Aza-Heterocyclic Building Blocks with In-Ring CF < sub > 2 < /sub > -Fragment
Chem Rec. 2023 Oct 24:e202300283. doi: 10.1002/tcr.202300283. Online ahead of print.ABSTRACTModern organic chemistry is a titan supporting and reinforcing pharmaceutical, agricultural, food and material science products. Over the past decades, the organic compounds market has been evolving to meet all the research demands. In this regard, medicinal chemistry is especially dependent on available chemical space as subtle tuning of the molecule structure is required to create a drug with relevant physicochemical properties and a remarkable activity profile. The recent rapid evolution of synthetic methodology to deploy fluorin...
Source: Chemical Record - October 24, 2023 Category: Chemistry Authors: S V Ryabukhin D V Bondarenko S A Trofymchuk D A Lega D M Volochnyuk Source Type: research
Excitonic Properties of Organic Dye Aggregates: Contribution of Ukrainian Science
Chem Rec. 2023 Oct 24:e202300290. doi: 10.1002/tcr.202300290. Online ahead of print.ABSTRACTUnexpected discovery that molecules of organic dyes when they form regular structures can change dramatically their light absorption and fluorescence properties were attracting the minds of researchers for more than eight decades. The progress in investigation of this unique phenomenon described in terms of H- and J-aggregation has led to many practical applications. Here the author expresses his personal view on the dramatic story of switching this research area from empirical knowledge to that standing on strong background of mole...
Source: Chemical Record - October 24, 2023 Category: Chemistry Authors: Alexander P Demchenko Source Type: research
Recent Theoretical and Experimental Advancements of Aluminum-Sulfur Batteries
Chem Rec. 2023 Oct 24:e202300268. doi: 10.1002/tcr.202300268. Online ahead of print.ABSTRACTAluminum-sulfur batteries (AlSBs) exhibit significant potential as energy storage systems due to their notable attributes, including a high energy density, cost-effectiveness, and abundant availability of aluminum and sulfur. In order to commercialize AlSBs, an understanding of their working principles is necessary. In this review, we examine the current advancements in cathodes, both in theory and practice, as well as the progress made in aqueous and nonaqueous electrolytes. We also explore the modifications made to separators and ...
Source: Chemical Record - October 24, 2023 Category: Chemistry Authors: Muhammad Faheem Arshad Hussain Muhammad Ali Md Abdul Aziz Source Type: research
Menthol-Based (Deep) Eutectic Solvents: A Review on Properties and Application in Extraction
Chem Rec. 2023 Oct 20:e202300267. doi: 10.1002/tcr.202300267. Online ahead of print.ABSTRACTIn the last 10 years the interest in deep eutectic solvents (DESs) as a new class of green solvents has considerably increased. The emergence of numerous of hydrophobic DESs has stimulated intensive research into their application in extraction technologies, including sample preparation. As the properties of such systems are highly dependent on the properties of their components (hydrogen bond donors and acceptors) and can be finely tuned, DESs can be successfully used for the extraction of both metal ions and organic substances, in...
Source: Chemical Record - October 20, 2023 Category: Chemistry Authors: Marharyta Cherniakova Victoria Varchenko Konstantin Belikov Source Type: research
Menthol-Based (Deep) Eutectic Solvents: A Review on Properties and Application in Extraction
Chem Rec. 2023 Oct 20:e202300267. doi: 10.1002/tcr.202300267. Online ahead of print.ABSTRACTIn the last 10 years the interest in deep eutectic solvents (DESs) as a new class of green solvents has considerably increased. The emergence of numerous of hydrophobic DESs has stimulated intensive research into their application in extraction technologies, including sample preparation. As the properties of such systems are highly dependent on the properties of their components (hydrogen bond donors and acceptors) and can be finely tuned, DESs can be successfully used for the extraction of both metal ions and organic substances, in...
