Interpreting quantitative RNA expression prognostic and predictive results generated from synchronous rather than solitary breast cancers
Biomarkers. 2024 Mar 5:1-3. doi: 10.1080/1354750X.2024.2324871. Online ahead of print.NO ABSTRACTPMID:38444305 | DOI:10.1080/1354750X.2024.2324871 (Source: Biomarkers)
Source: Biomarkers - March 6, 2024 Category: Research Authors: Steven Sorscher Priya Gor Source Type: research
< em > Ile105Val < /em > polymorphism in the < em > GSTP1 < /em > gene is associated with susceptibility to acute myeloid leukemia: an updated systematic review and meta-analysis
Conclusion: The GSTP1 Ile105Val polymorphism is significantly associated with AML susceptibility, especially among non-Asians. Further investigation should be performed to strengthen the current results.PMID:38428950 | DOI:10.1080/1354750X.2024.2326538 (Source: Biomarkers)
Source: Biomarkers - March 1, 2024 Category: Research Authors: Raphael Enrique Tiongco Neil David Cayanan Miljun Catacata Michael John Dominguez Source Type: research
High-tissue FRMD6 expression predicts better outcomes among colorectal cancer patients
This study aimed to explore the role of FRMD6 in CRC and to determine how well it works as a prognostic factor among CRC patients.METHODS: The tumor expression of FRMD6 was evaluated using immunohistochemistry in 538 colorectal patients operated on at Helsinki University Hospital. We assessed FRMD6 expression with clinicopathological parameters and the impact of FRMD6 expression on survival.RESULTS: Patients with a high FRMD6 expression exhibited a better prognosis (univariable hazard ratio [HR] 0.58, 95% confidence interval [CI] 0.41-0.81), with a 5-year disease-specific survival (DSS) of 66.3%. By contrast, patients with...
Source: Biomarkers - February 22, 2024 Category: Research Authors: Arthur von Koskull Jaana Hagstr öm Caj Haglund Tuomas Kaprio Camilla B öckelman Source Type: research
