunological disorders in the pandemic COVID-19 era
The pandemic COVID-19 abruptly exploded, taking most health professionals around the world unprepared. Italy, the first European country to be hit violently, was forced to activate the lockdown in mid-February... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - October 1, 2020 Category: Allergy & Immunology Authors: Vincenzo Patella, Gabriele Delfino, Giovanni Florio, Giuseppe Spadaro, Fulvia Chieco Bianchi, Gianerico Senna and Mario Di Gioacchino Tags: Review Source Type: research
Hydroxychloroquine and dexamethasone in COVID-19: who won and who lost?
On June 30, 2020, the WHO reported over 10 millions of COVID-19 cases worldwide with over half a million deaths. In severe cases the disease progresses into an Acute Respiratory Distress Syndrome (ARDS), which... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - September 9, 2020 Category: Allergy & Immunology Authors: Claudio Ortolani and Elide A. Pastorello Tags: Review Source Type: research
Tranexamic acid adverse reactions: a brief summary for internists and emergency doctors
Tranexamic acid (TXA) is a synthetic lysine analogue that is well known as antifibrinolytic agent. It can reduce blood loss in clinical use, especially in conditions where fibrinolysis or hyperfibrinolysis are... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - September 3, 2020 Category: Allergy & Immunology Authors: Giuseppe Murdaca, Monica Greco, Chiara Vassallo and Sebastiano Gangemi Tags: Review Source Type: research
Allergic rhinitis and asthma symptoms in a real-life study of MP-AzeFlu to treat multimorbid allergic rhinitis and asthma
Asthma affects up to nearly 40% of patients with allergic rhinitis (AR). Poor control of AR symptoms is associated with poor asthma control. The goal of this study was to evaluate the effect of AR treatment wi... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - August 6, 2020 Category: Allergy & Immunology Authors: David Price, Ludger Klimek, Gabriella G álffy, Melanie Emmeluth, Arkady Koltun, Ferdinand Kopietz, Duc Tung Nguyen, Ranny van Weissenbruch, Wolfgang Pohl, Hans-Christian Kuhl, Glenis Scadding and Joaquim Mullol Tags: Research Source Type: research
