Knowledge, attitudes and demographic effect on menopausal experiences among Indian rural women
This study underscored the need for tailored interventions in rural settings, considering the influence of cultural, regional, and demographic factors on menopausal experiences. The findings contributed to bridging the research gap and emphasized the importance of individualized approaches for promoting the well-being of menopausal women in rural communities.PMID:38497080 | PMC:PMC10941773 | DOI:10.6026/973206300200175 (Source: Bioinformation)
Source: Bioinformation - March 18, 2024 Category: Bioinformatics Authors: N Sivasubramanian Chaudhari Pinalben Madhabhai Amita Shilpa Gottlieb B Mahalakshmi Payal Vaghela Sandeep Garg Source Type: research
Amino acid pattern reveals multi-functionality of ORF3 protein from HEV
Bioinformation. 2024 Feb 29;20(2):121-135. doi: 10.6026/973206300200121. eCollection 2024.ABSTRACTThe smallest open reading frame (ORF) encoded protein ORF3 of hepatitis E virus (HEV), recently, has been demonstrated to perform multiple functions besides accessory roles. ORF3 could act as a target for vaccine against HEV infections. The IDR (intrinsically disordered region); IDP (ID protein)/IDPR (ID protein region), plays critical role in various regulatory functions of viruses. The dark proteome of HEV-ORF3 protein including its structure and function was systematically examined by computer predictors to explicate its ro...
Source: Bioinformation - March 18, 2024 Category: Bioinformatics Authors: Zoya Shafat Asimul Islam Shama Parveen Source Type: research
Molecular docking analysis of flavonoids with AChE and BACE-1
Bioinformation. 2024 Feb 29;20(2):103-109. doi: 10.6026/973206300200103. eCollection 2024.ABSTRACTFlavonoids are promising therapeutics for the treatment of Alzheimer's disease (AD). Therefore, it is of interest to study the anti-AD potential of 35 flavonoids towards the inhibition of AchE and BACE-1. Hence, the physicochemical, pharmacokinetic parameters, toxicity risk and drug-likeliness of the selected 35 flavonoids were computed. Further, the molecular docking analysis of flavonoids with AChE and BACE-1 were completed. A binding energy of -10.42 kcal/mol Epicatechin gallate, -10.16 kcal/mol sterubin and -10.11 kcal/mol...
Source: Bioinformation - March 18, 2024 Category: Bioinformatics Authors: Sittarthan Viswanathan Thennavan Arumugam Kavimani Subramanian Rengaraj Sivaraj Vimalavathini Ramesh A Hannah Rachel Vasanthi Source Type: research
Deep breathing exercises in easing educational stress among Indian high school students
This study contributes vital insights into stress management strategies for higher secondary students, highlighting the efficacy of incorporating deep breathing exercises into their routine. The observed reductions in stress levels emphasize the potential benefits of practical stress reduction techniques within the educational milieu.PMID:38497065 | PMC:PMC10941770 | DOI:10.6026/973206300200156 (Source: Bioinformation)
Source: Bioinformation - March 18, 2024 Category: Bioinformatics Authors: B Mahalakshmi Katara Mittalben Ghemabhai Amita Shilpa Gottlieb N Sivasubramanian Padmavathi Parthasarathy Source Type: research
Astrovirology and terrestrial life survival
Bioinformation. 2024 Feb 29;20(2):146-150. doi: 10.6026/973206300200146. eCollection 2024.ABSTRACTMicrobial organisms have been implicated in several mass extinction events throughout Earth's planetary history. Concurrently, it can be reasoned from recent viral pandemics that viruses likely exacerbated the decline of life during these periods of mass extinction. The fields of exovirology and exobiology have evolved significantly since the 20th century, with early investigations into the varied atmospheric compositions of exoplanets revealing complex interactions between metallic and non-metallic elements. This diversity in...
Source: Bioinformation - March 18, 2024 Category: Bioinformatics Authors: Paul Shapshak Milad Zandi Charurut Somboonwit John T Sinnott Source Type: research
