Fast satellite DNA evolution in Nothobranchius annual killifishes
Chromosome Res. 2023 Nov 21;31(4):33. doi: 10.1007/s10577-023-09742-8.ABSTRACTSatellite DNA (satDNA) is a rapidly evolving class of tandem repeats, with some monomers being involved in centromere organization and function. To identify repeats associated with (peri)centromeric regions, we investigated satDNA across Southern and Coastal clades of African annual killifishes of the genus Nothobranchius. Molecular cytogenetic and bioinformatic analyses revealed that two previously identified satellites, designated here as NkadSat01-77 and NfurSat01-348, are associated with (peri)centromeres only in one lineage of the Southern c...
Source: Chromosome Research - November 20, 2023 Category: Genetics & Stem Cells Authors: Anna Volen íková Karol ína Lukšíková Pablo Mora Tom áš Pavlica Marie Altmanov á Jana Štundlová Šárka Pelikánová Sergey A Simanovsky Marek Jank ásek Martin Reichard Petr Nguyen Alexandr Sember Source Type: research
Fast satellite DNA evolution in Nothobranchius annual killifishes
Chromosome Res. 2023 Nov 21;31(4):33. doi: 10.1007/s10577-023-09742-8.ABSTRACTSatellite DNA (satDNA) is a rapidly evolving class of tandem repeats, with some monomers being involved in centromere organization and function. To identify repeats associated with (peri)centromeric regions, we investigated satDNA across Southern and Coastal clades of African annual killifishes of the genus Nothobranchius. Molecular cytogenetic and bioinformatic analyses revealed that two previously identified satellites, designated here as NkadSat01-77 and NfurSat01-348, are associated with (peri)centromeres only in one lineage of the Southern c...
Source: Chromosome Research - November 20, 2023 Category: Genetics & Stem Cells Authors: Anna Volen íková Karol ína Lukšíková Pablo Mora Tom áš Pavlica Marie Altmanov á Jana Štundlová Šárka Pelikánová Sergey A Simanovsky Marek Jank ásek Martin Reichard Petr Nguyen Alexandr Sember Source Type: research
Fast satellite DNA evolution in Nothobranchius annual killifishes
Chromosome Res. 2023 Nov 21;31(4):33. doi: 10.1007/s10577-023-09742-8.ABSTRACTSatellite DNA (satDNA) is a rapidly evolving class of tandem repeats, with some monomers being involved in centromere organization and function. To identify repeats associated with (peri)centromeric regions, we investigated satDNA across Southern and Coastal clades of African annual killifishes of the genus Nothobranchius. Molecular cytogenetic and bioinformatic analyses revealed that two previously identified satellites, designated here as NkadSat01-77 and NfurSat01-348, are associated with (peri)centromeres only in one lineage of the Southern c...
Source: Chromosome Research - November 20, 2023 Category: Genetics & Stem Cells Authors: Anna Volen íková Karol ína Lukšíková Pablo Mora Tom áš Pavlica Marie Altmanov á Jana Štundlová Šárka Pelikánová Sergey A Simanovsky Marek Jank ásek Martin Reichard Petr Nguyen Alexandr Sember Source Type: research
Fast satellite DNA evolution in Nothobranchius annual killifishes
Chromosome Res. 2023 Nov 21;31(4):33. doi: 10.1007/s10577-023-09742-8.ABSTRACTSatellite DNA (satDNA) is a rapidly evolving class of tandem repeats, with some monomers being involved in centromere organization and function. To identify repeats associated with (peri)centromeric regions, we investigated satDNA across Southern and Coastal clades of African annual killifishes of the genus Nothobranchius. Molecular cytogenetic and bioinformatic analyses revealed that two previously identified satellites, designated here as NkadSat01-77 and NfurSat01-348, are associated with (peri)centromeres only in one lineage of the Southern c...
Source: Chromosome Research - November 20, 2023 Category: Genetics & Stem Cells Authors: Anna Volen íková Karol ína Lukšíková Pablo Mora Tom áš Pavlica Marie Altmanov á Jana Štundlová Šárka Pelikánová Sergey A Simanovsky Marek Jank ásek Martin Reichard Petr Nguyen Alexandr Sember Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
Chromosome instability and aneuploidy in the mammalian brain
Chromosome Res. 2023 Nov 1;31(4):32. doi: 10.1007/s10577-023-09740-w.ABSTRACTThis review investigates the role of aneuploidy and chromosome instability (CIN) in the aging brain. Aneuploidy refers to an abnormal chromosomal count, deviating from the normal diploid set. It can manifest as either a deficiency or excess of chromosomes. CIN encompasses a broader range of chromosomal alterations, including aneuploidy as well as structural modifications in DNA. We provide an overview of the state-of-the-art methodologies utilized for studying aneuploidy and CIN in non-tumor somatic tissues devoid of clonally expanded populations ...
Source: Chromosome Research - November 1, 2023 Category: Genetics & Stem Cells Authors: Olivia Albert Shixiang Sun Anita Huttner Zhengdong Zhang Yousin Suh Judith Campisi Jan Vijg Cristina Montagna Source Type: research
