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Association among self-compassion, childhood invalidation, and borderline personality disorder symptomatology in a Singaporean sample
ConclusionThis study provides evidence in support of aspects of the biosocial model in an Asian context, and demonstrates a strong association between self-compassion and borderline personality disorder symptoms, independent of one ’s history of parental invalidation during childhood. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - November 28, 2017 Category: Psychiatry Source Type: research

The mediating role of mentalizing capacity between parents and peer attachment and adolescent borderline personality disorder
ConclusionsThe current study is the first to evaluate this mediational model with parent and peer attachment as separate concepts and the first to do so in a sample of adolescents who meet full or sub-threshold criteria for borderline personality disorder. Findings incrementally support that mentalizing capacity and attachment insecurity, also in relation to peers, are important concepts in theoretical approaches to the development of borderline personality disorder in adolescence. Clinical implications are discussed. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - November 24, 2017 Category: Psychiatry Source Type: research

The impact of borderline personality disorder and sub-threshold borderline personality disorder on the course of self-reported and clinician-rated depression in self-harming adolescents
ConclusionOur findings suggest that a diagnosis of BPD may have a strong impact on the assessment and course of depressive symptoms in self-harming adolescents. Although rated as equally depressed, adolescents with BPD self-reported significantly higher levels of depressive symptoms and suicidal ideation at baseline, and showed a poorer outcome in terms of higher levels of depressive symptoms and lower levels of global functioning at trial completion compared to adolescents with sub-threshold BPD. Our findings suggest that receiving Dialectical Behaviour Therapy could lead to a greater reduction in depressive symptoms, alt...
Source: Borderline Personality Disorder and Emotion Dysregulation - October 31, 2017 Category: Psychiatry Source Type: research

A pilot open series of lamotrigine in DBT-treated eating disorders characterized by significant affective dysregulation and poor impulse control
ConclusionsAlthough our findings are limited by the confounds inherent in an open series, lamotrigine showed initial promise in reducing emotional instability and behavioral impulsivity in severely dysregulated eating-disordered patients. These preliminary results support further investigation of lamotrigine for eating disorders in rigorous controlled trials. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - October 8, 2017 Category: Psychiatry Source Type: research

Frontal EEG asymmetry in borderline personality disorder is associated with alexithymia
ConclusionsOur findings reveal that lower right frontal EEG asymmetry is associated with alexithymia in patients with BPD. This finding is in accordance with neurophysiological models of alexithymia that implicate a right hemisphere impairment in emotion processing, and could suggest frontal EEG asymmetry as a potential biomarker of relevant psychopathology in these patients. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - September 29, 2017 Category: Psychiatry Source Type: research

Standard 12 month dialectical behaviour therapy for adults with borderline personality disorder in a public community mental health setting
ConclusionsThe current study provides evidence for the effectiveness of standard DBT in publicly funded community mental health settings. As participants were assessed at the end of every module, it was possible to observe trends in symptom reduction during each stage of the intervention. Despite real-world limitations of applying DBT in community settings, the results of this study are comparable with more tightly controlled studies.Trial registrationClinicalTrials.gov ID:NCT03166579; Registered May 24th 2017 ‘retrospectively registered’ (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - September 23, 2017 Category: Psychiatry Source Type: research

Family Connections versus optimised treatment-as-usual for family members of individuals with borderline personality disorder: non-randomised controlled study
ConclusionsThe findings of the current study indicate that FC results in statistically significant improvements on key measures while OTAU does not yield comparable changes. Lack of significant change on all measures for OTAU suggests that a three session psycho-education programme is of limited benefit. Further research is warranted on programme components and long-term supports for family members. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - August 30, 2017 Category: Psychiatry Source Type: research

Variations of emotion dysregulation in borderline personality disorder: a latent profile analysis approach with adult psychiatric inpatients
ConclusionsAll three groups improved greatly over the course of hospital treatment, although they remained distinguishable at discharge, retaining their positions symptomatically relative to one another. Limitations, implications, and future directions are discussed. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - August 24, 2017 Category: Psychiatry Source Type: research

Trauma-related emotions and radical acceptance in dialectical behavior therapy for posttraumatic stress disorder after childhood sexual abuse
ConclusionsTrauma-related emotions and radical acceptance showed significant changes from the start to the end of DBT-PTSD. Future studies with larger sample sizes and control group designs are needed to test whether these changes are due to the treatment.Trial registrationClinicalTrials.gov, numberNCT00481000 (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - July 13, 2017 Category: Psychiatry Source Type: research

Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study
ConclusionsMore studies are needed to confirm the efficacy of ER  + M to decrease depressive symptoms and overall psychopathology.Trial registrationNCT02747134. Registered on 20 April 2016. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - July 5, 2017 Category: Psychiatry Source Type: research

Subtypes of borderline personality disorder patients: a cluster-analytic approach
ConclusionsThree meaningful subtypes of BPD patients were identified with distinct profiles. Differences were small, even when controlling for severity of PD pathology, suggesting a strong common factor underlying BPD. These results may represent a stepping stone toward research with larger samples aimed at replicating the findings and investigating differential trajectories of change, treatment outcomes, and treatment approaches for these subtypes.Trial registrationThe study was retrospectively registered 16 April 2010 in theNederlands Trial Register, no.NTR2292. (Source: Borderline Personality Disorder and Emotion Dysregulation)
Source: Borderline Personality Disorder and Emotion Dysregulation - July 3, 2017 Category: Psychiatry Source Type: research

Impact of therapist change after initial contact and traumatic burden on dropout in a naturalistic sample of inpatients with borderline pathology receiving dialectical behavior therapy
ConclusionsThis study supports the importance of therapy process variables as predictors of therapy dropout in borderline pathology. A change of therapist between DBT-briefing and treatment was associated with an increased vulnerability for dropping out of treatment and should therefore be avoided if possible. Against our hypotheses, a comorbid PTSD was even protective with regard to DBT dropout. Therefore, this severely suffering patient group should not be rejected from treatment assuming them to be too unstable for psychotherapy. However, results need to be replicated. ClinicalTrials.gov Identifier: NCT03018639, retrosp...
Source: Borderline Personality Disorder and Emotion Dysregulation - June 22, 2017 Category: Psychiatry Source Type: research

The role of DSM-5 borderline personality symptomatology and traits in the link between childhood trauma and suicidal risk in psychiatric patients
ConclusionsThe findings provide preliminary support for the proposed mediation model indicating that BPD features may help explain relations between childhood trauma and elevated suicidal risk in adult life, in particular for DSM-5 Section III personality traits of depressivity (e.g., pessimism, guilt, and shame) and perceptual dysregulation (e.g., dissociation). To reduce the suicidal risk among those with a history of childhood trauma, BPD features (including “Depressivity” and “Perceptual Dysregulation”) might be an important target of assessment, risk management, and treatment. However, other factors are likely...
Source: Borderline Personality Disorder and Emotion Dysregulation - June 18, 2017 Category: Psychiatry Source Type: research