Source: Chemical Record - October 20, 2023 Category: Chemistry Authors: Marharyta Cherniakova Victoria Varchenko Konstantin Belikov Source Type: research
Menthol-Based (Deep) Eutectic Solvents: A Review on Properties and Application in Extraction
Chem Rec. 2023 Oct 20:e202300267. doi: 10.1002/tcr.202300267. Online ahead of print.ABSTRACTIn the last 10 years the interest in deep eutectic solvents (DESs) as a new class of green solvents has considerably increased. The emergence of numerous of hydrophobic DESs has stimulated intensive research into their application in extraction technologies, including sample preparation. As the properties of such systems are highly dependent on the properties of their components (hydrogen bond donors and acceptors) and can be finely tuned, DESs can be successfully used for the extraction of both metal ions and organic substances, in...
Source: Chemical Record - October 20, 2023 Category: Chemistry Authors: Marharyta Cherniakova Victoria Varchenko Konstantin Belikov Source Type: research
Menthol-Based (Deep) Eutectic Solvents: A Review on Properties and Application in Extraction
Chem Rec. 2023 Oct 20:e202300267. doi: 10.1002/tcr.202300267. Online ahead of print.ABSTRACTIn the last 10 years the interest in deep eutectic solvents (DESs) as a new class of green solvents has considerably increased. The emergence of numerous of hydrophobic DESs has stimulated intensive research into their application in extraction technologies, including sample preparation. As the properties of such systems are highly dependent on the properties of their components (hydrogen bond donors and acceptors) and can be finely tuned, DESs can be successfully used for the extraction of both metal ions and organic substances, in...
Source: Chemical Record - October 20, 2023 Category: Chemistry Authors: Marharyta Cherniakova Victoria Varchenko Konstantin Belikov Source Type: research
Transition Metals-Based Water Splitting Electrocatalysts on Copper-Based Substrates: The Integral Role of Morphological Properties
Chem Rec. 2023 Oct 19:e202300228. doi: 10.1002/tcr.202300228. Online ahead of print.ABSTRACTElectrocatalytic water splitting is a promising alternative to produce high purity hydrogen gas as the green substitute for renewable energy. Thus, development of electrocatalysts for both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) are vital to improve the efficiency of the water splitting process particularly based on transition metals which has been explored extensively to replace the highly active electrocatalytic activity of the iridium and ruthenium metals-based electrocatalysts. In situ growth of the...
Source: Chemical Record - October 19, 2023 Category: Chemistry Authors: Shankary Selvanathan Pei Meng Woi Vidhya Selvanathan Mohammad Rezaul Karim Kamaruzzaman Sopian Md Akhtaruzzaman Source Type: research
Design and Photonics of Merocyanine Dyes
Chem Rec. 2023 Oct 18:e202300262. doi: 10.1002/tcr.202300262. Online ahead of print.ABSTRACTMerocyanines, thanks to their easily adjustable electronic structure, appear to be the most versatile and promising functional dyes. Their D-π-A framework offers ample opportunities for custom design through variations in both donor/acceptor end-groups and the π-conjugated polymethine chain, and leads to a broad range of practical properties, including noticeable solvatochromism, high polarizability/hyperpolarizabilities, and the ability to sensitize various physicochemical processes. Accordingly, merocyanines are applied and exte...
Source: Chemical Record - October 18, 2023 Category: Chemistry Source Type: research
Design and Photonics of Merocyanine Dyes
Chem Rec. 2023 Oct 18:e202300262. doi: 10.1002/tcr.202300262. Online ahead of print.ABSTRACTMerocyanines, thanks to their easily adjustable electronic structure, appear to be the most versatile and promising functional dyes. Their D-π-A framework offers ample opportunities for custom design through variations in both donor/acceptor end-groups and the π-conjugated polymethine chain, and leads to a broad range of practical properties, including noticeable solvatochromism, high polarizability/hyperpolarizabilities, and the ability to sensitize various physicochemical processes. Accordingly, merocyanines are applied and exte...
Source: Chemical Record - October 18, 2023 Category: Chemistry Source Type: research
Layered Double Hydroxides as the Unique Product of Target Ionic Construction for Energy, Chemical, Foods, Cosmetics, Medicine and Ecology Applications
Chem Rec. 2023 Oct 17:e202300260. doi: 10.1002/tcr.202300260. Online ahead of print.ABSTRACTLayered Double Hydroxide (LDH) is an α-modification of the M-host (M2+ ) hydroxide, in which some part of the M-host cations is replaced by M-guest cations (M3+ or M4+ ). The emerging excess positive charge is compensated by the intercalation of anions into the interlayer space, which also contains water molecules. LDHs exhibit anion exchange properties. Targeted ionic design of LDHs via combining three components (M-host, M-guest cations, intercalated anions) allows the creation of a very wide range of highly efficient electrochem...
