Exocyclic DNA adducts and oxidative stress parameters: useful tools for biomonitoring exposure to aldehydes in smokers
CONCLUSION: These results are promising, and the study is now being conducted on a larger cohort with the aim of evaluating the impact of smoking cessation programs on the evolution of adducts profile and antioxidants activities.PMID:38506499 | DOI:10.1080/1354750X.2024.2333361 (Source: Biomarkers)
Source: Biomarkers - March 20, 2024 Category: Research Authors: H éléna Alamil Marie-Lise Colsoul Natacha Heutte Marie Van Der Schueren Laurence Galanti Mathilde Lechevrel Source Type: research
Exocyclic DNA adducts and oxidative stress parameters: useful tools for biomonitoring exposure to aldehydes in smokers
This study aims to investigate the relationship between a profile of nine aldehydes-induced DNA adducts and antioxidant activities, in order to evaluate new biomarkers of systemic exposure to aldehydes. Using our previously published UPLC-MS/MS method, adducts levels were quantified in the blood DNA of 34 active smokers. The levels of antioxidant vitamins (A, C and E), coenzyme Q10, β-carotene, superoxide dismutase (SOD) and autoantibodies against oxidized low-density lipoprotein were measured. Adducts induced by tobacco smoking-related aldehydes were quantified at levels reflecting an oxidative production from lipid pero...
Source: Biomarkers - March 20, 2024 Category: Research Authors: H éléna Alamil Marie-Lise Colsoul Natacha Heutte Marie Van Der Schueren Laurence Galanti Mathilde Lechevrel Source Type: research
Date ( < em > Phoenix dactylifera < /em > L. Mill) fruit enhances sexual performance via modulation of oxido-inflammatory mediators and purinergic signaling in hypertensive male rats
Conclusion: Findings presented in this study suggest that dietary inclusion of P. dactylifera could be useful in managing erectile dysfunction (ED) commonly observed in subjects with hypertension. Findings highlighted in this study thus provide the scientific basis supporting the folkloric use of P. dactylifera as a key ingredient in aphrodisiac supplements.PMID:38483941 | DOI:10.1080/1354750X.2024.2331502 (Source: Biomarkers)
Source: Biomarkers - March 14, 2024 Category: Research Authors: Adeniyi A Adebayo Ayokunle O Ademosun Ganiyu Oboh Source Type: research
