Media optimization for CHO fed-batch processes using a DoE approach in automated high-throughput single use ambr15 bioreactors
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
Front-line of genome editing technology for animal cell engineering
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
Model-based strategy for cell culture seed train layout verified at lab scale
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
A method to determine and simulate the permeation through a gel matrix in a multi-organ-chip
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
Influenza vaccine titer determination using biolayer interferometry (BLI)
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
Comparison of CHO cell cultivation and mAbproduction in the Allegro™ XRS 20 and conventional rocker type single-use bioreactors
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
Characterization and performance of the Allegro™ STR 200 single-use stirred tank bioreactor
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
Novel cell engineering of the Unfolded Protein Response to achieve efficient therapeutic protein production cell line
(Source: BMC Proceedings)
Source: BMC Proceedings - December 13, 2015 Category: Biomedical Science Source Type: research
ReactionFlow: an interactive visualization tool for causality analysis in biological pathways
Conclusions
We evaluated ReactionFlow by providing our application to two domain experts who have significant experience with biomolecular pathways, after which we conducted a series of in-depth interviews focused on each of the four causality analysis tasks. Their feedback leads us to believe that our techniques could be useful to researchers who must be able to understand and analyze the complex nature of biological pathways. ReactionFlow is available at https://github.com/CreativeCodingLab/ReactionFlow. (Source: BMC Proceedings)
Source: BMC Proceedings - August 13, 2015 Category: Biomedical Science Source Type: research
Extended LineSets: a visualization technique for the interactive inspection of biological pathways
Conclusions
Based on interviews with domain experts and an analysis of two use cases, we show that our technique provides functionality not currently enabled by current techniques, and moreover that it helps biologists to better understand both inter-pathway connectivity and the hierarchical structure of biological elements within the pathways. (Source: BMC Proceedings)
Source: BMC Proceedings - August 13, 2015 Category: Biomedical Science Source Type: research
miRTarVis: an interactive visual analysis tool for microRNA-mRNA expression profile data
Conclusions
We reported findings from miRNA-mRNA expression profile data of asthma patients using miRTarVis in a case study. miRTarVis helps to predict and understand targets of miRNA from miRNA-mRNA expression profile data. (Source: BMC Proceedings)
Source: BMC Proceedings - August 13, 2015 Category: Biomedical Science Source Type: research
MoFlow: visualizing conformational changes in molecules as molecular flow improves understanding
Conclusions
Pathline-based representations of molecular motion are more easily understood than timeline representations. Pathline representations provide other advantages because they represent motion directly, rather than representing structure with inferred motion. (Source: BMC Proceedings)
Source: BMC Proceedings - August 13, 2015 Category: Biomedical Science Source Type: research
PathwayMatrix: visualizing binary relationships between proteins in biological pathways
Conclusions
We evaluated PathwayMatrix by conducting a series of in-depth interviews with domain experts who provided positive feedback, leading us to believe that our visualization technique could be helpful for the larger community of researchers utilizing pathway visualizations. PathwayMatrix is freely available at https://github.com/CreativeCodingLab/PathwayMatrix. (Source: BMC Proceedings)
Source: BMC Proceedings - August 13, 2015 Category: Biomedical Science Source Type: research
Highlights from the 5th Symposium on Biological Data Visualization: Part 2
(Source: BMC Proceedings)
Source: BMC Proceedings - August 13, 2015 Category: Biomedical Science Source Type: research
Bio-event definition in text mining towards event interconnection
(Source: BMC Proceedings)
Source: BMC Proceedings - August 6, 2015 Category: Biomedical Science Source Type: research