Source: Chemical Record - October 17, 2023 Category: Chemistry Authors: Vadym Kovalenko Valerii Kotok Bohdan Murashevych Source Type: research
Insights into Modeling Approaches in Chemistry: Assessing Ligand-Protein Binding Thermodynamics Based on Rigid-Flexible Model Molecules
Chem Rec. 2023 Oct 17:e202300276. doi: 10.1002/tcr.202300276. Online ahead of print.ABSTRACTIn the field of chemistry, model compounds find extensive use for investigating complex objects. One prime example of such object is the protein-ligand supramolecular interaction. Prediction the enthalpic and entropic contribution to the free energy associated with this process, as well as the structural and dynamic characteristics of protein-ligand complexes poses considerable challenges. This review exemplifies modeling approaches used to study protein-ligand binding (PLB) thermodynamics by employing pairs of conformationally cons...
Source: Chemical Record - October 17, 2023 Category: Chemistry Authors: Igor V Komarov Volodymyr A Bugrov Anton Cherednychenko Oleksandr O Grygorenko Source Type: research
Layered Double Hydroxides as the Unique Product of Target Ionic Construction for Energy, Chemical, Foods, Cosmetics, Medicine and Ecology Applications
Chem Rec. 2023 Oct 17:e202300260. doi: 10.1002/tcr.202300260. Online ahead of print.ABSTRACTLayered Double Hydroxide (LDH) is an α-modification of the M-host (M2+ ) hydroxide, in which some part of the M-host cations is replaced by M-guest cations (M3+ or M4+ ). The emerging excess positive charge is compensated by the intercalation of anions into the interlayer space, which also contains water molecules. LDHs exhibit anion exchange properties. Targeted ionic design of LDHs via combining three components (M-host, M-guest cations, intercalated anions) allows the creation of a very wide range of highly efficient electrochem...
Source: Chemical Record - October 17, 2023 Category: Chemistry Authors: Vadym Kovalenko Valerii Kotok Bohdan Murashevych Source Type: research
Insights into Modeling Approaches in Chemistry: Assessing Ligand-Protein Binding Thermodynamics Based on Rigid-Flexible Model Molecules
Chem Rec. 2023 Oct 17:e202300276. doi: 10.1002/tcr.202300276. Online ahead of print.ABSTRACTIn the field of chemistry, model compounds find extensive use for investigating complex objects. One prime example of such object is the protein-ligand supramolecular interaction. Prediction the enthalpic and entropic contribution to the free energy associated with this process, as well as the structural and dynamic characteristics of protein-ligand complexes poses considerable challenges. This review exemplifies modeling approaches used to study protein-ligand binding (PLB) thermodynamics by employing pairs of conformationally cons...
Source: Chemical Record - October 17, 2023 Category: Chemistry Authors: Igor V Komarov Volodymyr A Bugrov Anton Cherednychenko Oleksandr O Grygorenko Source Type: research
Cyclizations of Alkenyl(Alkynyl)-Functionalized Quinazolinones and their Heteroanalogues: a Powerful Strategy for the Construction of Polyheterocyclic Structures
Chem Rec. 2023 Oct 13:e202300255. doi: 10.1002/tcr.202300255. Online ahead of print.ABSTRACTQuinazolin-4-one, its heteroanalogues, and derivatives represent an outstandingly important class of compounds in modern organic, medicinal, and pharmaceutical chemistry, as these molecular structures are noted for their wide synthetic and pharmacological potential. In the last years, ever-increasing research attention has been paid to quinazolinone derivatives bearing alkenyl and alkynyl substituents on the pyrimidinone nucleus. The original structural combination of synthetically powerful endocyclic amidine (or amidine-related) an...
Source: Chemical Record - October 13, 2023 Category: Chemistry Authors: Alla Vaskevych Maryna Dekhtyar Mykhailo Vovk Source Type: research
