Dyslipidemia in Patients with Kidney Disease
This article focuses on epidemiology of CKD, how dyslipidemias confer a higher risk for CVD, the approach to management and treatment of dyslipidemias, and recent guidelines. (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Aneesha Thobani, Terry A. Jacobson Source Type: research

The Impact of Uric Acid and Hyperuricemia on Cardiovascular and Renal Systems
The description of gout dates back almost 5000  years, and scientific interest in uric acid increased when it was found to be involved in the pathogenesis of gout. Since then, many basic and clinical studies have assessed the implications of uric acid for the oxidative system, inflammation, and cardiovascular and renal outcomes. Uric acid–low ering therapy failed to improve clinical hard outcomes in asymptomatic hyperuricemia, and it is retained in symptomatic hyperuricemia. Dietary and lifestyle modifications are critical to manage hyperuricemia. More studies are warranted to investigate the role of uric acid–lowerin...
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Davide Agnoletti, Arrigo F.G. Cicero, Claudio Borghi Source Type: research

Advances in Diagnosis and Treatment of Cardiac and Renal Amyloidosis
Diagnoses of amyloidosis are increasing annually, and advances in bone scintigraphy and cardiac MRI accompanied by development of nonbiopsy diagnostic criteria have specifically led to a huge increase in transthyretin amyloidosis cardiomyopathy (ATTR-CM) diagnoses worldwide. Tafamidis use is increasing, and there are several ongoing phase III clinical trials of novel agents that promise to transform the treatment landscape for patients with ATTR-CM. In systemic light chain (AL) amyloidosis, more effective chemotherapeutic agents continue to improve patient outcomes. Accelerating the removal of amyloid deposits to accompany...
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Steven Law, Marianna Fontana, Julian D. Gillmore Source Type: research

Atherosclerotic Vascular Disease Associated with Chronic Kidney Disease
Cardiovascular risk increases as glomerular filtration rate (GFR) declines in progressive renal disease and is maximal in patients with end-stage renal disease requiring maintenance dialysis. Atherosclerotic vascular disease, for which hyperlipidemia is the main risk factor and lipid-lowering therapy is the key intervention, is common. However, the pattern of dyslipidemia changes with low GFR and the association with vascular events becomes less clear. While the pathophysiology and management of patients with early chronic kidney disease (CKD) is similar to the general population, advanced and end-stage CKD is characterize...
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Matthew J. Tunbridge, Alan G. Jardine Source Type: research

Nonatherosclerotic Vascular Abnormalities Associated with Chronic Kidney Disease
Nonatherosclerotic vascular diseases are manifested by endothelial dysfunction, hypertension, vascular calcification, coronary microvascular dysfunction, and calciphylaxis. Unfortunately, there are no definitive treatments for many of these disorders other than hypertension. In addition, although hypertension is more difficult to treat in the chronic kidney disease population, it is necessary to try and target a blood pressure of less than 130/80  mm Hg through the use of aggressive angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, diuretics, and other antihypertensive medications. New therapies are ...
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Rajesh Mohandas, Gajapathiraju Chamarthi, Mark S. Segal Source Type: research

A Comparison of Hemodialysis and Peritoneal Dialysis in Patients with Cardiovascular Disease
This article reviews and compares hemodialysis and peritoneal dialysis in association with different cardiovascular diseases affecting dialysis patients, including hypertension, coronary artery disease, myocardial stunning, cardiac arrhythmias, heart failure, and the cardiorenal syndrome. (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Rehab B. Albakr, Joanne M. Bargman Source Type: research

Cardiorenal Syndrome
Coexisting dysfunction of heart and kidney, the cardiorenal syndrome, is a common condition and is associated with worsening of outcomes and complexities of diagnostic, preventive, and therapeutic approaches. The knowledge of the physiology of heart and kidney and their interaction with each other and with other organ systems has progressed significantly in recent years, resulting in a better understanding of the pathogenesis of cardiorenal syndrome. A robust knowledge of the pathophysiology and of the latest practical advancements about cardiorenal syndrome is necessary for cardiologists, nephrologists, and other practiti...
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Parta Hatamizadeh Source Type: research

Time to Recognize Nephrocardiology as a Discipline
There is a large intersection between nephrology and cardiovascular medicine, which has grown over time with the advancement of the two subspecialties. Although cardiorenal syndrome is probably the most recognized entity in nephrocardiology, the field includes a much broader spectrum of topics, many of which have been studied by investigators in nephrology, cardiology, and other specialties, even though they might have not been portrayed as a nephrocardiology-related condition. (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Parta Hatamizadeh Tags: Preface Source Type: research

Nephrocardiology
CARDIOLOGY CLINICS (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Authors: Parta Hatamizadeh Source Type: research

Copyright
ELSEVIER (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Source Type: research

Contributors
JAMIL A. ABOULHOSN, MD, FACC, FSCAI (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Source Type: research

Contents
Parta Hatamizadeh (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Source Type: research

Forthcoming Issues
Vascular Medicine (Source: Cardiology Clinics)
Source: Cardiology Clinics - July 9, 2021 Category: Cardiology Source Type: research

Optimal Timing of Surgery for Patients with Active Infective Endocarditis
This article reviews the necessary evaluation for patients with suspected IE and proposes a state-of-the-art patient flow chart for evaluation of suspected IE. (Source: Cardiology Clinics)
Source: Cardiology Clinics - April 22, 2021 Category: Cardiology Authors: Takeshi Kitai, Akiko Masumoto, Taiji Okada, Tadaaki Koyama, Yutaka Furukawa Source Type: research

Echocardiographic Evaluation of Successful Mitral Valve Repair or Need for a Second Pump Run in the Operating Room
Detailed preoperative and intraoperative echocardiographic assessment of the mitral valve apparatus is critical for a successful repair. The recent advent of 3-dimensional transesophageal echocardiography has added an extra pivotal role to transesophageal echocardiography in the assessment of mitral apparatus and mitral regurgitation. Because surgeons must rapidly decide whether cardiopulmonary bypass should be continued to be weaned off or a second pump run should be selected, the echocardiographer conducting intraoperative transesophageal echocardiography is required to be trained according to a certain algorithm. This r...
Source: Cardiology Clinics - April 22, 2021 Category: Cardiology Authors: Mitsuhiko Ota, Takeshi Kitai Source Type: research